http://medicalxpress.com/alzheimer-dementia-news/ en-us Medical Xpress provides the latest research news on alzheimer's disease, dementia A new study looking at sleep-disordered breathing (SDB) and markers for Alzheimer's disease (AD) risk in cerebrospinal fluid (CSF) and neuroimaging adds to the growing body of research linking the two. http://medicalxpress.com/news/2013-05-apnea-alzheimer-linked.html Alzheimer's disease & dementia Sun, 19 May 2013 14:00:05 EST news288172741 (Medical Xpress)—Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved medications against MS. http://medicalxpress.com/news/2013-05-approach-treatment-ms-conditions.html Alzheimer's disease & dementia Fri, 17 May 2013 16:54:30 EST news288028433 People who have skin cancer may be less likely to develop Alzheimer's disease, according to new research published in the May 15, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. The link does not apply to melanoma, a less common but more aggressive type of skin cancer. http://medicalxpress.com/news/2013-05-skin-cancer-linked-alzheimer-disease.html Alzheimer's disease & dementia Wed, 15 May 2013 16:00:01 EST news287825399 (Medical Xpress)—Scientists at Washington University School of Medicine in St. Louis have helped identify many of the biomarkers for Alzheimer's disease that could potentially predict which patients will develop the disorder later in life. Now, studying spinal fluid samples and health data from 201 research participants at the Charles F. and Joanne Knight Alzheimer's Disease Research Center, the researchers have shown the markers are accurate predictors of Alzheimer's years before symptoms develop. http://medicalxpress.com/news/2013-05-alzheimer-markers-mental-decline.html Alzheimer's disease & dementia Tue, 14 May 2013 06:48:36 EST news287732906 A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, published May 14 in the journal Alzheimer's Research and Therapy, may pave the way to a new treatment for Alzheimer's disease in humans. http://medicalxpress.com/news/2013-05-scientists-drug-alzheimer-mice.html Alzheimer's disease & dementia Mon, 13 May 2013 20:00:01 EST news287689272 Research from the Regenstrief Institute, the Indiana University Center for Aging Research and Wishard-Eskenazi Health on medications commonly taken by older adults has found that drugs with strong anticholinergic effects cause cognitive impairment when taken continuously for as few as 60 days. A similar impact can be seen with 90 days of continuous use when taking multiple drugs with weak anticholinergic effect. http://medicalxpress.com/news/2013-05-anticholinergics-days-memory-problems-older.html Alzheimer's disease & dementia Tue, 07 May 2013 10:52:22 EST news287142734 (Medical Xpress)—A new University of Arizona study, published in the journal Neurology, suggests a possible link between elevated blood sugar levels and risk for developing Alzheimer's disease. http://medicalxpress.com/news/2013-05-link-elevated-blood-sugar-alzheimer.html Alzheimer's disease & dementia Mon, 06 May 2013 08:17:32 EST news287047034 Elderly patients who receive anesthesia are no more likely to develop long-term dementia or Alzheimer's disease than other seniors, according to new Mayo Clinic research. The study analyzed thousands of patients using the Rochester Epidemiology Project—which allows researchers access to medical records of nearly all residents of Olmsted County, Minn.—and found that receiving general anesthesia for procedures after age 45 is not a risk factor for developing dementia. The findings were published Wednesday, May 1, online in Mayo Clinic Proceedings. http://medicalxpress.com/news/2013-04-link-anesthesia-dementia-elderly.html Alzheimer's disease & dementia Wed, 01 May 2013 00:10:01 EST news286564133 Scientists funded by the National Institutes of Health have discovered a potential strategy for developing treatments to stem the disease process in Alzheimer's disease. It's based on unclogging removal of toxic debris that accumulates in patients' brains, by blocking activity of a little-known regulator protein called CD33. http://medicalxpress.com/news/2013-04-alzheimer-gene-potential-treatment.html Alzheimer's disease & dementia Thu, 25 Apr 2013 12:00:12 EST news286108610 Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in the inflammatory response in the brain is a crucial mechanism driving Late Onset Alzheimer's Disease (LOAD). The findings, published online today in the journal Cell, provide new understanding of key pathways and genes involved in LOAD and valuable insights to develop potential therapies for the disease. http://medicalxpress.com/news/2013-04-key-mechanism-common-alzheimer-disease.html Alzheimer's disease & dementia Thu, 25 Apr 2013 12:00:04 EST news286108563 The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important parts of the nerve cell that are involved in the cell's energy metabolism operate in the early stages of the disease. These somewhat surprising results shed new light on how neuronal metabolism relates to the development of the disease. http://medicalxpress.com/news/2013-04-early-stage-alzheimer-disease.html Alzheimer's disease & dementia Mon, 22 Apr 2013 15:00:13 EST news285854606 Evidence indicates that the accumulation of amyloid-beta proteins, which form the plaques found in the brains of Alzheimer's patients, is critical for the development of Alzheimer's disease, which impacts 5.4 million Americans. And not just the quantity, but also the quality of amyloid-beta peptides is crucial for Alzheimer's initiation. The disease is triggered by an imbalance in two different amyloid species—in Alzheimer's patients, there is a reduction in a relative level of healthy amyloid-beta 40 compared to 42. http://medicalxpress.com/news/2013-04-brain-alzheimer-disease.html Alzheimer's disease & dementia Thu, 18 Apr 2013 11:50:27 EST news285504615 Close family members of people with Alzheimer's disease are more than twice as likely as those without a family history to develop silent buildup of brain plaques associated with Alzheimer's disease, according to researchers at Duke Medicine. http://medicalxpress.com/news/2013-04-family-history-alzheimer-abnormal-brain.html Alzheimer's disease & dementia Wed, 17 Apr 2013 17:00:01 EST news285423778 (Medical Xpress)—A new study from researchers at the University of Florida may have uncovered a critical factor that drives the relentless progression of Alzheimer's disease ― a discovery that could eventually slow its progression. http://medicalxpress.com/news/2013-04-uncovers-key-factor-alzheimer.html Alzheimer's disease & dementia Tue, 16 Apr 2013 06:10:01 EST news285310460 (HealthDay)—Regular exercise slows disability and prevents falls in patients with Alzheimer's disease without increasing overall costs, a new study from Finland says. http://medicalxpress.com/news/2013-04-people-alzheimer-nursing-homes.html Alzheimer's disease & dementia Mon, 15 Apr 2013 16:17:11 EST news285261424 A new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer's disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the disease, according to a study, published in the Journal of Neuroscience. The study was supported by the National Institutes of Health. http://medicalxpress.com/news/2013-04-next-generation-alzheimer-disease.html Alzheimer's disease & dementia Tue, 09 Apr 2013 17:00:07 EST news284745162 Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops. http://medicalxpress.com/news/2013-04-genetic-markers-id-alzheimer-pathway.html Alzheimer's disease & dementia Thu, 04 Apr 2013 12:32:42 EST news284297477 Amyloids—clumps of misfolded proteins found in the brains of people with Alzheimer's disease and other neurodegenerative disorders—are the quintessential bad boys of neurobiology. They're thought to muck up the seamless workings of the neurons responsible for memory and movement, and researchers around the world have devoted themselves to devising ways of blocking their production or accumulation in humans. http://medicalxpress.com/news/2013-04-accused-complicity-alzheimer-amyloid-proteins.html Alzheimer's disease & dementia Wed, 03 Apr 2013 14:00:07 EST news284215646 (Medical Xpress)—An Australian study has shown that plaque, long considered to be the hallmark of Alzheimer's disease, is one of the last events to occur in the Alzheimer's brain. This finding will impact the current debate about how best to diagnose and treat Alzheimer's disease. http://medicalxpress.com/news/2013-04-plaque-alzheimer-disease.html Alzheimer's disease & dementia Wed, 03 Apr 2013 10:50:02 EST news284204220 The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger pangs, and related hormonal pathways, may be as important to the much-discussed value of "caloric restriction" as actually eating less. http://medicalxpress.com/news/2013-04-hungry-brain-alzheimer-disease.html Alzheimer's disease & dementia Wed, 03 Apr 2013 09:27:10 EST news284200011 (HealthDay)—Researchers are testing whether applying electrical stimulation directly to the brains of people with Alzheimer's disease might improve thinking, focus and alertness. http://medicalxpress.com/news/2013-03-implanted-brain-alzheimer.html Alzheimer's disease & dementia Thu, 28 Mar 2013 13:59:57 EST news283697990 Scientists at the Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process. The team further found that disruptions to this process occur in mouse models of Alzheimer's disease—and identified two therapeutic strategies that reduce these disruptions. http://medicalxpress.com/news/2013-03-scientists-dna-brain.html Alzheimer's disease & dementia Sun, 24 Mar 2013 14:10:01 EST news283335265 (HealthDay)—There's more troubling news for America's aging population: A new report finds that one in every three seniors now dies while suffering from Alzheimer's or another form of dementia. http://medicalxpress.com/news/2013-03-seniors-die-dementia.html Alzheimer's disease & dementia Tue, 19 Mar 2013 12:26:20 EST news282914770 A study in the JAMA Neurology (formerly the Archives of Neurology) suggests that controlling or preventing risk factors such as hypertension earlier in life may limit or delay the brain changes associated with Alzheimer's disease and other age-related neurological deterioration. http://medicalxpress.com/news/2013-03-uncontrolled-hypertension-alzheimer-disease.html Alzheimer's disease & dementia Mon, 18 Mar 2013 18:36:24 EST news282850567 An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found. http://medicalxpress.com/news/2013-03-prion-protein-iron-metabolism.html Alzheimer's disease & dementia Wed, 13 Mar 2013 12:46:49 EST news282397602 Technology capable of diagnosing Alzheimer's disease long before its symptoms appear won a coveted honor for innovation at the South by Southwest (SXSW) festival. http://medicalxpress.com/news/2013-03-technology-alzheimer-sxsw-prize.html Alzheimer's disease & dementia Wed, 13 Mar 2013 05:28:44 EST news282371300 Sleep is disrupted in people who likely have early Alzheimer's disease but do not yet have the memory loss or other cognitive problems characteristic of full-blown disease, researchers at Washington University School of Medicine in St. Louis report March 11 in JAMA Neurology. http://medicalxpress.com/news/2013-03-loss-alzheimer-symptoms.html Alzheimer's disease & dementia Mon, 11 Mar 2013 16:00:03 EST news282221783 (Medical Xpress)—Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer's disease. Hyperammonemia is a life-threatening condition that can affect patients at any age. It is caused by abnormal, high levels of ammonia in the blood. http://medicalxpress.com/news/2013-03-scientists-buphenyl-drug-alzheimer-disease.html Alzheimer's disease & dementia Mon, 11 Mar 2013 09:50:33 EST news282214226 According to a 2012 World Health Organization report, over 35 million people worldwide currently have dementia, a number that is expected to double by 2030 (66 million) and triple by 2050 (115 million). Alzheimer's disease, the most common form of dementia, has no cure and there are currently only a handful of approved treatments that slow, but do not prevent, the progression of symptoms. http://medicalxpress.com/news/2013-03-worming-treatments-alzheimer-disease.html Alzheimer's disease & dementia Thu, 07 Mar 2013 11:02:51 EST news281876562 (Medical Xpress)—University of British Columbia researchers have successfully normalized the production of blood vessels in the brain of mice with Alzheimer's disease (AD) by immunizing them with amyloid beta, a protein widely associated with the disease. http://medicalxpress.com/news/2013-03-drugs-blood-vessels-candidates-alzheimer.html Alzheimer's disease & dementia Thu, 07 Mar 2013 07:09:59 EST news281862590