University of Pennsylvania

Medical research

Low-calorie diet enhances intestinal regeneration after injury

Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most ...

Medical research

Nerve repair, with help from stem cells

A new approach to repairing peripheral nerves marries the regenerating power of gingiva-derived mesenchymal stem cells with a biological scaffold to enable the functional recovery of nerves following a facial injury, according ...

Neuroscience

HIV/AIDS drugs interfere with brain's 'insulation,' study shows

Antiretroviral therapies, or ART, have enabled people with HIV and AIDS to live much longer lives, transforming what was considered a death sentence into a chronic condition. Yet concerns for these patients remain. Up to ...

Medical research

Intervening to stop bone loss

Bone remodeling in the body involves a balancing act between osteoblasts, cells that build bone, and osteoclasts, cells that break it down. Diseases such as osteoporosis, arthritis, and periodontitis involve bone loss, and ...

Neuroscience

Neurons coordinate to fine-tune motor control

Whether it is playing a piano sonata or acing a tennis serve, the brain needs to orchestrate precise, coordinated control over the body's many muscles. Moreover, there needs to be some kind of feedback from the senses should ...

Immunology

Gut cells sound the alarm when parasites invade

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder. Knowing more about these early stages of pathogen ...

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