http://medicalxpress.com/ en-us Medical Xpress provides the latest news from Ludwig Maximilian University of Munich (Medical Xpress)—Malignant cells can escape from primary tumors and colonize new sites in other tissues. In a new study, LMU researchers show how the transcription factor AP4 promotes the development of such metastatic tumors. http://medicalxpress.com/news/2013-06-tumor-cells-home.html Cancer Tue, 11 Jun 2013 09:20:02 EST news290159912 When DNA that turns up in the wrong place in mammalian cells, the innate immune system reacts by secreting interferons. The structure and mode of action of the enzyme that mediates this response have now been elucidated. http://medicalxpress.com/news/2013-06-dna.html Medical research Tue, 04 Jun 2013 09:50:01 EST news289557275 Infections can trigger hematopoiesis at sites outside the bone marrow – in the liver, the spleen or the skin. LMU researchers now show that a specific type of immune cell facilitates such "extra medullary" formation of blood cells. http://medicalxpress.com/news/2013-05-herpes-infections-natural-killer-cells.html Medical research Thu, 16 May 2013 10:36:54 EST news287919394 (Medical Xpress)—Atherosclerosis, an inflammatory reaction, is at the root of the most common forms of cardiovascular disease. Researchers at Ludwig-Maximilians-Universitaet in Munich have now identified a microRNA that plays a prominent role in the process, and offers a promising target for new therapies. http://medicalxpress.com/news/2013-03-atherosclerosis-specific-micrornas-inflammation.html Cancer Fri, 22 Mar 2013 13:40:01 EST news283175646 Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death. http://medicalxpress.com/news/2013-03-parkinson-disease-parkin-neuronal-cell.html Parkinson's & Movement disorders Fri, 01 Mar 2013 11:07:03 EST news281358185 LMU researchers led by Christian Weber have, for the first time, elucidated how cells that promote the development of atherosclerosis find their way to the blood vessel wall, where they stimulate the formation of obstructive deposits. http://medicalxpress.com/news/2013-02-monocyte-migrations.html Medical research Tue, 19 Feb 2013 11:50:01 EST news280495879 The innate immune system detects invasive pathogens and activates defense mechanisms to eliminate them. Pathogens, however, employ a variety of tricks to block this process. A new study shows how the measles virus thwarts the system, by means of a simple hairpin-like structure. http://medicalxpress.com/news/2013-01-immune-foiled-hairpin.html Immunology Tue, 22 Jan 2013 05:58:00 EST news278056670 There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target. http://medicalxpress.com/news/2012-11-cancer-therapy-nanokey-tumors.html Cancer Wed, 14 Nov 2012 11:04:22 EST news272113452 Powdered turmeric has been used for centuries to treat osteoarthritis and other illnesses. Its active ingredient, curcumin, inhibits inflammatory reactions. A new study led by a research team at Ludwig-Maximilians-Universität (LMU) in Munich now shows that it can also inhibit formation of metastases. http://medicalxpress.com/news/2012-10-prostate-cancer-curcumin-curbs-metastases.html Cancer Fri, 12 Oct 2012 11:34:26 EST news269260459 Double-stranded breaks in cellular DNA can trigger tumorigenesis. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich, Germany, have determined the structure of a protein involved in the repair and signaling of DNA double-strand breaks. The work throws new light on the origins of neurodegenerative diseases and certain tumor types. http://medicalxpress.com/news/2012-06-detector-dna-factor-revealed.html Medical research Tue, 19 Jun 2012 11:15:09 EST news259323299