University of Chicago Medical Center

Oncology & Cancer

Old drugs bring new hope to a cancer that lacks precision therapy

An estimated 15 to 20 percent of all breast cancer patients are "triple negative." These unfortunate women lack three crucial treatment targets—the estrogen receptor, the progesterone receptor and human epidermal growth ...

Neuroscience

How the brain responds to texture

Our hands and fingertips are amazingly sensitive to texture. We can easily distinguish coarse sandpaper from smooth glass, but we also pick up more subtle differences across a wide range of textures, like the slick sheen ...

Oncology & Cancer

Nullifying protein YTHDF1 enhances anti-tumor response

Cancer immunotherapy—an approach that removes the barriers that protect cancer cells from a patient's immune system—has revolutionized the treatment of many cancer types. About 40 percent of melanoma patients, for example, ...

Cardiology

Non-coding genetic variant could improve key vascular functions

Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 ...

Genetics

Gene therapy via skin protects mice from lethal cocaine doses

There are no approved medications to treat either cocaine addiction or overdose. Frequent users tend to become less and less sensitive to the drug, leading to stronger or more frequent doses. The typical result is addiction. ...

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