University of Pittsburgh Schools of the Health Sciences

Transplant experts challenge assumption, describe pathway that leads to organ rejection

Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in ...

Medical research created May 15, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Doctor's choice of words may influence family's decision to permit CPR in critically ill

A physician's choice of words when talking with family members about whether or not to try cardiopulmonary resuscitation (CPR) if a critically ill patient's heart stops may influence the decision, according to a study by ...

Other created May 09, 2013 | popularity not rated yet | comments 0

Discovery holds potential in destroying drug-resistant bacteria

Through the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells. ...

Medical research created May 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Breast milk ingredient could prevent necrotizing enterocolitis—deadly intestinal problem in preemies

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, according to researchers at the University of ...

Diseases, Conditions, Syndromes created May 06, 2013 | popularity not rated yet | comments 2 | with audio podcast

Team finds melatonin delays ALS symptom onset and death in mice

Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to a new study by researchers at ...

Neuroscience created Apr 25, 2013 | popularity not rated yet | comments 0

Mild blast injury causes molecular changes in brain akin to Alzheimer, team says

A multicenter study led by scientists at the University of Pittsburgh School of Medicine shows that mild traumatic brain injury after blast exposure produces inflammation, oxidative stress and gene activation patterns akin ...

Neuroscience created Apr 24, 2013 | popularity 4.5 / 5 (2) | comments 0

Recipe for large numbers of stem cells requires only one ingredient

Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...

Medical research created Apr 17, 2013 | popularity 5 / 5 (6) | comments 1 | with audio podcast

Study finds immunity protein that ramps up inflammation, and agents that can block it

Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...

Immunology created Mar 31, 2013 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Researchers find novel mechanism regulating replication of insulin-producing beta cells

Bringing scientists a step closer to new treatments for diabetes, researchers at the University of Pittsburgh School of Medicine and The Mount Sinai Medical Center have discovered a novel mechanism that regulates the replication ...

Diabetes created Mar 26, 2013 | popularity 5 / 5 (1) | comments 0

First 'breathing lung' transplant on East Coast using OCS lung

UPMC surgeons have performed a "breathing lung" transplant using a portable machine that provides a constant supply of blood and nutrients to the donor organs, which doctors say has the potential to keep them healthier and ...

Other created Mar 14, 2013 | popularity not rated yet | comments 0

Study examines cost-effectiveness of medicare drug plans in schizophrenia and bipolar disorder

A new study published online today in the American Journal of Managed Care found that in Medicare Part D, generic drug coverage was cost-saving compared to no coverage in bipolar disorder and schizophrenia, while also improv ...

Health created Feb 20, 2013 | popularity not rated yet | comments 0

Physical activity linked to lower rates of depression in bariatric surgery patients

Adults undergoing bariatric surgery who are more physically active are less likely to have depressive symptoms and to have recently received medication or counseling for depression or anxiety than their less active counterparts, ...

Psychology & Psychiatry created Feb 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

Large study shows substance abuse rates higher in teenagers with ADHD

A new study published online in the Journal of the American Academy of Child and Adolescent Psychiatry revealed a significantly higher prevalence of substance abuse and cigarette use by adolescents with attention deficit hypera ...

Attention deficit disorders created Feb 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Team describes findings from BCI study in spinal cord-injured man in PLoS One

Researchers at the University of Pittsburgh School of Medicine and UPMC describe in PLoS ONE how an electrode array sitting on top of the brain enabled a 30-year-old paralyzed man to control the movement of a character on a c ...

Neuroscience created Feb 08, 2013 | popularity not rated yet | comments 0

Researchers reveal mechanism to halt cancer cell growth, discover potential therapy

University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.

Cancer created Feb 04, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast