Spinal cord nerve cells branching through the body resemble trees with limbs fanning out in every direction. But this image can also be used to tell the story of how these neurons, their jobs becoming more specialized over ...
Apr 22, 2021
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187
One of the characteristic hallmarks of Alzheimer's disease (AD) is the buildup of amyloid-beta plaques in the brain. Most therapies designed to treat AD target these plaques, but they've largely failed in clinical trials. ...
Apr 15, 2021
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230
When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell's most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power ...
Apr 7, 2021
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231
Neurons lack the ability to replicate their DNA, so they're constantly working to repair damage to their genome. Now, a new study by Salk scientists finds that these repairs are not random, but instead focus on protecting ...
Apr 1, 2021
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236
In structural biology, some molecules are so unusual they can only be captured with a unique set of tools. That's precisely how a multi-institutional research team led by Salk scientists defined how antibodies can recognize ...
Feb 18, 2021
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45
Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it. This leaves them at risk for debilitating, potentially life-threatening mood swings. ...
Jan 5, 2021
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299
If you've ever forgotten something mere seconds after it was at the forefront of your mind—the name of a dish you were about to order at a restaurant, for instance—then you know how important working memory is. This type ...
Dec 17, 2020
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69
When you touch a hot stove, your hand reflexively pulls away; if you miss a rung on a ladder, you instinctively catch yourself. Both motions take a fraction of a second and require no forethought. Now, researchers at the ...
Dec 10, 2020
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328
Salk Institute scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost of $14.4 billion annually.
Aug 19, 2020
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359
The human immune system is a finely-tuned machine, balancing when to release a cellular army to deal with pathogens, with when to rein in that army, stopping an onslaught from attacking the body itself. Now, Salk researchers ...
Jul 7, 2020
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103
