Thomas Jefferson University

Medical research

Searching for better treatments for irritated tendons

When tendons get irritated it can lead to a serious condition called tendinosis—a common class of sports and workplace injuries—which is also common in older individuals. It can take many weeks of rest for tendon irritation ...

Oncology & Cancer

Potential treatment for cancer in butterfly disease

Children with the severe skin disease, recessive dystrophic epidermolysis bullosa (RDEB), also known as butterfly disease, often develop an aggressive and fatal skin cancer by early adulthood. Now an international team of ...

Medical research

New role for death molecule

Cellular death is vital for health. Without it, we could develop autoimmune diseases or cancers. But a cell's decision to self-destruct is tightly regulated, so that it only happens to serve the best interests of the body. ...

Diseases, Conditions, Syndromes

How fibrosis develops in butterfly syndrome patients

Children with a grave skin disorder known as butterfly syndrome develop severe and chronic blisters. Fibrosis, the thickening and scarring of connective tissues, is a major complication of the disease. Not only can fibrosis ...

Medical research

Blocking toxic-protein production in ALS

Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated sequences to ...

Oncology & Cancer

'Christmas berry' plant compound could fight Uveal melanoma

Doctors diagnose about 2000 adults with uveal melanoma, a cancer of the eye, every year. In half of cases, the disease metastasizes to the liver. For these patients treatment options are scarce. Researchers at the Sidney ...

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