The Scripps Research Institute

Neuroscience

Discovery illuminates how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form within and kill brain cells ...

Medications

Search for safer pain relief advances with new compounds

Scientists at Scripps Research in Florida have created a collection of new pain-relieving compounds, that like morphine and other drugs, provide relief via activation of opioid receptors, but without inducing many dangerous ...

Alzheimer's disease & dementia

Brain cholesterol regulates Alzheimer's plaques, study reveals

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

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