Thomas Jefferson University

Oncology & Cancer

CAR-T immunotherapy could be improved to kill solid tumors

Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer. Chief among cancer immunotherapies is a treatment known as CAR-T, or chimeric antigen receptor ...

Medical research

Drug cocktail reduces aging-associated disc degeneration

Chronic back pain affects upwards of 15 million adults in the US, racking up billions in healthcare costs and lost work days. Degeneration of the discs that cushion and support vertebrae, a common occurrence of aging, is ...

Psychology & Psychiatry

Caring for the physical health of those with mental illness

People who struggle with serious mental illnesses are more likely to die early—about 10 to 30 years early—than those without mental illness from any cause. Many factors contribute to this disparity including poor access ...

Health

Vaping increases susceptibility to coronavirus in mice

The use of e-cigarettes, or vaping, causes serious damage to the lungs. After the novel coronavirus responsible for the respiratory disease COVID-19 emerged last year, there have been ongoing concerns about how vaping might ...

Neuroscience

Distinctive inflammatory signature found in a genetic form of ALS

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative disease that strikes nearly 5,000 people in the U.S. every year. About 10% of ALS cases are inherited or familial, often caused ...

Neuroscience

Examining the value of lumbar spine surgery

Since the 1990s the rate of spinal fusion to treat lower back pain has been on the rise. A new prospective clinical study published in the journal Neurosurgery, the official journal of the Congress of Neurological Surgeons, ...

Psychology & Psychiatry

Imposter syndrome is common among high achievers in med school

Imposter syndrome is a considerable mental health challenge to many throughout higher education. It is often associated with depression, anxiety, low self-esteem and self-sabotage and other traits. Researchers at the Sidney ...

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