http://medicalxpress.com/cancer-news/ en-us Medical Xpress provides the latest news on cancer, health, medicines, cancer treatments, cancer research, cancer studies and types of cancer. (Medical Xpress)—A new study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. The findings may reveal a novel chemotherapeutic approach to prevent the spread of cancers. http://medicalxpress.com/news/2013-06-paper-insights-cancer-cells-cell.html Cancer Wed, 19 Jun 2013 06:30:42 EST news290842234 Recent research has shown that cancer cells have a much different – and more complex – metabolism than normal cells. Now, scientists at The University of Texas at Dallas have found that exploiting these differences might provide a new strategy to combat lung cancer. http://medicalxpress.com/news/2013-06-approach-lung-cancer.html Cancer Tue, 18 Jun 2013 16:48:41 EST news290792913 Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point. http://medicalxpress.com/news/2013-06-scientists-egfr-crucial-message-cancer-promoting.html Cancer Tue, 18 Jun 2013 16:20:19 EST news290791210 (Medical Xpress)—When people think about genes and their relationship to cancer, most probably think about a person's hereditary cancer risk, especially after Angelina Jolie's recent news about her inherited breast and ovarian cancer risk associated with the BRCA1 and BRCA2 gene abnormalities. But genetic counselors will tell you that only about 5 to 10 percent of cancers are caused by inherited genetic mutations. http://medicalxpress.com/news/2013-06-link-genes-cancer.html Cancer Tue, 18 Jun 2013 06:40:02 EST news290755406 Harvard Stem Cell Institute (HSCI) researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity. http://medicalxpress.com/news/2013-06-undruggable-druggable-cancer-drug.html Cancer Mon, 17 Jun 2013 17:53:23 EST news290710394 Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils. http://medicalxpress.com/news/2013-06-scientists-biomarker-hpv-related-oropharynx-cancer.html Cancer Mon, 17 Jun 2013 17:41:42 EST news290709694 (Medical Xpress)—Yale researchers eradicated most melanoma tumors by exposing them to a fast-acting virus, they report in the June 15 edition of the Journal of Virology. http://medicalxpress.com/news/2013-06-fast-acting-virus-melanoma-mice.html Cancer Mon, 17 Jun 2013 07:46:28 EST news290673978 A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study. http://medicalxpress.com/news/2013-06-osteoporosis-drug-growth-breast-cancer.html Cancer Sat, 15 Jun 2013 14:00:01 EST news290443863 Here's a good reason to pay attention in math class. Nature Communications has published a paper from Ottawa researchers today, outlining how advanced mathematical modelling can be used in the fight against cancer. The technique predicts how different treatments and genetic modifications might allow cancer-killing, oncolytic viruses to overcome the natural defences that cancer cells use to stave off viral infection. http://medicalxpress.com/news/2013-06-math-cancer-cells.html Cancer Fri, 14 Jun 2013 11:33:44 EST news290361512 (Medical Xpress)—Basal cell carcinoma is the most common form of cancer. While unlikely to metastasize and therefore associated with low mortality, it can be disfiguring and costly to treat. Typically, it has been seen on the heads of elderly outdoor enthusiasts: think dockworkers, golfers or Sun Belt retirees with blotchy, scabbed facial skin. http://medicalxpress.com/news/2013-06-reveals-indoor-tanning-skin-cancer.html Cancer Fri, 14 Jun 2013 06:58:09 EST news290411873 A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the journal Cancer Research. http://medicalxpress.com/news/2013-06-developmental-protein-role-cancer.html Cancer Fri, 14 Jun 2013 00:10:01 EST news290361470 (Medical Xpress)—A study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) has identified an abnormal metabolic pathway that drives cancer-cell growth in a particular glioblastoma subtype. The finding might lead to new therapies for a subset of patients with glioblastoma, the most common and lethal form of brain cancer. http://medicalxpress.com/news/2013-06-metabolic-molecule-growth-aggressive-brain.html Cancer Thu, 13 Jun 2013 16:40:42 EST news290360432 According to new research from the Monell Center and collaborating institutions, odors from human skin cells can be used to identify melanoma, the deadliest form of skin cancer. In addition to detecting a unique odor signature associated with melanoma cells, the researchers also demonstrated that a nanotechnology-based sensor could reliably differentiate melanoma cells from normal skin cells. The findings suggest that non-invasive odor analysis may be a valuable technique in the detection and early diagnosis of human melanoma. http://medicalxpress.com/news/2013-06-scent-melanoma-early-non-invasive-diagnosis.html Cancer Thu, 13 Jun 2013 14:51:34 EST news290353579 According to the American Cancer Society, nearly 40,000 women in the United States will succumb to breast cancer this year. Most of these women will die not from the primary tumor but rather tumor recurrence – the reappearance of the disease following treatment. http://medicalxpress.com/news/2013-06-protein-breast-cancer-recurrence-animal.html Cancer Thu, 13 Jun 2013 12:00:01 EST news290343094 Genetic variations, known as single nucleotide polymorphisms (SNPs), in or near the genes ZNF423 and CTSO were associated with breast cancer risk among women who underwent prevention therapy with tamoxifen and raloxifene, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2013-06-newly-markers-breast-cancer-therapy.html Cancer Thu, 13 Jun 2013 10:52:34 EST news290339547 Researchers in Germany have found a new way to exploit the differences between cancer cells and normal cells that could lead to new treatments. http://medicalxpress.com/news/2013-06-exploit-cancer-faulty-defence-mechanism.html Cancer Thu, 13 Jun 2013 07:32:15 EST news290327522 (Medical Xpress)—UK and Australian scientists have been able to show ways in which we can markedly improve drug targeting of solid tumours, using tiny 'biosensors' along with new advanced imaging techniques. http://medicalxpress.com/news/2013-06-nanotechnology-track-drug-action-pancreatic.html Cancer Wed, 12 Jun 2013 04:47:27 EST news290231228 Scientists at The Scripps Research Institute (TSRI) have identified key triggers of an important cancer-blocking mechanism in cells. http://medicalxpress.com/news/2013-06-scientists-uncover-natural-anticancer-mechanism.html Cancer Tue, 11 Jun 2013 15:56:56 EST news290185009 Progesterone, a female hormone that can be used as a therapy for endometrial cancer, eliminates tumor cells indirectly by binding to its receptor in stromal or connective tissue cells residing in the tumor microenvironment, according to a study from the G.O. Discovery Lab team and collaborators at UCLA. http://medicalxpress.com/news/2013-06-hormonal-treatment-endometrial-cancer-malignant.html Cancer Tue, 11 Jun 2013 09:14:53 EST news290160885 Men with prostate cancer may significantly improve their survival chances with a simple change in their diet, a new study led by UC San Francisco has found. http://medicalxpress.com/news/2013-06-men-prostate-cancer-healthy-vegetable.html Cancer Mon, 10 Jun 2013 16:00:04 EST news290095555 (Medical Xpress)—Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia (ALL), according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation. http://medicalxpress.com/news/2013-06-epigenetic-factor-key-role-fueling.html Cancer Mon, 10 Jun 2013 13:33:41 EST news290090014 In the process of metastasis, the movement of cancer cells to different parts of the body, a specific master regulator gene plays a central role: a transcription factor named Sox4 activates a sequence of genes and triggers the formidable process. This finding is reported by researchers from the University of Basel and from the Friedrich Miescher Institute in Cancer Cell. Inhibition of Sox4 and subsequent processes may prevent metastasis in cancer patients. http://medicalxpress.com/news/2013-06-master-cancer-metastasis.html Cancer Mon, 10 Jun 2013 12:00:02 EST news290079711 (Medical Xpress)—Training our immune systems to fight cancer is an appealing prospect. Why wouldn't we want to launch our own internal army against one of our most-hated foes? But the process is a bit like learning to spot a single traitor in a stadium full of innocent bystanders. After all, at the most basic level, cancer cells are simply our own tissue making bad choices about how to grow and spread. http://medicalxpress.com/news/2013-06-clinical-trial-scientists-immune-cancer.html Cancer Mon, 10 Jun 2013 07:12:31 EST news290066948 (Medical Xpress)—Scientists have discovered genes that control shape changes in melanoma skin cancer cells, allowing them to wriggle free and spread around the body, according to new research published in Nature Cell Biology. http://medicalxpress.com/news/2013-06-shape-shifting-cells-skin-cancer.html Cancer Mon, 10 Jun 2013 06:50:25 EST news290065818 Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2013-06-clinical-sequencing-technology-diverse-cancers.html Cancer Fri, 07 Jun 2013 15:28:55 EST news289837728 Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013. Dartmouth researchers are trying to understand the key pathways that distinguish how a normal blood cell grows and divides compared to the altered growth that occurs in leukemia. In addition to the treatment of leukemia, the work has relevance for expanding umbilical cord blood or bone marrow stem cells for transplantation. http://medicalxpress.com/news/2013-06-molecular-pathway-affected-poor-prognosis-childhood.html Cancer Thu, 06 Jun 2013 17:03:05 EST news289756946 Cancer cells' appetite for sugar may have serious consequences for immune cell function, researchers at Washington University School of Medicine in St. Louis have learned. http://medicalxpress.com/news/2013-06-tumors-disable-immune-cells-sugar.html Cancer Thu, 06 Jun 2013 12:00:08 EST news289724488 As tumors grow, their centers are squeezed of oxygen. And so tumors must flip specific genetic switches to survive in these hypoxic environments. A series of studies funded to do only basic science and published today in the journal Cell reports the serendipitous discovery of a druggable target necessary for the survival of tumors in these low-oxygen environments. http://medicalxpress.com/news/2013-06-protein-linked-tumor-growth-potential.html Cancer Thu, 06 Jun 2013 12:00:07 EST news289724194 A combination of nontoxic dietary and hyperbaric oxygen therapies effectively increased survival time in a mouse model of aggressive metastatic cancer, a research team from the Hyperbaric Biomedical Research Laboratory at the University of South Florida has found. http://medicalxpress.com/news/2013-06-nontoxic-cancer-therapy-effective-metastatic.html Cancer Wed, 05 Jun 2013 17:00:02 EST news289669447 (Medical Xpress)—A recent article in the New England Journal of Medicine describes genetic testing of a rare blood cancer called atypical chronic neutrophilic leukemia (CNL) that revealed a new mutation present in most patients with the disease. The mutation also serves as an Achilles heel, allowing doctors at the University of Colorado Cancer Center to prescribe a never-before-used, targeted treatment. The first patient treated describes his best snowboarding season ever. http://medicalxpress.com/news/2013-06-disease-to-drug-genetic-snowboarder-slopes.html Cancer Wed, 05 Jun 2013 14:43:15 EST news289662188