University of North Carolina Health Care
Scientists use luminescent mice to track cancer and aging in real-time
In a study published in the January 18 issue of Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth ...
Medical research
Jan 17, 2013 |
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Cervical cancer screening in less-developed areas should be tailored to local conditions
The best approach to detecting cervical cancer in HIV-positive women living in research limited countries such as those in Sub-Saharan Africa combines commonly used testing methods tailored to local levels of development ...
Cancer
Jan 14, 2013 |
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Sublingual immunotherapy shows promise as treatment for peanut allergy
Peanuts are one of the most common triggers of severe food-induced allergic reactions, which can be fatal, and the prevalence of peanut allergy is increasing. However, there is currently no clinical treatment available for ...
Immunology
Jan 07, 2013 |
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Risk genes for Alzheimer's and mental illness linked to brain changes at birth
Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer's disease, schizophrenia, and autism can also be seen in the brain scans of newborns.
Neuroscience
Jan 02, 2013 |
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Team uncovers new insight into cell development and cancer
Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute ...
Cancer
Dec 27, 2012 |
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New findings in the search for genetic clues to insulin production
In research published online Dec. 23, 2012 in the journal Nature Genetics, scientists have found three new and relatively rare genetic variants that influence insulin production, offering new clues about ...
Genetics
Dec 23, 2012 |
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Gene therapy cocktail shows promise in long-term clinical trial for rare fatal brain disorder
Results of a clinical trial that began in 2001 show that a gene therapy cocktail conveyed into the brain by a molecular special delivery vehicle may help extend the lives of children with Canavan disease, a rare and fatal ...
Medical research
Dec 19, 2012 |
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Researchers discover how hepatitis C virus reprograms human liver cells
Hepatitis C virus has evolved to invade and hijack the basic machinery of the human liver cell to ensure its survival and spread. Researchers at the University of North have discovered how hepatitis C binds ...
Diseases, Conditions, Syndromes
Dec 18, 2012 |
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Study paves way to design drugs aimed at multiple protein targets at once
An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively ...
Medical research
Dec 12, 2012 |
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New mechanism for cancer progression discovered
The protein Ras plays an important role in cellular growth control. Researchers have focused on the protein because mutations in its gene are found in more than 30 percent of all cancers, making it the most prevalent human ...
Cancer
Nov 27, 2012 |
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Study justifies L-DOPA therapy for Angelman syndrome
Last year a clinical trial of L-DOPA—a mainstay of Parkinson's disease therapy—was launched for Angelman syndrome, a rare intellectual disorder that shares similar motor symptoms such as tremors and difficulty ...
Medical research
Nov 12, 2012 |
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Head-to-head trial of two diabetes drugs yields mixed results
A direct, head-to-head comparison of two of the newer treatments available for type 2 diabetes yielded mixed results.
Diabetes
Nov 06, 2012 |
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Patient-reported outcomes essential to comparative effectiveness research
Patient-reported outcomes should be a standard part of evaluating the comparative effectiveness of cancer treatments, according to recommendations put forward by a multi-institution research group.
Cancer
Oct 16, 2012 |
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Informatics approach helps doctors, patients make sense of genome data
The cost of sequencing the entire human genome, or exome – the regions of the genome that are translated into proteins that affect cell behavior – has decreased significantly, to the point where the cost of looking at ...
Genetics
Sep 20, 2012 |
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Genetically-engineered preclinical models predict pharmacodynamic response
New cancer drugs must be thoroughly tested in preclinical models, often in mice, before they can be offered to cancer patients for the first time in phase I clinical trials. Key components of this process include pharmacokinetic ...
Cancer
Sep 19, 2012 |
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