Seattle Children's Research Institute

Study finds new gene mutations that lead to enlarged brain size, cancer, autism, epilepsy

A research team led by Seattle Children's Research Institute has discovered new gene mutations associated with markedly enlarged brain size, or megalencephaly. Mutations in three genes, AKT3, PIK3R2 and PIK3CA, were also ...

Genetics created Jun 29, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Adolescents and young adults with mental health disorders at risk of long-term opioid use

Long-term use and abuse of opioid painkillers, such as OxyContin and Vicodin, has markedly increased in the United States in the last two decades. Of note, prescription opioids constitute 86.9 percent of prescription drug ...

Medications created Jun 06, 2012 | popularity 3 / 5 (2) | comments 0

Combating a crisis: Global burden of preterm birth can be reduced if critical actions are taken

New surveys of researchers and funders reveal a lack of consensus regarding researching and developing interventions to prevent prematurity and stillbirth, according to an article published in the American Journal of Obstetrics an ...

Obstetrics & gynaecology created Nov 06, 2012 | popularity not rated yet | comments 0

Researchers pinpoint genetic pathway of rare facial malformation in children

Researchers at Seattle Children's Research Institute and their collaborators have discovered a pair of defective genes that cause a rare congenital malformation syndrome that can make it impossible for the ...

Pediatrics created May 03, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Web-based tool helps parents improve on kids' asthma treatment

Asthma is the most common chronic illness in adolescents and children, affecting an estimated seven million children up to the age of 17 in the United States. The burden of asthma on children is substantial: kids with asthma ...

Immunology created Jun 13, 2012 | popularity not rated yet | comments 1