University of Pittsburgh Schools of the Health Sciences

Study finds immunity protein that ramps up inflammation, and agents that can block it

Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...

Immunology created Mar 31, 2013 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Stem cell study: Male fertility can be restored after cancer treatment

An injection of banked sperm-producing stem cells can restore fertility to male primates who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and ...

Medical research created Nov 01, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Targeted oxidation-blocker prevents secondary damage after traumatic brain injury

Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been ...

Neuroscience created Aug 26, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Scientists identify agent that can block fibrosis of skin, lungs

Researchers at the University of Pittsburgh School of Medicine have identified an agent that in lab tests protected the skin and lungs from fibrosis, a process that can ultimately end in organ failure and even death because ...

Medical research created May 30, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Researchers use genomics to identify a molecular-based treatment for a viral skin cancer

Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...

Cancer created May 09, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Transplant experts challenge assumption, describe pathway that leads to organ rejection

Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in ...

Medical research created May 15, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Discovery holds potential in destroying drug-resistant bacteria

Through the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells. ...

Medical research created May 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Breast milk ingredient could prevent necrotizing enterocolitis—deadly intestinal problem in preemies

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, according to researchers at the University of ...

Diseases, Conditions, Syndromes created May 06, 2013 | popularity not rated yet | comments 2 | with audio podcast

Recipe for large numbers of stem cells requires only one ingredient

Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...

Medical research created Apr 17, 2013 | popularity 5 / 5 (6) | comments 1 | with audio podcast

Physical activity linked to lower rates of depression in bariatric surgery patients

Adults undergoing bariatric surgery who are more physically active are less likely to have depressive symptoms and to have recently received medication or counseling for depression or anxiety than their less active counterparts, ...

Psychology & Psychiatry created Feb 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

Large study shows substance abuse rates higher in teenagers with ADHD

A new study published online in the Journal of the American Academy of Child and Adolescent Psychiatry revealed a significantly higher prevalence of substance abuse and cigarette use by adolescents with attention deficit hypera ...

Attention deficit disorders created Feb 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers reveal mechanism to halt cancer cell growth, discover potential therapy

University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.

Cancer created Feb 04, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Study finds 'Achilles heel' of key HIV replication protein

Researchers at the University of Pittsburgh School of Medicine may have found an "Achilles heel" in a key HIV protein. In findings published online today in Chemistry and Biology, they showed that targeting this vulnerable spot c ...

HIV & AIDS created Jan 24, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Inaccurate diagnoses of melanoma by smartphone apps could delay doctor visits, life-saving treatment

Smartphone applications that claim to evaluate a user's photographs of skin lesions for the likelihood of cancer instead returned highly variable and often inaccurate feedback, according to a study led by researchers at the ...

Cancer created Jan 16, 2013 | popularity not rated yet | comments 0 | with audio podcast

Vaccine triggers immunity to prevent colon cancer

(Medical Xpress)—A first-of-its-kind vaccine developed by University of Pittsburgh Cancer Institute (UPCI) researchers successfully prompted the immune system to respond to early indications of colon cancer in people at ...

Cancer created Jan 08, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast