Yale University

Medical research

Lung disease and melanoma: A common molecular mechanism?

A Yale-led team of researchers has solved a biological mystery about the common genesis of many serious diseases such as asthma and metastatic melanoma, identifying the first known pathway by which their cellular functions ...

Medical research

Immune system may have another job—combatting depression

An inflammatory autoimmune response within the central nervous system similar to one linked to neurodegenerative diseases such as multiple sclerosis (MS) has also been found in the spinal fluid of healthy people, according ...

Immunology

T cells found to require rest and maintenance

T cells, biology textbooks teach us, are the soldiers of the immune system, constantly on the ready to respond to a variety of threats, from viruses to tumors. However, without rest and maintenance T cells can die and leave ...

Health

How common gut bacteria trigger a lethal autoimmune disease

What causes the immune system, designed to protect us, to turn on the body and attack healthy cells? Common bacteria that reside in the human gut may be partly to blame, say Yale researchers, who studied the origins of a ...

Genetics

Inactive genes surprisingly common in humans

(Medical Xpress) -- Every person carries on average 100 variants that disable genes - yet very few suffer ill effects, an international team of researchers led by Yale University and Wellcome Trust Sanger Institute report ...

Diabetes

How leptin, the 'satiety hormone,' reverses diabetes

(Medical Xpress)—Treatment with leptin, the hormone associated with fullness or satiety, reverses hyperglycemia in animals models of poorly controlled type 1 (T1D) and type 2 (T2D) diabetes by suppressing the neuroendocrine ...

Diseases, Conditions, Syndromes

Wastewater predicts COVID-19 outbreaks days before diagnostic testing

By taking daily samples from the New Haven-area wastewater treatment plant, researchers have been able to track the progression of COVID-19 up to seven days before the same pattern is reported by compiled testing data from ...

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