University of Pittsburgh Schools of the Health Sciences
A shot of young stem cells made rapidly aging mice live longer and healthier
Mice bred to age too quickly seemed to have sipped from the fountain of youth after scientists at the University of Pittsburgh School of Medicine injected them with stem cell-like progenitor cells derived from the muscle ...
Medical research
Jan 03, 2012 |
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Recipe for large numbers of stem cells requires only one ingredient
Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...
Medical research
Apr 17, 2013 |
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Scientists identify agent that can block fibrosis of skin, lungs
Researchers at the University of Pittsburgh School of Medicine have identified an agent that in lab tests protected the skin and lungs from fibrosis, a process that can ultimately end in organ failure and even death because ...
Medical research
May 30, 2012 |
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Study finds immunity protein that ramps up inflammation, and agents that can block it
Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...
Immunology
Mar 31, 2013 |
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Transplant experts challenge assumption, describe pathway that leads to organ rejection
Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in ...
Medical research
May 15, 2013 |
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Cell membrane proteins could provide targets for broader vaccines
Vaccines with broader reach might be made by stimulating specialized immune cells to recognize foreign cell membrane proteins that are shared across bacterial species, say researchers from Children's Hospital of Pittsburgh ...
Medical research
Dec 22, 2011 |
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Researchers use genomics to identify a molecular-based treatment for a viral skin cancer
Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...
Cancer
May 09, 2012 |
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Pitt scientists developing universal flu vaccine in partnership with Sanofi Pasteur
(Medical Xpress) -- A vaccine strategy that protects against all strains of seasonal influenza and avoids the need for annual vaccination is the ultimate goal of a research collaboration between the University of Pittsburgh ...
Medications
Jul 24, 2012 |
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Vaccine triggers immunity to prevent colon cancer
(Medical Xpress)—A first-of-its-kind vaccine developed by University of Pittsburgh Cancer Institute (UPCI) researchers successfully prompted the immune system to respond to early indications of colon cancer in people at ...
Cancer
Jan 08, 2013 |
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Exceptional cognitive and physical health in old age leaves immunological fingerprint
Exceptional cognitive and physical function in old age leaves a tell-tale immunologic fingerprint, say researchers at the University of Pittsburgh and Children's Hospital of Pittsburgh of UPMC. Likewise, older adults who ...
Medical research
Oct 21, 2011 |
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Researchers reveal mechanism to halt cancer cell growth, discover potential therapy
University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.
Cancer
Feb 04, 2013 |
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Mild blast injury causes molecular changes in brain akin to Alzheimer, team says
A multicenter study led by scientists at the University of Pittsburgh School of Medicine shows that mild traumatic brain injury after blast exposure produces inflammation, oxidative stress and gene activation patterns akin ...
Neuroscience
Apr 24, 2013 |
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Cell-signaling pathway has key role in development of gestational diabetes
Researchers at the University of Pittsburgh School of Medicine have identified a cell-signaling pathway that plays a key role in increasing insulin secretion during pregnancy and, when blocked, leads to the development of ...
Diabetes
Mar 16, 2012 |
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Sperm precursor cells made in the lab could one day restore male fertility
(Medical Xpress)—Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) can be coaxed into becoming precursor sperm cells, suggesting that it might be possible one day to restore fertility ...
Medical research
Aug 28, 2012 |
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Stem cell study: Male fertility can be restored after cancer treatment
An injection of banked sperm-producing stem cells can restore fertility to male primates who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and ...
Medical research
Nov 01, 2012 |
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