Sanford-Burnham Medical Research Institute

Oncology & Cancer

How cancer cells rewire their metabolism to survive

Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar called glucose. ...

Genetics

Diabetic fruit flies support buzz about dietary sugar dangers

Regularly consuming sucrose—the type of sugar found in many sweetened beverages—increases a person's risk of heart disease. In a study published January 10 in the journal PLOS Genetics, researchers at Sanford-Burnham ...

Medical research

How belly fat differs from thigh fat—and why it matters

Men tend to store fat in the abdominal area, but don't usually have much in the way of hips or thighs. Women, on the other hand, are more often pear-shaped—storing more fat on their hips and thighs than in the belly. Why ...

Medical research

Shifting the balance between good fat and bad fat

In many cases, obesity is caused by more than just overeating and a lack of exercise. Something in the body goes haywire, causing it to store more fat and burn less energy. But what is it? Researchers at Sanford-Burnham Medical ...

Medical research

Transplanted neural stem cells treat ALS in mouse model

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is untreatable and fatal. Nerve cells in the spinal cord die, eventually taking away a person's ability to move or even breathe. A consortium of ALS ...

Genetics

'Junk DNA' drives embryonic development

An embryo is an amazing thing. From just one initial cell, an entire living, breathing body emerges, full of working cells and organs. It comes as no surprise that embryonic development is a very carefully orchestrated process—everything ...

Oncology & Cancer

For brain tumors, origins matter

(Medical Xpress)—Since stem cells and progenitor cells are regulated by different growth factors, brain tumors arising from these cells might respond differently to different therapies. Researchers at Sanford-Burnham Medical ...

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