http://medicalxpress.com/ en-us Medical Xpress provides the latest news from Institute for Research in Biomedicine (IRB Barcelona) ICREA professor Raúl Méndez publishes a study in Nature describing how the CPBE1 protein "takes the brakes off" the production of proteins associated with the cell switch from being healthy to tumorous. The study highlights CPEB proteins as promising targets, thus opening up a new and unexplored therapeutic window. The lab has developed a system for screening compounds that impede the action of CPEB proteins in tumors. http://medicalxpress.com/news/2013-02-team-mechanism-tumor.html Cancer Sun, 24 Feb 2013 13:00:39 EST news280918992 Scientists at IRB Barcelona present a model to demonstrate the correlation between genomic instability and cancer. http://medicalxpress.com/news/2012-11-cell-cancerous.html Cancer Thu, 29 Nov 2012 09:13:22 EST news273402793 A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability of colon cancer to metastasize lies in the healthy cells, called stroma, that surround the tumour. Although the stroma has long been hypothesized to be complicit in this process, this study marks the first time that healthy cells in the microenvironment have been observed to play a fundamental role in allowing metastasis to occur in a specific tumour type. http://medicalxpress.com/news/2012-11-scientists-key-colon-cancer-metastasize.html Cancer Mon, 12 Nov 2012 12:00:01 EST news271942785 (Phys.org)—Researchers headed by Maria Macias an ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona) and Joan Massagué, a Howard Hughes Medical Institute investigator at Memorial Sloan-Kettering Cancer Center (MSKCC) in New York, have identified a new molecular mechanism that plays a crucial role in the control of the activation of certain genes associated with cancer. http://medicalxpress.com/news/2012-08-molecular-interactions-inhibition-tgf-beta-signaling.html Medical research Fri, 24 Aug 2012 10:18:09 EST news265022275 A study by Travis H. Stracker, researcher at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with scientists at the Memorial Sloan Kettering Cancer Center (MSKCC) in New York, reveals new information about the origin of tumors. http://medicalxpress.com/news/2012-06-uncover-clues-cancer.html Cancer Wed, 06 Jun 2012 10:41:35 EST news258198088 A team headed by Eduardo Soriano at the Institute for Research in Biomedicine (IRB Barcelona) has published a study in Nature Communications describing a new family of six genes whose function regulates the movement and position of mitochondria in neurons. Many neurological conditions, including Parkinson's and various types of Charcot-Marie-Tooth disease, are caused by alterations of genes that control mitochondrial transport, a process that provides the energy required for cell function. http://medicalxpress.com/news/2012-05-discovery-family-key-mitochondrial-proteins.html Medical research Wed, 09 May 2012 11:21:08 EST news255781179