Thomas Jefferson University

Immunology

Cytokine may play a major role in multiple sclerosis

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving. These chemicals, called cytokines, drive the ...

Neuroscience

Stabilizing neuronal branching for healthy brain circuitry

Neurons form circuits in our brain by creating tree-like branches to connect with each other. Newly forming branches rely on the stability of microtubules, a railway-like system important for the transport of materials in ...

Immunology

Can antibiotics cause autoimmunity?

The code for every gene includes a message at the end of it that signals the translation machinery to stop. Some diseases, such as cystic fibrosis and Duchenne muscular dystrophy, can result from mutations that insert this ...

Oncology & Cancer

New 'Achilles' heel' in breast cancer: tumor cell mitochondria

Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast ...

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