UT Southwestern Medical Center

Oncology & Cancer

Team discovers broken 'brake' of cancer mutation machine

Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that creates random mutations throughout the genome that drive resistance to targeted treatments, a team led by UT Southwestern Medical ...

Diseases, Conditions, Syndromes

Protein inhibits development of COVID-19 in live animals

A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing ...

Cardiology

Research pinpoints inflammation source behind atherosclerosis

Scientists at UT Southwestern Medical Center and Children's Medical Center Dallas have discovered in mice how high cholesterol causes blood vessels to become inflamed, a necessary prerequisite for atherosclerosis—the "hardening ...

Diseases, Conditions, Syndromes

Early diagnosis of pelvic floor disorders key for health

Pelvic floor disorders (PFDs), which occur when women's pelvic floor muscles are weakened or injured, significantly affect quality of life and require surgery for hundreds of thousands in the U.S. each year. Now a study led ...

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