http://medicalxpress.com/ en-us Medical Xpress provides the latest news from Lawrence Berkeley National Laboratory (Medical Xpress)—For decades, no one worried much about the air quality inside people's homes unless there was secondhand smoke or radon present. Then scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) made the discovery that the aggregate health consequences of poor indoor air quality are as significant as those from all traffic accidents or infectious diseases in the United States. One major source of indoor pollutants in the home is cooking. http://medicalxpress.com/news/2013-04-hidden-dangers-air.html Health Thu, 11 Apr 2013 08:10:01 EST news284885427 (Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet? It turns out that running longer distances actually decreases a person's risk of osteoarthritis and hip replacements, according to new research conducted by Paul Williams of Berkeley Lab's Life Sciences Division. http://medicalxpress.com/news/2013-03-excess-doesnt-osteoarthritis-hip.html Arthritis & Rheumatism Fri, 01 Mar 2013 09:00:02 EST news281347443 Proposed cancer therapeutic drugs based on blocking the catalytic activities of matrix metalloproteinases (MMPs), which profoundly remodel the environment surrounding a breast cell, have performed poorly in clinical trials. In mouse studies of MMP14, an enzyme that is often highly expressed in breast cancer, Berkeley Lab researchers have found a possible clue as to why. If confirmed for other MMPs, the finding could point the way to new strategies for future MMP-based cancer therapies. http://medicalxpress.com/news/2013-02-clue-clinical-trial-failures-mmp.html Cancer Tue, 12 Feb 2013 08:09:36 EST news279878956 Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor receptor (EGFR), a cell surface protein that has been strongly linked to a large number of cancers and is a major target of cancer therapies. http://medicalxpress.com/news/2013-02-molecular-machinery-cancer.html Cancer Mon, 11 Feb 2013 15:18:05 EST news279818272 (Medical Xpress)—How's this for big data: A whole-slide image of a tumor section can be ten billion pixels. There can be thousands of such images in the tumor cohorts maintained by The Cancer Genome Atlas project, which are collected from a large pool of patients. http://medicalxpress.com/news/2013-02-pipeline-tumor-images-response-cancer.html Cancer Fri, 01 Feb 2013 06:22:14 EST news278922122 Future research into the underlying causes of neurological disorders such as autism, epilepsy and schizophrenia, should greatly benefit from a first-of-its-kind atlas of gene-enhancers in the cerebrum (telencephalon). This new atlas, developed by a team led by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) is a publicly accessible Web-based collection of data that identifies and locates thousands of gene-regulating elements in a region of the brain that is of critical importance for cognition, motor functions and emotion. http://medicalxpress.com/news/2013-01-genome-wide-atlas-gene-brain-online.html Genetics Thu, 31 Jan 2013 15:00:10 EST news278866544 (Medical Xpress)—There's a reason emergency personnel train for the aftermath of a dirty bomb or an explosion at a nuclear power plant. They'll be faced with a deluge of urgent tasks, such as identifying who's been irradiated, who has an injury-induced infection, and who's suffering from both. http://medicalxpress.com/news/2012-12-scientists-quick-id-people-exposed.html Medical research Mon, 17 Dec 2012 07:34:33 EST news274952067 (Medical Xpress)—There's new hope in the fight against Huntington's disease. A group of researchers that includes scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice. http://medicalxpress.com/news/2012-11-scientists-therapy-huntington-disease.html Neuroscience Thu, 01 Nov 2012 14:49:13 EST news271000132 (Medical Xpress)—Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have identified tissue mechanisms that may influence a woman's susceptibility or resistance to breast cancer after exposure to low-dose ionizing radiation, such as the levels used in full-body CT scans and radiotherapy. http://medicalxpress.com/news/2012-10-ways-id-women-higher-breast.html Cancer Tue, 16 Oct 2012 06:45:32 EST news269588720 A gene that may possibly belong to an entire new family of oncogenes has been linked by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) to the resistance of breast cancer to a well-regarded and widely used cancer therapy. http://medicalxpress.com/news/2012-09-oncogene-future-therapy.html Cancer Tue, 11 Sep 2012 16:24:03 EST news266599428 A new study led by scientists from the Lawrence Berkeley National Laboratory (Berkeley Lab) found that a healthy intake of micronutrients is strongly associated with improved sperm DNA quality in older men. In younger men, however, a higher intake of micronutrients didn't improve their sperm DNA. http://medicalxpress.com/news/2012-08-nutrition-tied-sperm-dna-quality.html Health Mon, 27 Aug 2012 01:00:01 EST news265186817 It is well-known that the risks of breast cancer increase dramatically for women over the age of 50, but what takes place at the cellular level to cause this increase has been a mystery. Some answers and the possibility of preventative measures in the future are provided in a new study by researchers at the DOE's Lawrence Berkeley National Laboratory (Berkeley Lab). http://medicalxpress.com/news/2012-06-aging-breast-cancer-uncover-cellular.html Cancer Mon, 04 Jun 2012 11:57:12 EST news258029819 (Medical Xpress) -- For the past five years, volunteers from the City of Berkeley and surrounding areas have come to Lawrence Berkeley National Laboratory to participate in an ongoing study that’s changing what scientists know about Alzheimer’s disease. http://medicalxpress.com/news/2012-05-earliest-alzheimer.html Alzheimer's disease & dementia Thu, 24 May 2012 08:55:24 EST news257068495 New findings in breast cancer research by an international team of scientists contradict the prevailing belief that only basal-like cells with stem cell qualities can form invasive tumors. Research led by Ole William Petersen at the University of Copenhagen (CU) and Mina Bissell of the Lawrence Berkeley National Laboratory and has shown that luminal-like cells with no detectable stem cell qualities can generate larger tumors than their basal-like counterparts. This may hold important implications for the diagnosis and the treatment of breast cancer as well as future personalized cancer medicine. http://medicalxpress.com/news/2012-04-contradict-current-views-cancer-stem.html Cancer Wed, 18 Apr 2012 12:24:32 EST news253970645 Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation - the linear-no-threshold hypothesis or LNT - which holds that risk is directly proportional to dose at all levels of irradiation. http://medicalxpress.com/news/2011-12-impacts-dose.html Cancer Tue, 20 Dec 2011 13:12:59 EST news243609164