Wellcome Trust Sanger Institute

Using healthy skin to identify cancer's origins

Normal skin contains an unexpectedly high number of cancer-associated mutations, according to a study published in Science. The findings illuminate the first steps cells take towards becoming a cancer and de ...

May 21, 2015
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Patient cancer cells help to test treatments

A study, published today in Cell, demonstrates the power of organoids to capture, in three dimensions, the multiple mutations that occur in tumours. Organoids, small clusters of cells that accurately mimic ...

May 07, 2015
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Novel breast cancer gene found

A new study identifies a gene that is especially active in aggressive subtypes of breast cancer. The research suggests that an overactive BCL11A gene drives triple-negative breast cancer development and progression.

Jan 09, 2015
popularity 757 comments 0

Gene variant that dramatically reduces 'bad' lipids

In the first study to emerge from the UK10K Project's cohort of samples from the general public, scientists have identified a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. ...

Sep 16, 2014
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Mobile DNA elements restructure cancer genomes

(Medical Xpress)—Researchers have found a novel mechanism that can restructure a cancer's genome and introduce hundreds of mutations. Previously overlooked through misidentification, this mechanism, a common ...

Aug 07, 2014
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