University of Pennsylvania School of Medicine

Black and Hispanic patients less likely to complete substance abuse treatment, study shows

Roughly half of all black and Hispanic patients who enter publicly funded alcohol treatment programs do not complete treatment, compared to 62 percent of white patients, according to a new study from a team of researchers ...

Addiction created Jan 07, 2013 | popularity 4 / 5 (1) | comments 0

Study: Most-used diabetes drug works in different way than previously thought

A team, led by senior author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Medicine, with the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University ...

Diabetes created Jan 06, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Team mimicking a natural defense against malaria to develop new treatments

(Medical Xpress)—One of the world's most devastating diseases is malaria, responsible for at least a million deaths annually, despite global efforts to combat it.  Researchers from the Perelman School ...

Medical research created Dec 27, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Immune system changes may drive aggressiveness of recurrent tumors

Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease. The ...

Cancer created Dec 27, 2012 | popularity not rated yet | comments 1 | with audio podcast

MRI can screen patients for Alzheimer's disease or frontotemporal lobar degeneration

When trying to determine the root cause of a person's dementia, using an MRI can effectively and non-invasively screen patients for Alzheimer's disease or Frontotemporal Lobar Degeneration (FTLD), according to a new study ...

Alzheimer's disease & dementia created Dec 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports

(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author ...

Cancer created Dec 20, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Alzheimer's patients with non-spousal caregivers are less likely to participate in clinical trials

People with Alzheimer's disease are less likely to participate in a clinical trial if they have non-spouse caregivers, according to a study by a team of researchers including the Perelman School of Medicine at the University ...

Alzheimer's disease & dementia created Dec 19, 2012 | popularity not rated yet | comments 0

Resistance to cocaine addiction may be passed down from father to son, study shows

Research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, ...

Neuroscience created Dec 16, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Leukemia patients remain in remission more than two years after engineered T cell therapy

Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the therapy, which was pioneered by scientists in the ...

Cancer created Dec 10, 2012 | popularity 5 / 5 (2) | comments 0

'Resistance' to low-dose aspirin therapy extremely rare, study finds

(Medical Xpress)—Roughly one-fifth of Americans take low-dose aspirin every day for heart-healthy benefits. But, based on either urine or blood tests of how aspirin blocks the stickiness of platelets ...

Cardiology created Dec 05, 2012 | popularity not rated yet | comments 0 | with audio podcast

Protected 'power naps' prove helpful for doctors in training to fight fatigue

New research from the Perelman School of Medicine at the University of Pennsylvania and the Philadelphia VA Medical Center indicates that the implementation of protected sleep periods for residents who are assigned to overnight ...

Health created Dec 04, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study finds residents believe vacant land threatens community, physical and mental health

As public health researchers continue efforts to understand the effects of neighborhood conditions on health, residents themselves can provide valuable insights regarding public health issues and potential solutions. A new ...

Health created Nov 30, 2012 | popularity 4 / 5 (1) | comments 0

Molecular root of 'exhausted' T cells in chronic viral infection

When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system ...

Medical research created Nov 29, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Pathway identified in human lymphoma points way to new blood cancer treatments

A pathway called the "Unfolded Protein Response," or UPR, a cell's way of responding to unfolded and misfolded proteins, helps tumor cells escape programmed cell death during the development of lymphoma.

Cancer created Nov 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Parkinson's disease protein causes disease spread and neuron death in healthy animals

Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease. ...

Parkinson's & Movement disorders created Nov 15, 2012 | popularity 5 / 5 (6) | comments 1 | with audio podcast