http://medicalxpress.com/ en-us Medical Xpress provides the latest news from Baylor College of Medicine In some neurodegenerative diseases, and specifically in a devastating inherited condition called spinocerebellar ataxia 1 (SCA1), the answer may not be an "all-or-nothing," said a collaboration of researchers from Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and the University of Minnesota in a report that appears online in the journal Nature. The problem might be solved with just a little less. http://medicalxpress.com/news/2013-05-protein-neurodegenerative-disorders.html Neuroscience Wed, 29 May 2013 13:00:13 EST news289050464 In a paper published in Science Express, a group of experts led by bioethicists in the Center for Medical Ethics and Health Policy at Baylor College of Medicine provide a framework for the new American College of Medical Genetics and Genomics (ACMG) recommendations on reporting incidental findings in clinical exome and genome sequencing. http://medicalxpress.com/news/2013-05-ethicists-framework-incidental-gene-sequencing.html Genetics Thu, 16 May 2013 14:00:01 EST news287931187 Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor College of Medicine in a report that appears online in the journal Science Translational Medicine. http://medicalxpress.com/news/2013-04-signature-circulating-breast-tumor-cells.html Cancer Wed, 10 Apr 2013 14:00:02 EST news284818141 Is the era of targeted therapy for breast cancer at hand? It could be, said experts at the Lester and Sue Smith Breast Center at Baylor College of Medicine – at least for a certain population of women. http://medicalxpress.com/news/2013-04-breast-cancer-patients-benefit-combined.html Cancer Mon, 08 Apr 2013 16:00:01 EST news284644677 Mutations in a protein called SPOP (speckle-type POZ protein) disarm it, allowing another protein called steroid receptor coactivator-3 (SRC-3) to encourage the proliferation and spread of prostate cancer cells, said researchers led by those at Baylor College of Medicine in a report that appears online in Proceedings of the National Academy of Sciences. http://medicalxpress.com/news/2013-04-loss-tumor-suppressor-spop-cancer.html Cancer Mon, 01 Apr 2013 15:00:15 EST news284032822 Few things in life are inevitable – death, taxes, and, if you live long enough, osteoarthritis. No treatment will stop or significantly slow the disease, and joint replacement is the only definitive treatment. That may change, however, as researchers such as Dr. Brendan Lee, professor of molecular and human genetics at Baylor College of Medicine, and his colleagues unravel the effects of a naturally occurring protein called lubricin or Proteoglycans 4 that appears to protect against the age as well as post-injury related changes. A report on their research appears online in the journal Science Translational Medicine. http://medicalxpress.com/news/2013-03-protein-inevitability-osteoarthritis.html Arthritis & Rheumatism Wed, 13 Mar 2013 14:00:19 EST news282393617 (Medical Xpress)—Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your brain has taken a short-term memory – the introduction – and converted it into a long-term one. The molecular key to this activity is mTORC2 (mammalian target of rapamycin complex 2), according to researchers at Baylor College of Medicine in an article that appeared online in the journal Nature Neuroscience. http://medicalxpress.com/news/2013-03-storage-mechanism-memory.html Neuroscience Tue, 05 Mar 2013 12:14:56 EST news281708089 The three most important factors in real estate are location, location, location, and the same might be said for mutations in the gene MECP2, said researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital in a report in the journal Cell. http://medicalxpress.com/news/2013-02-mutation-key-prognosis.html Genetics Thu, 28 Feb 2013 12:32:15 EST news281277127 Bone marrow cells that produce brain-derived eurotrophic factor (BDNF), known to affect regulation of food intake, travel to part of the hypothalamus in the brain where they "fine-tune" appetite, said researchers from Baylor College of Medicine and Shiga University of Medical Science in Otsu, Shiga, Japan, in a report that appears online in the journal Nature Communications. http://medicalxpress.com/news/2013-02-blood.html Medical research Tue, 26 Feb 2013 11:00:11 EST news281091463 As patients and physicians share decision-making in choices among treatment options, decision aids such as videos, websites, pamphlets or books are coming to play an important role. However, in some cases, it may be ethical for the decision aids to provide a "nudge" toward a particular option, said researchers from Baylor College of Medicine, the Michael E. DeBakey Veterans Affairs Medical Center and the University of Texas MD Anderson Cancer Center in a report that appears in the journal Health Affairs. http://medicalxpress.com/news/2013-02-nudge-ethical-choice.html Health Mon, 04 Feb 2013 16:00:06 EST news279197873 In a study of patients at two HIV clinics in the Houston area, researchers at Baylor College of Medicine and the Michael E. DeBakey Veterans Affairs Medical Center found that those who were satisfied with the care they received had higher adherence to care and higher retention rates. Their report appears today in PLOS ONE. http://medicalxpress.com/news/2013-01-patient-satisfaction-hiv.html HIV & AIDS Wed, 30 Jan 2013 17:13:42 EST news278788362 Deleting or reducing expression of a gene that carries the code for tau, a protein associated with Alzheimer's disease, can prevent seizures in a severe type of epilepsy linked to sudden death, said researchers at Baylor College of Medicine and the Mayo Clinic in Jacksonville, Fla., in a report in the current issue of the Journal of Neuroscience. http://medicalxpress.com/news/2013-01-tau-seizures-sudden-death-severe.html Neuroscience Tue, 22 Jan 2013 17:00:01 EST news278090923 It looks like your mother was on to something when she said, "Eat your vegetables!" A concentrated form of a compound called sulforaphane found in broccoli and other cruciferous vegetables has been shown to reduce the number of acute lymphoblastic leukemia cells in the lab setting, said researchers at Baylor College of Medicine. The findings appear in the current edition of PLOS ONE. http://medicalxpress.com/news/2012-12-vegetable-compound-ingredient-leukemia.html Cancer Wed, 12 Dec 2012 17:00:44 EST news274554022 In 1999, Dr. Huda Zoghbi and colleagues at Baylor College of Medicine identified the genetic cause of Rett syndrome (a neurological disorder that begins after birth) – MECP2 mutation. Too little of the MeCP2 protein associated with the gene causes the girls whom it affects to regress, gradually losing their speech, the use of their hands and many cognitive functions. http://medicalxpress.com/news/2012-12-mecp2-duplication-affects-immune-brain.html Medical research Wed, 05 Dec 2012 14:00:02 EST news273926510 The ability of the eye of a fruit fly (Drosophila melanogaster) to respond to light depends on a delicate ballet that keeps the supply of light sensors called rhodopsin constant as photoreceptors turn on and off in response to light exposures, said researchers from Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital in an article that appears online in the journal PLOS Biology. http://medicalxpress.com/news/2012-12-crag-fantastic-photoreceptors.html Neuroscience Tue, 04 Dec 2012 17:06:39 EST news273863189