Washington University School of Medicine

Medical research

Human skin cells transformed directly into motor neurons

Scientists working to develop new treatments for neurodegenerative diseases have been stymied by the inability to grow human motor neurons in the lab. Motor neurons drive muscle contractions, and their damage underlies devastating ...

Alzheimer's disease & dementia

Midlife changes in Alzheimer's biomarkers may predict dementia

Studying brain scans and cerebrospinal fluid of healthy adults, scientists have shown that changes in key biomarkers of Alzheimer's disease during midlife may help identify those who will develop dementia years later, according ...

Oncology & Cancer

Personalized melanoma vaccines marshal powerful immune response

Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of ...

Neuroscience

Human skin cells reprogrammed directly into brain cells

Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington's disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one ...

Alzheimer's disease & dementia

Rare gene variants double risk for Alzheimer's disease

A team led by researchers at Washington University School of Medicine in St. Louis has identified variations in a gene that doubles a person's risk of developing Alzheimer's disease later in life.

Medical research

A new genetic fingerprint lives in your belly

Our bodies contain far more microbial genes than human genes. And a new study suggests that just as human DNA varies from person to person, so too does the massive collection of microbial DNA in the intestine.

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