http://medicalxpress.com/ en-us Medical Xpress provides the latest news from Mayo Clinic Imaging scans following treatment for diffuse large B-cell lymphoma do little to help detect a relapse, a Mayo Clinic study has found. The overwhelming majority of patients with this aggressive lymphoma already have symptoms, an abnormal physical exam or an abnormal blood test at the time of relapse, the researchers say. The findings will be presented at the American Society of Clinical Oncology annual meeting May 31-June 4 in Chicago. http://medicalxpress.com/news/2013-05-imaging-relapse-aggressive-lymphoma.html Cancer Thu, 16 May 2013 10:57:14 EST news287920615 Using advanced genetic sequencing technology and analysis, Mayo Clinic vaccine researchers have identified 27 genes that respond in very different ways to the standard rubella vaccine, making the vaccine less effective for a portion of the population. The findings appear today in the online journal PLOS ONE. http://medicalxpress.com/news/2013-05-dont-rubella-vaccine.html Immunology Wed, 01 May 2013 17:00:11 EST news286628460 Elderly patients who receive anesthesia are no more likely to develop long-term dementia or Alzheimer's disease than other seniors, according to new Mayo Clinic research. The study analyzed thousands of patients using the Rochester Epidemiology Project—which allows researchers access to medical records of nearly all residents of Olmsted County, Minn.—and found that receiving general anesthesia for procedures after age 45 is not a risk factor for developing dementia. The findings were published Wednesday, May 1, online in Mayo Clinic Proceedings. http://medicalxpress.com/news/2013-04-link-anesthesia-dementia-elderly.html Alzheimer's disease & dementia Wed, 01 May 2013 00:10:01 EST news286564133 Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's activity significantly reduced tumor growth in animals when used alone. Combining it with another drug already used to treat the cancer improved the effectiveness of both. http://medicalxpress.com/news/2013-04-experimental-drug-inhibits-growth-stages.html Cancer Tue, 30 Apr 2013 13:00:02 EST news286536545 Using a one-of-a-kind computer-aided program, Mayo Clinic has developed and implemented a Mayo-wide electronic warning system to identify patients at risk of QT-related deaths from an abnormality in the heart's electrical system. The system informs all physicians, regardless of their specialty or QT awareness, if their patient's ECG activated the QT alarm. In addition, the researchers discovered that the death rate of patients whose 12-lead electrocardiogram (ECG) activated the QT alert was nearly four times greater than all other patients who had an ECG. The findings are published in the current issue of Mayo Clinic Proceedings. http://medicalxpress.com/news/2013-04-mayo-clinic-institution-wide-electronic-prolonged.html Cardiology Thu, 25 Apr 2013 13:04:43 EST news286113833 (Medical Xpress)—A combination of therapies may prove to be a promising advance for the treatment of anaplastic thyroid cancer based on results of a phase I clinical trial, say researchers at Mayo Clinic in Florida. http://medicalxpress.com/news/2013-04-deadly-thyroid-cancer.html Cancer Fri, 19 Apr 2013 08:59:34 EST news285580768 Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor or stem cells—important for repair and regeneration of skeletal muscle and maintenance of healthy fat tissue—are subject to cellular senescence, and that clearance of these cells limits age-related deterioration of these tissues. The findings appear today online in the journal Cell Reports. http://medicalxpress.com/news/2013-04-stem-cell-senescence-aging.html Medical research Thu, 18 Apr 2013 12:42:21 EST news285507734 Good news for anyone needing a transplant; a new Mayo Clinic survey shows that the public's support for both living and deceased organ donation is increasing. Eighty-four percent of respondents said they would be very or somewhat likely to consider donating a kidney or a portion of their liver to a close friend or family member in need, and an astounding 49 percent said they would be very or somewhat likely to consider donating a kidney to someone they have never met, which is often referred to as altruistic or "Good Samaritan" kidney donation. http://medicalxpress.com/news/2013-04-poll-americans-donating-kidney-stranger.html Other Thu, 18 Apr 2013 09:54:37 EST news285497669 How well people are protected by the smallpox vaccine depends on more than the quality of the vaccination: individual genes can alter their response, Mayo Clinic research shows. The findings, gathered using sophisticated genomic screening, appear in today's online issue of the journal Genes and Immunity. http://medicalxpress.com/news/2013-04-smallpox-vaccine-shield-genes.html Genetics Thu, 18 Apr 2013 05:00:01 EST news285437070 Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or "smart" stem cells can improve heart health for people suffering from heart failure. This is the first application in patients of lineage-guided stem cells for targeted regeneration of a failing organ, paving the way to development of next generation regenerative medicine solutions. Results of the clinical trial appear online of the Journal of the American College of Cardiology. http://medicalxpress.com/news/2013-04-cardiopoietic-smart-stem-cells-heart.html Cardiology Wed, 10 Apr 2013 13:19:17 EST news284818748 In a molecular genetic evaluation involving 91 cases of intrauterine fetal death, mutations associated with susceptibility to long QT syndrome (LQTS; a heart disorder that increases the risk for an irregular heartbeat and other adverse events) were discovered in a small number of these cases, preliminary evidence that may provide insights into the mechanism of some intrauterine fetal deaths, according to a study in the April 10 issue of JAMA, a Genomics theme issue. http://medicalxpress.com/news/2013-04-international-heart-disorder-genetic-variants.html Genetics Tue, 09 Apr 2013 16:00:05 EST news284735070 Seemingly benign differences in genetic code from one person to the next could influence who develops side effects to chemotherapy, a Mayo Clinic study has found. The study identified gene variations that can predispose people to chemotherapy-induced peripheral neuropathy, a condition that is hard to predict and often debilitating enough to cause cancer patients to stop their treatment early. Results of the research were presented today at the American Association for Cancer Research Annual Meeting 2013 in Washington, D.C. http://medicalxpress.com/news/2013-04-gene-variations-chemotherapy-side-effects.html Cancer Tue, 09 Apr 2013 10:34:13 EST news284722444 A multidisciplinary team of researchers at Mayo Clinic has developed a new software tool to noninvasively characterize pulmonary adenocarcinoma, a common type of cancerous nodule in the lungs. Results from a pilot study of the computer-aided nodule assessment and risk yield (CANARY) are published in the Journal of Thoracic Oncology. http://medicalxpress.com/news/2013-04-mayo-software-stratifies-posed-lung.html Cancer Mon, 08 Apr 2013 16:01:25 EST news284655674 Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to follow recommendations for providing initial therapy, stem cell transplant and maintenance therapy. The guidelines are published in the current issue of the journal Mayo Clinic Proceedings and represent a consensus opinion of hematologists at Mayo Clinic Cancer Center sites in Minnesota, Florida and Arizona. http://medicalxpress.com/news/2013-04-multiple-myeloma-treatment-guidelines-personalize.html Cancer Mon, 01 Apr 2013 12:23:08 EST news284037777 It appears that the majority of spouses/partners of physicians in the United States are happy with their relationships, according to Mayo Clinic research. Of the about 900 spouses/partners of physicians who responded to a national survey, 85 percent said that they were satisfied in their relationship and 80 percent said they would choose a physician spouse/partner again if they could revisit their choice. These values are similar to those of married adults in the U.S. overall. The study appears in the March edition of Mayo Clinic Proceedings. http://medicalxpress.com/news/2013-03-physician-spouses-relationships.html Other Thu, 28 Mar 2013 12:04:29 EST news283691050