http://medicalxpress.com/arthritis-rheumatism-news/ en-us Medical Xpress provides the latest research news on Arthritis & Rheumatism, In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system makes a unique subset of antibodies that have a disease-promoting role. http://medicalxpress.com/news/2013-05-enzyme-activating-antibodies-revealed-marker-severe.html Arthritis & Rheumatism Wed, 22 May 2013 14:00:01 EST news288447305 (HealthDay)—Injections of a sugar solution appear to help relieve knee pain and stiffness related to osteoarthritis, a new study suggests. http://medicalxpress.com/news/2013-05-sugar-knee-arthritis-ease-pain.html Arthritis & Rheumatism Tue, 21 May 2013 07:30:01 EST news288336772 A novel study reports that white men and women of European descent inherit common foot disorders, such as bunions (hallux valgus) and lesser toe deformities, including hammer or claw toe. Findings from the Framingham Foot Study—the first to estimate the heritability of foot disorders in humans—appear in Arthritis Care & Research, a journal published by Wiley on behalf of the American College of Rheumatology (ACR). http://medicalxpress.com/news/2013-05-blame-parents-bunion-woes.html Arthritis & Rheumatism Mon, 20 May 2013 02:42:46 EST news288236552 Scientists at Johns Hopkins have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, they now have evidence that the bone underneath the cartilage is also a key player and exacerbates the damage. In a proof-of-concept experiment, they found that blocking the action of a critical bone regulation protein in mice halts progression of the disease. http://medicalxpress.com/news/2013-05-theory-genesis-osteoarthritis-successful-therapy.html Arthritis & Rheumatism Sun, 19 May 2013 13:10:10 EST news288172115 (HealthDay)—Compared to clinical diagnosis of synovitis, ultrasound-detected synovitis provides either improved sensitivity or specificity when used with the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria for identifying patients with a disease requiring methotrexate (MTX) treatment, according to research published in the April issue of Arthritis & Rheumatism. http://medicalxpress.com/news/2013-05-ultrasound-classification-ra.html Arthritis & Rheumatism Wed, 15 May 2013 20:30:01 EST news287860933 (HealthDay)—A genome-wide linkage scan has identified the chromosome 17p11.2-q11.2 region as the susceptibility locus for fibromyalgia, according to research published in the April issue of Arthritis & Rheumatism. http://medicalxpress.com/news/2013-05-strong-genetic-component-fibromyalgia.html Arthritis & Rheumatism Sat, 11 May 2013 03:30:02 EST news287461020 Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis, a finding that paves the way for new gene therapies that could offer relief and mobility to millions worldwide. http://medicalxpress.com/news/2013-05-discovery-fat-triggers-rheumatoid-arthritis.html Arthritis & Rheumatism Wed, 08 May 2013 08:42:27 EST news287221341 Researchers from the Royal College of Surgeons in Ireland (RCSI) have discovered that a new treatment for the inflammatory condition, Systemic Lupus Erythmstosus (SLE) could potentially benefit Irish patients who suffer from the condition. http://medicalxpress.com/news/2013-05-irish-lupus-patients-benefit-treatment.html Arthritis & Rheumatism Tue, 07 May 2013 09:07:52 EST news287136465 A team of researchers led by a Boston University Biomedical Engineer has developed a new joint lubricant that could bring longer lasting relief to millions of osteoarthritis sufferers. The new synthetic polymer supplements synovial fluid, the natural lubricant in joints, and works better than comparable treatments currently available. http://medicalxpress.com/news/2013-05-oil-joints-osteoarthritis.html Arthritis & Rheumatism Thu, 02 May 2013 16:42:33 EST news286731746 For many people who have fibromyalgia, even the thought of exercising is painful. Yet a new study from Wake Forest Baptist Medical Center shows that exercise does not worsen the pain associated with the disorder and may even lessen it over time. The findings are published in the current online issue of the journal Arthritis Care & Research. http://medicalxpress.com/news/2013-05-regular-moderate-worsen-pain-people.html Arthritis & Rheumatism Thu, 02 May 2013 13:38:20 EST news286720675 A gas associated with the smell of rotten eggs has proven to effectively reduce joint swelling, in research which could lead to advances in the treatment of arthritis. http://medicalxpress.com/news/2013-04-foul-smelling-gas-health-benefits-joint.html Arthritis & Rheumatism Mon, 29 Apr 2013 12:51:29 EST news286458682 Stems cells taken from just a few grams of body fat are a promising weapon against the crippling effects of osteoarthritis. http://medicalxpress.com/news/2013-04-stem-cells-arthritis.html Arthritis & Rheumatism Sun, 28 Apr 2013 18:50:01 EST news286392514 Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hydrogel engineered with gene modified bone marrow mesenchymal stromal cells (BMSCs). The chitosan and polyvinyl alcohol composite hydrogel containing hTGFβ-1 gene modified BMSCs was injected into rabbits with defective articular cartilage. Sixteen weeks later the defected cartilage regenerated and was proven to be hyaline cartilage. This work can be found in the January 2013 issue of Experimental Biology and Medicine. http://medicalxpress.com/news/2013-04-articular-cartilage-defects-gel-gene.html Arthritis & Rheumatism Tue, 23 Apr 2013 14:44:40 EST news285947076 (HealthDay)—Allopurinol initiators have an almost 10-fold increased risk of severe cutaneous adverse reactions (SCARs) compared with nonusers, according to a study published in the April issue of Arthritis Care & Research. http://medicalxpress.com/news/2013-04-severe-cutaneous-adverse-rxns-allopurinol.html Arthritis & Rheumatism Tue, 23 Apr 2013 13:30:02 EST news285940367 (Medical Xpress)—Scientists from The University of Manchester have identified 14 new genes which could have important consequences for future treatments of childhood arthritis. http://medicalxpress.com/news/2013-04-discovery-genes-childhood-arthritis-treatment.html Arthritis & Rheumatism Mon, 22 Apr 2013 08:05:34 EST news285836724 Number of cigarettes smoked a day and the number of years a person has smoked both increase the risk of rheumatoid arthritis (RA), finds research in BioMed Central's open access journal Arthritis Research & Therapy. The risk decreases after giving up smoking but, compared to people who have never smoked, this risk is still elevated 15 years after giving up. http://medicalxpress.com/news/2013-04-cigarettes-day-rheumatoid-arthritis.html Arthritis & Rheumatism Sun, 21 Apr 2013 20:00:01 EST news285766046 (HealthDay)—Patients with systemic lupus erythematosus (SLE) have an increased risk of spontaneous subarachnoid hemorrhage (SAH) and increased mortality after SAH, according to a study published in the April issue of Arthritis Care & Research. http://medicalxpress.com/news/2013-04-lupus-ups-spontaneous-subarachnoid-hemorrhage.html Arthritis & Rheumatism Fri, 19 Apr 2013 15:16:50 EST news285603403 A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over time, resulting in the development of osteoarthritis. The findings are published in the April issue of PLOS ONE. http://medicalxpress.com/news/2013-04-insight-osteoarthritis.html Arthritis & Rheumatism Fri, 19 Apr 2013 13:08:44 EST news285595716 (Medical Xpress)—Wearing a knee brace has been shown to "significantly improve the pain and symptoms" of a type of osteoarthritis affecting the kneecap, according to a new study. http://medicalxpress.com/news/2013-04-knee-bracing-significantly-pain-kneecap.html Arthritis & Rheumatism Fri, 19 Apr 2013 09:20:02 EST news285580865 (HealthDay)—A model including ultrasound (US) assessment of the wrist, metacarpophalangeal (MCP), ankle, and metatarsophalangeal (MTP) joints is highly sensitive for detecting B-mode and Doppler joint inflammation in patients with rheumatoid arthritis (RA), according to a study published in the April issue of Arthritis Care & Research. http://medicalxpress.com/news/2013-04-ultrasound-ids-residual-joint-inflammation.html Arthritis & Rheumatism Thu, 18 Apr 2013 14:00:13 EST news285510149 Osteoarthritis, which affects at least 20 percent of adults in the United States, leads to deterioration of cartilage, the rubbery tissue that prevents bones from rubbing together. By studying the molecular properties of cartilage, MIT engineers have now discovered how the earliest stages of arthritis make the tissue more susceptible to damage from physical activities such as running or jumping. http://medicalxpress.com/news/2013-04-earliest-stages-arthritis-high-impact-worsen.html Arthritis & Rheumatism Wed, 17 Apr 2013 15:02:16 EST news285429716 A new study published in the American College of Rheumatology (ACR) journal, Arthritis Care & Research, reveals that women with rheumatoid arthritis (RA) who were on methotrexate (MTX), a drug commonly used to reduce inflammation caused by RA, had lower rates of induced abortions compared to women with RA who were not exposed to the medication. Findings indicate that women with RA exposed to anti-tumor necrosis factor (anti-TNF) drugs may have increased abortion rates compared to unexposed women. http://medicalxpress.com/news/2013-04-medications-rheumatoid-arthritis-affect-abortion.html Arthritis & Rheumatism Tue, 16 Apr 2013 00:00:01 EST news285246115 (Medical Xpress)—One in three people with rheumatoid arthritis, regardless of their age, will fall once or more times a year, according to a new University of Manchester study. http://medicalxpress.com/news/2013-04-people-rheumatoid-arthritis-high-falls.html Arthritis & Rheumatism Thu, 11 Apr 2013 07:26:33 EST news284883987 New research suggests that patients with knee osteoarthritis (OA) who wear flat, flexible footwear (mobility shoes) had significant reduction in knee loading—the force placed upon the joint during daily activities. Results published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), show that long term use of the mobility shoes helped OA patients adapt their gait, or how they walk, which improved knee loading, even when the mobility shoes were no longer worn. http://medicalxpress.com/news/2013-04-mobility-knee-osteoarthritis.html Arthritis & Rheumatism Wed, 10 Apr 2013 00:00:01 EST news284754361 Only half of people with arthritis who had a hip or knee replacement reported a significant improvement in pain and mobility after surgery, according to a new study led by Women's College Hospital and the Institute for Clinical and Evaluative Sciences (ICES). http://medicalxpress.com/news/2013-04-patients-benefit-equally-hip-knee.html Arthritis & Rheumatism Thu, 04 Apr 2013 16:32:06 EST news284311863 (Medical Xpress)—Scientists at the University of Liverpool have found that a drug treatment administered at the earliest signs of a rare genetic disease could prevent the condition from developing in later life. http://medicalxpress.com/news/2013-04-alkaptonuria-treatment-rare-genetic-disease.html Arthritis & Rheumatism Thu, 04 Apr 2013 06:54:49 EST news284277272 Low testosterone levels may herald the subsequent development of rheumatoid arthritis in men, suggests research published online in the Annals of the Rheumatic Diseases. http://medicalxpress.com/news/2013-04-testosterone-herald-rheumatoid-arthritis-men.html Arthritis & Rheumatism Wed, 03 Apr 2013 18:30:01 EST news284227173 Think new discoveries are the bee's knees? This one is even better—this research out of Rhode Island Hospital is the mice's knees. Researchers have found that adding lubricin, a protein that our bodies naturally produce, to the fluid in our joints may reduce the risk of or even prevent osteoarthritis (OA). http://medicalxpress.com/news/2013-03-team-strategy-effectively-osteoarthritis.html Arthritis & Rheumatism Mon, 25 Mar 2013 15:00:22 EST news283435184 When you think of knee replacement surgery, you generally envision an older adult with painful arthritis. But the procedure is also used for younger patients with juvenile idiopathic arthritis (JIA) whose joints have been severely damaged by the disease. Because the surgery in younger patients is relatively rare, little data exist on the longevity of knee replacements in JIA patients. http://medicalxpress.com/news/2013-03-longevity-total-knee-younger-patients.html Arthritis & Rheumatism Wed, 20 Mar 2013 10:08:22 EST news282992878 (Medical Xpress)—Emory Orthopaedics & Spine Center is now one of a small number of clinics in the country to offer a cutting edge stem cell treatment for Osteoarthritis (OA). http://medicalxpress.com/news/2013-03-stem-cell-relieve-arthritis-pain.html Arthritis & Rheumatism Wed, 20 Mar 2013 07:30:01 EST news282982741