http://medicalxpress.com/inflammatory-disorders-news/ en-us Medical Xpress provides the latest research news on inflammatory disorders The negative effects of poorly controlled asthma symptoms on sleep quality and academic performance in urban schoolchildren has been confirmed in a new study. http://medicalxpress.com/news/2013-05-asthma-symptoms-impair-quality-school.html Inflammatory disorders Tue, 21 May 2013 09:24:13 EST news288347043 Patients with inflammatory bowel disease (IBD) are at higher risk of melanoma, a form of skin cancer, report researchers at Mayo Clinic. Researchers found that IBD is associated with a 37 percent greater risk for the disease. The findings were presented at the Digestive Disease Week 2013 conference in Orlando, Fla. http://medicalxpress.com/news/2013-05-inflammatory-bowel-disease-melanoma.html Inflammatory disorders Mon, 20 May 2013 09:07:34 EST news288259645 (Medical Xpress)—Inflammation is an important response in the body - it helps you to kill off invaders such bacteria that could cause a harmful infection. But if it's chronic or uncontrolled, inflammation can also cause trouble in conditions including rheumatoid arthritis, inflammatory bowel disease and a potentially fatal immune reaction to infection called sepsis. http://medicalxpress.com/news/2013-05-inflammation.html Inflammatory disorders Tue, 14 May 2013 09:48:06 EST news287743679 New research by medical students working in the Breathe Well Centre of Research Excellence at the UTAS School of Medicine has revealed swimming has health benefits for young people with asthma, with no adverse effects on asthma control or exacerbations. http://medicalxpress.com/news/2013-05-reveals-beneficial-young-people-asthma.html Inflammatory disorders Fri, 10 May 2013 09:30:01 EST news287394678 An estimated 4,837,000 asthmatics with allergic bronchopulmonary aspergillosis (ABPA) could benefit substantially from antifungal treatment, say researchers from The University of Manchester and the University of Toronto. http://medicalxpress.com/news/2013-05-million-asthmatics-benefit-antifungal-therapy.html Inflammatory disorders Wed, 08 May 2013 08:06:33 EST news287219035 Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks an inflammatory process that fuels the buildup of artery-clogging plaque. The findings, made in mice and confirmed with human data, suggest new therapeutic targets for reducing heart disease in people with type 1 diabetes. Led by Columbia University Medical Center (CUMC) researchers in collaboration with investigators at New York University and the University of Pittsburgh, the study was published today in the online edition of Cell Metabolism. http://medicalxpress.com/news/2013-05-diabetes-heart-disease-linked-inflammatory.html Inflammatory disorders Tue, 07 May 2013 12:00:01 EST news287139513 University of Adelaide researchers at the Royal Adelaide Hospital are involved in the world's biggest study of its kind investigating a possible new treatment for asthma. http://medicalxpress.com/news/2013-05-trial-asthma-drug-lung-inflammation.html Inflammatory disorders Wed, 01 May 2013 08:40:01 EST news286615379 Patients with rheumatoid arthritis (RA) who initiated use of anti-tumor necrosis factor therapies were not at a higher risk of developing herpes zoster (shingles), compared with patients who initiated nonbiologic treatment regimens, according to research from the University of Alabama at Birmingham (UAB) and the Oregon Health and Science University. The findings appeared in the March 6, 2013, issue of the Journal of the American Medical Association (JAMA). http://medicalxpress.com/news/2013-04-biologic-therapies-inflammatory-diseases-shingles.html Inflammatory disorders Fri, 19 Apr 2013 09:40:06 EST news285581362 A Johns Hopkins Children's Center survey of 102 clinicians who treat teenage girls with pelvic inflammatory disease (PID) has found that official guidelines designed to inform decisions about hospitalization versus outpatient care leave some clinicians scratching their heads. http://medicalxpress.com/news/2013-04-federal-guidelines-teen-pid-clarification.html Inflammatory disorders Tue, 09 Apr 2013 16:49:28 EST news284744962 A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues. http://medicalxpress.com/news/2013-04-key-pathway-dangerous-out-of-control-inflammation.html Inflammatory disorders Tue, 09 Apr 2013 16:47:06 EST news284744805 In a recently published collaborative study by the University of Otago, Wellington, the University of California, Berkeley, and Stanford University it has been shown that there are no ill effects from low level hydrogen sulphide gas on asthma symptoms or diagnosis in Rotorua. Hydrogen sulphide or H2S is responsible for the characteristic "sulphur" smell of Rotorua. http://medicalxpress.com/news/2013-04-rotorua-hydrogen-sulphide-worsen-asthma.html Inflammatory disorders Wed, 03 Apr 2013 08:21:44 EST news284195949 Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease. This enzyme is produced by white blood cells called neutrophils, which play an important role in the body's immune defense against bacteria. The researchers found that obese humans and mice have increased neutrophil elastase activity and decreased levels of α1-antitrypsin, a protein that inhibits the elastase. When the team reversed this imbalance in a mouse model and fed them a high-fat diet, the mice were resistant to body weight gain, insulin resistance (a precursor to type 2 diabetes), and fatty liver disease. http://medicalxpress.com/news/2013-04-white-blood-cell-enzyme-contributes.html Inflammatory disorders Tue, 02 Apr 2013 16:16:32 EST news284138185 (Medical Xpress)—New research by Yale University scientists sets the stage for improved management of acute tissue inflammation related to wounds and chronic inflammatory diseases by advancing current understanding of inflammatory processes. http://medicalxpress.com/news/2013-03-inflammation-white-blood-cell-key.html Inflammatory disorders Thu, 28 Mar 2013 07:30:02 EST news283674268 Inflammation is the body's normal response to injury. While it may be a natural defense system, it can lead to disease development if it becomes chronic. A University of Alabama at Birmingham (UAB) expert says one way to fight inflammation is with food. http://medicalxpress.com/news/2013-03-foods-inflammation.html Inflammatory disorders Tue, 26 Mar 2013 08:30:05 EST news283505397 New research conducted in 10 European cities has estimated that 14% of chronic childhood asthma is due to exposure to traffic pollution near busy roads. http://medicalxpress.com/news/2013-03-road-traffic-pollution-passive-childhood.html Inflammatory disorders Thu, 21 Mar 2013 20:00:01 EST news283105325 New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms. The study, published in the Proceedings of the National Academies of Sciences, indicates the importance of continuing to explore B cells as a therapeutic target to treat these diseases. Barbara Nikolajczyk, PhD, associate professor of microbiology at BUSM, is the study's senior author. http://medicalxpress.com/news/2013-03-reveals-therapeutic-inflammation-diabetes.html Inflammatory disorders Tue, 12 Mar 2013 13:19:29 EST news282313161 Although patients with rheumatoid arthritis (RA) have a disproportionately higher incidence of herpes zoster (shingles), an analysis that included nearly 60,000 patients with RA and other inflammatory diseases found that those who initiated anti-tumor necrosis factor therapies were not at higher risk of herpes zoster compared with patients who initiated nonbiologic treatment regimens, according to a study appearing in the March 6 issue of JAMA. http://medicalxpress.com/news/2013-03-therapies-inflammatory-diseases-shingles.html Inflammatory disorders Tue, 05 Mar 2013 16:00:02 EST news281710245 Scientists from Brigham and Women's Hospital are on the brink of the next treatment advancement that may spell relief for the nearly nineteen million adults and seven million children in the United States suffering from asthma. The scientists discovered two new drug targets in the inflammatory response pathway responsible for asthma attacks. http://medicalxpress.com/news/2013-02-scientists-molecule-duty-asthma.html Inflammatory disorders Wed, 27 Feb 2013 14:00:05 EST news281190194 (Medical Xpress)—Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not understood the mechanisms that underlie it. http://medicalxpress.com/news/2013-02-scientists-underlying-mechanisms-chronic-inflammation-associated.html Inflammatory disorders Sat, 23 Feb 2013 06:56:08 EST news280824946 Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition. http://medicalxpress.com/news/2013-02-mouse-inflammatory-genomic-response-injuries.html Inflammatory disorders Mon, 11 Feb 2013 15:00:01 EST news279804831 (Medical Xpress)—Scientists have long puzzled over why "bad" bacteria such as E. coli can thrive in the guts of those with inflammatory bowel disease (IBD), causing serious diarrhea. Now UC Davis researchers have discovered the answer—one that may be the first step toward finding new and better treatments for IBD. http://medicalxpress.com/news/2013-02-scientists-key-growth-bad-bacteria.html Inflammatory disorders Thu, 07 Feb 2013 15:56:09 EST news279474958 Leading international researchers and doctors are meeting at the University of Otago, Wellington this week to identify new approaches to reducing the very high levels of rheumatic fever in New Zealand and Australia. http://medicalxpress.com/news/2013-02-approaches-combating-rheumatic-fever-children.html Inflammatory disorders Tue, 05 Feb 2013 06:20:01 EST news279267041 (Medical Xpress)—Scientists trying to create drugs to treat chronic inflammation in diseases like arthritis now have a new culprit known MMP2. New University of British Columbia research shows that this enzyme works as a master switch to activate inflammatory diseases. http://medicalxpress.com/news/2013-01-master-discovery-road-treatment-arthritis.html Inflammatory disorders Wed, 23 Jan 2013 07:10:02 EST news278145932 University of New South Wales researchers have developed a compound that has had a surprise result: being effective in the prevention of asthma. http://medicalxpress.com/news/2013-01-reversing-symptoms-asthma.html Inflammatory disorders Tue, 22 Jan 2013 06:28:47 EST news278058507 Asthma is a serious condition that affects more than 25.7 million Americans, and is responsible for nearly 4,000 deaths annually. While the cause of asthma remains unknown, a study released today in the January issue of Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), has concluded that low birth weight is not associated with asthma risk in young children. http://medicalxpress.com/news/2013-01-birth-weight-asthma.html Inflammatory disorders Tue, 15 Jan 2013 00:00:01 EST news277383567 Children who frequently eat fast food are far likelier to have severe asthma compared to counterparts who tuck into fruit, a large international study published on Monday said. http://medicalxpress.com/news/2013-01-fast-food-linked-child-asthma.html Inflammatory disorders Mon, 14 Jan 2013 09:46:19 EST news277379172 (Medical Xpress)—Testing asthmatic children for a specific gene could prevent their condition worsening, according to new research by scientists in Dundee and Brighton. http://medicalxpress.com/news/2013-01-gene-asthmatic-children-treatment.html Inflammatory disorders Tue, 08 Jan 2013 08:33:40 EST news276856410 A woman's exposure to high pollen levels in late pregnancy increases the risk of early asthma in the child, according to a group of researchers at Sweden's Umeå University in a recent study. http://medicalxpress.com/news/2013-01-pollen-exposure-pregnancy-affects-child.html Inflammatory disorders Mon, 07 Jan 2013 08:57:33 EST news276771433 Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, including inflammatory bowel disease and colorectal cancer; however, it is unclear if dysbiosis can instigate disease or if it is a consequence of the underlying disorder. http://medicalxpress.com/news/2013-01-bacterial-imbalance-contributes-intestinal-inflammation.html Inflammatory disorders Wed, 02 Jan 2013 12:00:09 EST news276347346 (Medical Xpress)—Many illnesses, including psoriasis, include inflammatory responses that occur without an apparent infection and worsen with stress. In a study using cultured human mast cells in vitro and in rats, researchers from Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts University identified mitochondrial particles—secreted from live, activated mast cells—as a possible trigger of the inflammation that is common in such illnesses. http://medicalxpress.com/news/2013-01-mitochondrial-components-trigger-auto-inflammatory-illnesses.html Inflammatory disorders Wed, 02 Jan 2013 09:01:05 EST news276339657