More pregnant women taking high blood pressure drugs, yet safety unclear

September 10th, 2012 in Cardiology /

Nearly 5 percent of pregnant women are prescribed drugs to treat high blood pressure, including some drugs that aren't considered safe for mothers or their babies, according to new research in the American Heart Association's journal Hypertension.

Use of high blood pressure drugs during pregnancy is becoming increasingly common, said Brian T. Bateman, M.D., lead author and Assistant Professor of anesthesia at Harvard Medical School in Boston, Mass.

"While we know high blood pressure, or hypertension, occurs in about 6 percent to 8 percent of all pregnancies, we know little about how women and their doctors treat the condition," he said.

Researchers studied a database of more than 1 million , of whom 48,453 (4.4 percent) filled prescriptions for high during their pregnancies.

They found:

Limited information is available about which are safest and most effective for treating during pregnancy, Bateman said. In general, methyldopa and labetalol are the recommended antihypertensives for use during pregnancy. More research on which antihypertensives to prescribe during pregnancy and how to use them safely is urgently needed, he said.

"We know from reports that a number of harmful effects can occur from using ACE inhibitors or angiotensin receptor blockers, especially during the second and third trimester," Bateman said. "These drugs can cause poor growth, kidney problems and even death of the newborn. If women are taking one of these blood pressure medications and they become pregnant or plan to do so, they and their doctors should discuss treatment choices during pregnancy."

Provided by American Heart Association

"More pregnant women taking high blood pressure drugs, yet safety unclear." September 10th, 2012. http://medicalxpress.com/news/2012-09-pregnant-women-high-blood-pressure.html