University of Pennsylvania School of Medicine

New universal platform for cancer immunotherapy developed

(Medical Xpress) -- Researchers from the Perelman School of Medicine at the University of Pennsylvania report this month in Cancer Research a universal approach to personalized cancer therapy based on T c ...

Cancer created Mar 05, 2012 | popularity 5 / 5 (9) | comments 0 | with audio podcast

A million chances to save a life: Penn Medicine crowdsourcing contest maps lifesaving AEDs in Philadelphia

Would you be able to find an automated external defibrillator if someone's life depended on it? Despite an estimated one million AEDs scattered around the United States, the answer, all too often when people suffer sudden ...

Cardiology created Feb 24, 2012 | popularity not rated yet | comments 0

Study finds new member of the breast-cancer gene network

The infamous BRCA genes do not act alone in causing cancer; there is a molecular syndicate at work preventing the way cells normally repair breaks in DNA that is at the root of breast cancer. But finding all ...

Cancer created Feb 22, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Revising the 'textbook' on liver metabolism offers new targets for diabetes drugs

A team led by researchers from the Institute for Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine, University of Pennsylvania, has overturned a "textbook" view of what the body does after a meal. ...

Diabetes created Feb 21, 2012 | popularity 5 / 5 (1) | comments 0

New combo of chemo and well-known malaria drug delivers double punch to tumors

Blocking autophagy -- the process of "self-eating" within cells -- is turning out to be a viable way to enhance the effectiveness of a wide variety of cancer treatments.

Cancer created Feb 19, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Four-week vaccination regimen knocks out early breast cancer tumors, researchers find

Researchers at the Perelman School of Medicine at the University of Pennsylvania report that a short course of vaccination with an anti-HER2 dendritic cell vaccine made partly from the patient's own cells triggers a complete ...

Cancer created Jan 30, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Sleep problems increase risk for cardiovascular disease, diabetes and obesity, study shows

(Medical Xpress) -- People who suffer from sleep disturbances are at major risk for obesity, diabetes, and coronary artery disease, according to new research from the Perelman School of Medicine at the University of Pennsylvania. ...

Health created Jan 20, 2012 | popularity 1 / 5 (1) | comments 1 | with audio podcast

Gender differences in liver cancer risk explained by small changes in genome

Men are four times more likely to develop liver cancer compared to women, a difference attributed to the sex hormones androgen and estrogen. Although this gender difference has been known for a long time, ...

Cancer created Jan 19, 2012 | popularity not rated yet | comments 0

Metastasis of pancreatic cancer in action

Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania, and Andrew Rhim, MD, a Gastroenterology Fellow in the ...

Cancer created Jan 19, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Concurrent treatment for type 2 diabetes and depression significantly improves both conditions

(Medical Xpress) -- Patients simultaneously treated for both Type 2 diabetes and depression improve medication compliance and significantly improve blood sugar and depression levels compared to patients receiving usual care, ...

Health created Jan 10, 2012 | popularity not rated yet | comments 0

Researchers shorten time for manufacturing of personalized ovarian cancer vaccine

(Medical Xpress) -- Researchers from the Perelman School of Medicine at the University of Pennsylvania are in the midst of testing a personalized, dendritic cell vaccine in patients with recurrent ovarian, primary peritoneal ...

Cancer created Dec 26, 2011 | popularity 3.5 / 5 (2) | comments 0 | with audio podcast

Novel immuno-gene therapy shows promise for the treatment of rare, deadly form of cancer

(Medical Xpress) -- Researchers at the Perelman School of Medicine at the University of Pennsylvania report promising new results from a small clinical trial using an immune-system-based gene therapy for treating advanced ...

Cancer created Dec 16, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New study shows how B cells may generate antibodies after vaccination

Steve Reiner, MD, professor of Medicine, and Burton Barnett, a doctoral student in the Reiner lab at the Perelman School of Medicine at the University of Pennsylvania, have shown how immune cells, called B ...

Medical research created Dec 15, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Reprogramming brain cells important first step for new Parkinson's therapy, study finds

(Medical Xpress) -- In efforts to find new treatments for Parkinson’s Disease (PD), researchers from the Perelman School of Medicine at the University of Pennsylvania have directly reprogrammed astrocytes, ...

Medical research created Dec 13, 2011 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

HIV drug reduces graft-versus-host disease in stem cell transplant patients

An HIV drug that redirects immune cell traffic appears to significantly reduce the dangerous complication graft-versus-host disease (GvHD) in blood cancer patients following allogeneic stem cell transplantation (ASCT), according ...

Medical research created Dec 13, 2011 | popularity not rated yet | comments 1