University of Pennsylvania School of Medicine
Tension on gut muscles induces cell invasion in zebrafish intestine, mimicking cancer metastasis
The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering ...
Cancer
Sep 07, 2012 |
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Alzheimer's experts provide strategic roadmap to tackle the disease
This week, a strategic roadmap to help to the nation's health care system cope with the impending public health crisis caused Alzheimer's disease and related dementia will be published in Alzheimer's & Dementia: The Journal of ...
Alzheimer's disease & dementia
Sep 07, 2012 |
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Penn Medicine physician offers model for teaching future physicians value-based care
(Medical Xpress)—Despite the national consensus on the need to improve the value of health care while reducing unnecessary spending, teaching hospitals often struggle to design curricula to train future physicians to deliver ...
Other
Aug 29, 2012 |
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Diabetes drugs taken by over 15 million Americans raises risk of bladder cancer
A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute. Researchers from the Perelman School of Med ...
Medications
Aug 13, 2012 |
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New FDA program adds to tools to curb opiod abuse in United States
A new risk management plan from the U.S. Food and Drug Administration to help clinicians properly prescribe drugs with addiction potential aims to help reduce the growing epidemic of opioid abuse in the United States. With ...
Addiction
Aug 01, 2012 |
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Benefits of HIV drugs rise -- but less than previously believed, study shows
The percentage of HIV patients taking antiretroviral drugs who experienced the full benefit of the drugs jumped from 45 percent of 72 percent during the past decade, a figure that is lower than previous estimates. The findings, ...
HIV & AIDS
Jul 22, 2012 |
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Anti-tau drug improves cognition, decreases tau tangles in Alzheimer's disease models
While clinical trial results are being released regarding drugs intended to decrease amyloid production - thought to contribute to decline in Alzheimer's disease - clinical trials of drugs targeting other disease proteins, ...
Alzheimer's disease & dementia
Jul 19, 2012 |
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Penn expert addresses ethical implications of testing for Alzheimer's disease risk
Diagnostic tests are increasingly capable of identifying plaques and tangles present in Alzheimer's disease, yet the disease remains untreatable. Questions remain about how these tests can be used in research studies examining ...
Alzheimer's disease & dementia
Jul 17, 2012 |
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HIV drug reduces graft-vs.-host disease in bone marrow transplant patients
An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman ...
Immunology
Jul 11, 2012 |
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For cardiac stenting procedures, wrist access offers cost saving benefits over groin access, study shows
(Medical Xpress) -- In the United States, radial artery (wrist) catheterization is performed in the minority of diagnostic angiograms and cardiac stenting procedures despite the benefits it offers to patients in terms of ...
Cardiology
Jul 09, 2012 |
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Gene expression test identifies low-risk thyroid nodules
A new test can be used to identify low-risk thyroid nodules, reducing unnecessary surgeries for people with thyroid nodules that have indeterminate results after biopsy. The results of the multi-center trial, which includes ...
Surgery
Jun 25, 2012 |
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Innovative, automated strategies to engage patients at home are key to improving health outcomes
In a Perspective piece published Online First this week in the New England Journal of Medicine, a group of researchers from the Perelman School of Medicine at the University of Pennsylvania propose a multi-pronged approa ...
Health
Jun 20, 2012 |
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Regional anesthesia reduces complications and death for hip fracture patients
In a study of more than 18,000 patients having surgery for hip fracture, researchers at the Perelman School of Medicine at the University of Pennsylvania found that the use of regional anesthesia versus general anesthesia, ...
Diseases, Conditions, Syndromes
Jun 20, 2012 |
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Psoriasis increases risk of diabetes: study
Psoriasis is an independent risk for Type 2 Diabetes, according to a new study by researchers with the Perelman School of Medicine at the University of Pennsylvania, with the greatest risk seen in patients with severe psoriasis. ...
Diseases, Conditions, Syndromes
Jun 18, 2012 |
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Brothers in arms: Commensal bacteria help fight viruses
Healthy humans harbor an enormous and diverse group of bacteria and other bugs that live within their intestines. These microbial partners provide beneficial aid in multiple ways – from helping digest ...
Immunology
Jun 18, 2012 |
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