UT Southwestern Medical Center

Oncology & Cancer

Cellular 'waste product' rejuvenates cancer-fighting immune cells

A new study by UT Southwestern's Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer. The finding, published ...

Genetics

Study links gene mutation to learning deficits in 'Clueless' mice

A single mutation in a gene, Kcnc3, which encodes a potassium channel in neurons, causes learning deficits in mice, UT Southwestern researchers report in a new study in PNAS. The novel mutation decreases the activity of neurons ...

Medical research

Scientists identify pathway to curb spread of brain cancer

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models. The findings, ...

Medical research

Researchers develop blood test to predict liver cancer risk

An estimated one-quarter of adults in the U.S. have nonalcoholic fatty liver disease (NAFLD), an excess of fat in liver cells that can cause chronic inflammation and liver damage, increasing the risk of liver cancer. Now, ...

Genetics

Researchers find that RNA exosome is key for B cell development

New research from UT Southwestern suggests that RNA exosomes—the cellular machines that degrade old molecules of RNA—play a key role in the development of B cells, which are critical to the immune system's ability to ...

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