University of California, San Francisco

Genetics

Infant gene therapy is a breakthrough for Artemis-SCID patients

Ten young children born without functioning immune systems and lacking the ability to fight infections are on track for healthier lives thanks to a new gene therapy treatment pioneered at UC San Francisco, reports a Dec. ...

Oncology & Cancer

Rethinking how cancer cells evade targeted therapy

Glioblastomas (GBMs) are incurable brain tumors with a prognosis of about one-and-a half years on average. They are highly resistant to treatment and have defied all attempts at precision therapy.

Medical research

During sleep, brain regions synchronize to create motor memory

When the Golden State Warriors' Steph Curry makes a free throw, his brain draws on motor memory. Now researchers at UC San Francisco (UCSF) have shown how this type of memory is consolidated during sleep, when the brain processes ...

Oncology & Cancer

Killing pancreatic cancer with T cells that supercharge themselves

Scientists at UC San Francisco (UCSF) have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells. The immunotherapy eliminated melanoma and pancreatic cancer in mice without ...

Medical research

Cellular 'glue' to regenerate tissues, heal wounds, regrow nerves

Researchers at UC San Francisco (UCSF) have engineered molecules that act like "cellular glue," allowing them to direct in precise fashion how cells bond with each other. The discovery represents a major step toward building ...

Psychology & Psychiatry

Screen time linked to OCD in US preteens

During the holidays, kids often spend more time on screens, leaving parents to wonder: Is it causing harm? Possibly.

Neuroscience

Down syndrome, like Alzheimer's, is a double-prion disorder

The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. ...

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