UT Southwestern Medical Center

Medical research

Tackling resistance to HIF2 drugs with an RNA-based therapy

Expected to be diagnosed in 2% of men and 1% of women in the U.S., kidney cancer has traditionally been one of the most challenging cancers to treat. Until 2005, only one drug had been approved by the Food and Drug Administration ...

Cardiology

Researchers use DNA analysis to diagnose subtypes of heart disease

The human heart is an intricate, complex organ and, like a car that starts sputtering, its function deteriorates for all sorts of reasons. Cardiomyopathy—any disease of the heart muscle that makes it pump blood less effectively—can ...

Oncology & Cancer

Researchers discover new molecular driver of retinoblastoma

Despite decades of medical advances, children who develop the pediatric eye cancer retinoblastoma often lose their vision or an eye due to a lack of specific, targeted therapies and a poor molecular understanding of the cancer. ...

Medical research

Shape-shifting fat cells fuel breast cancer growth

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests. The findings, published in Cell Reports, ...

Inflammatory disorders

Researchers discover new drug target for inflammatory bowel disease

A set of interacting molecules in immune cells of the gut is responsible for preventing the inflammation seen in inflammatory bowel diseases (IBD), UT Southwestern researchers report in a new study. The findings, published ...

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