Thomas Jefferson University
Researchers capture major chemotherapeutic target in complex with DNA damage
A new study published in Science May 11 is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other ...
Medical research
May 10, 2012 |
4.7 / 5 (3) |
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Blocking crucial molecule could help treat multiple sclerosis
Reporting in Nature Immunology, Jefferson neuroscientists have identified a driving force behind autoimmune diseases such as multiple sclerosis (MS), and suggest that blocking this cell-signaling molecule is the first step i ...
Medical research
Apr 24, 2011 |
4.5 / 5 (4) |
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Researchers discover new pathways that drive metastatic prostate cancer
Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical In ...
Cancer
Dec 21, 2012 |
5 / 5 (1) |
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Promising drug slows down advance of Parkinson's disease and improves symptoms
Treating Parkinson's disease patients with the experimental drug GM1 ganglioside improved symptoms and slowed their progression during a two and a half-year trial, Thomas Jefferson University researchers report in a new study ...
Parkinson's & Movement disorders
Nov 29, 2012 |
5 / 5 (2) |
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Brazilian mediums shed light on brain activity during a trance state
Researchers at Thomas Jefferson University and the University of Sao Paulo in Brazil analyzed the cerebral blood flow (CBF) of Brazilian mediums during the practice of psychography, described as a form of writing whereby ...
Neuroscience
Nov 16, 2012 |
4.3 / 5 (13) |
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Loss of protective heart failure protein linked to critical limb ischemia
Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published ...
Medical research
Oct 10, 2012 |
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Physician's empathy directly associated with positive clinical outcomes, confirms large study
Patients of doctors who are more empathic have better outcomes and fewer complications, concludes a large, empirical study by a team of Thomas Jefferson University and Italian researchers who evaluated relationships between ...
Health
Sep 10, 2012 |
4.7 / 5 (3) |
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How aging normal cells fuel tumor growth and metastasis
It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive.
Cancer
Jun 14, 2012 |
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HIV drug may slow down metastatic breast cancer
The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue ...
Cancer
Jun 06, 2012 |
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Stronger intestinal barrier may prevent cancer in the rest of the body, new study suggests
A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests.
Immunology
Feb 21, 2012 |
5 / 5 (1) |
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Curry spice component may help slow prostate tumor growth
Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers ...
Cancer
Feb 10, 2012 |
4.5 / 5 (10) |
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Drugs targeting chromosomal instability may fight a particular breast cancer subtype
Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...
Cancer
Feb 06, 2012 |
5 / 5 (1) |
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Obesity and cancer screening: Do race and gender also play a role?
Researchers in Family and Community Medicine at Thomas Jefferson University recently found that obesity was linked to higher rates of prostate cancer screening across all races/ethnic differences and lower rates of cervical ...
Health
Jan 09, 2012 |
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Researchers mirror human response to bacterial infection and resolution in mice
Imitating human diseases using an animal model is a difficult task, but Thomas Jefferson University researchers have managed to come very close.
Medical research
Dec 14, 2011 |
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New 'Achilles' heel' in breast cancer: tumor cell mitochondria
Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast ...
Cancer
Dec 01, 2011 |
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