Thomas Jefferson University

Cardiology

Treatment for underdiagnosed cause of debilitating chest pain

Patients who arrive at the hospital with heart-attack-like symptoms have had little recourse for their chest pain if scans came back clear, with no signs of blocked coronary arteries. Some of these cases are caused by a little-known ...

Cardiology

In heart failure, a stronger heart could spell worse symptoms

Heart failure patients fall into two general categories: those with weaker hearts, and those with stronger, but stiffer hearts that continue to eject the normal volume of blood with every beat. Although their hearts have ...

Oncology & Cancer

How melanoma evades targeted therapies

Melanoma is the leading cause of death from skin cancer. Many patients develop metastatic disease that spreads to other parts of the body. One commonly used targeted therapy for metastatic melanomas works by attacking melanomas ...

Medical research

Study opens new therapeutic avenue for mitochondria malfunction

A surprising offender has been emerging to drive the progression of Parkinson's, Alzheimer's, Huntington's and other neurodegenerative diseases: calcium. Calcium controls the production of fuel in mitochondria, the cell's ...

Neuroscience

Seizures begin with a muffle

Some patients describe epileptic seizures like an earthquake from within, starting slow and growing without their control. To a brain researcher, seizures are an electrical firestorm of neuronal activation in the brain. Now, ...

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