Circadian rhythms orchestrate a vast number of life's processes through the activity of a 24-hour internal clock: hormone flow, blood pressure, sleep and wake cycles, and even the timing of hibernation among marmots and bears, ...
The long-sought Holy Grail for heart attack patients has been a method to regenerate healthy new tissue, but the basic building blocks required to remodel an injured heart have remained elusive—until now.
In recent years, neuroscientists have debated whether prion-like activity damages the brain in people with Parkinson's, but scientists in Japan, after an exhaustive analysis, report no evidence of misfolded, transmissable ...
Bone tissue engineering (BTE) is an evolving field at the intersection of materials science and bioengineering, focused on the development of bone substitute materials and diagnostic methods in orthopedics. At present, physicians ...
Implantable neuromodulation devices such as deep brain stimulators and vagus nerve stimulators, are widely used to treat neurological diseases. Most devices are composed of rigid probes that limit spatial resolution and increase ...
Cell-penetrating peptides (CPPs) have attracted great interest as delivery vehicles in medicine, with potential for the development of novel therapeutic agents or cosmetic products. Biological membranes are typically impermeable ...
A growing need for tissues and organs in surgical reconstruction is addressed by the promising field of tissue engineering. For instance, muscle atrophy results from severe traumatic events including deep burns and cancer, ...
Mesenchymal stem cells (MSCs) are a promising cell source, easy to harvest and differentiate into a variety of mesodermal tissues including fat, bone and cartilage in regenerative medicine. However, for in vivo implantation, ...
Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage ...
Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicates the emerging role of chondrocyte-to-osteoblast ...
