http://medicalxpress.com/ en-us Medical Xpress provides the latest news from Oregon Health & Science University (Medical Xpress)—Patients with two forms of leukemia, who currently have no viable treatment options, may benefit from existing drugs developed for different types of cancer, according to a study conducted by researchers at the Knight Cancer Institute at Oregon Health & Science University (OHSU). http://medicalxpress.com/news/2013-05-discovery-leukemia-insights-treatment-approach.html Cancer Fri, 10 May 2013 12:28:30 EST news287407693 A study published in the most recent version of the journal Obesity found that the body's internal clock, the circadian system, increases hunger and cravings for sweet, starchy and salty foods in the evenings. While the urge to consume more in the evening may have helped our ancestors store energy to survive longer in times of food scarcity, in the current environment of high-calorie food, those late night snacks may result in significant weight gain. http://medicalxpress.com/news/2013-04-triggers-late-night-snack-cravings.html Overweight and Obesity Tue, 30 Apr 2013 09:43:01 EST news286533773 Oregon Health & Science University (OHSU) and Intel Corp. are teaming up to develop next-generation computing technologies that advance the field of personalized medicine by dramatically increasing the speed, precision and cost-effectiveness of analyzing a patient's individual genetic profile. Through a multi-year research and engineering collaboration announced today, engineers and scientists from the two institutions will develop hardware, software and workflow solutions for Intel's extreme-scale, high-performance computing solutions. This new level of computational horsepower seeks to make strides in addressing one of the biggest challenges in personalized medicine: how to cope with the unprecedented volume of complex biomedical data it generates. http://medicalxpress.com/news/2013-04-ohsu-teams-intel-decode-root.html Medical research Mon, 22 Apr 2013 17:30:01 EST news285869807 Researchers have long surmised that management techniques successful in manufacturing and technology sectors may improve health care quality. However, there has been very little evidence about how these practices are disseminated in hospitals and whether they are associated with better performance. http://medicalxpress.com/news/2013-03-toyota-quality-hospital.html Health Tue, 19 Mar 2013 09:43:41 EST news282905015 For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture—using any available technique – until now. http://medicalxpress.com/news/2013-02-team-liver-stem-cells-culture.html Medical research Mon, 25 Feb 2013 16:04:42 EST news281030661 New research from Oregon Health & Science University has provided significant insight into the reasons why early-onset puberty occurs in females. The research, which was conducted at OHSU's Oregon National Primate Research Center, is published in the current early online edition of the journal Nature Neuroscience. http://medicalxpress.com/news/2013-01-epigenetics-early-onset-puberty-females.html Neuroscience Tue, 29 Jan 2013 13:00:56 EST news278686740 Physician-scientists at Oregon Health & Science University Doernbecher Children's Hospital are challenging the way pediatric neurologists think about brain injury in the pre-term infant. In a study published online in the Jan. 16 issue of Science Translational Medicine, the OHSU Doernbecher researchers report for the first time that low blood and oxygen flow to the developing brain does not, as previously thought, cause an irreversible loss of brain cells, but rather disrupts the cells' ability to fully mature. This discovery opens up new avenues for potential therapies to promote regeneration and repair of the premature brain. http://medicalxpress.com/news/2013-01-potential-reverse-disabilities-children-born.html Medical research Thu, 17 Jan 2013 15:26:02 EST news277658747 Researchers at Oregon Health & Science University (OHSU) have found that adults with autism, who represent about 1 percent of the adult population in the United States, report significantly worse health care experiences than their non-autistic counterparts. http://medicalxpress.com/news/2012-12-autistic-adults-significant-shortcomings-health.html Autism spectrum disorders Thu, 06 Dec 2012 13:41:10 EST news274023638 Researchers at Oregon Health & Science University's School of Dentistry have made an important connection between a molecule critical to nerve cells and high blood pressure. Production of the molecule Brain-Derived Neurotrophic Factor (BDNF) appears to increase dramatically in blood pressure-sensing nerve cells during hypertension. The study, published online in the Journal of Neuroscience Research, may someday have implications for the prevention and treatment of high blood pressure, which affects about one in three adults in the United States. http://medicalxpress.com/news/2012-12-molecule-critical-nerve-cells-drammatically.html Neuroscience Thu, 06 Dec 2012 10:42:26 EST news274012931 Researchers at Oregon Health & Science University have discovered that blocking a certain enzyme in the brain can help repair the brain damage associated with multiple sclerosis and a range of other neurological disorders. http://medicalxpress.com/news/2012-10-potential-brain-multiple-sclerosis.html Neuroscience Wed, 31 Oct 2012 14:51:35 EST news270913677 Oregon Health & Science University's development of a new gene therapy method to prevent certain inherited diseases has reached a significant milestone. Researchers at the university's Oregon National Primate Research Center and the OHSU Department of Obstetrics & Gynecology have successfully demonstrated their procedure in human cells. It's believed that this research, along with other efforts, will pave the way for future clinical trials in human subjects. http://medicalxpress.com/news/2012-10-gene-therapy-method-human-cells.html Medical research Wed, 24 Oct 2012 13:29:18 EST news270304141 Physician-scientists at Oregon Health & Science University Doernbecher Children's Hospital have demonstrated for the first time that banked human neural stem cells—HuCNS-SCs, a proprietary product of StemCells Inc.—can survive and make functional myelin in mice with severe symptoms of myelin loss. Myelin is the critical fatty insulation, or sheath, surrounding new nerve fibers and is essential for normal brain function. http://medicalxpress.com/news/2012-10-human-neural-stem-cells-children.html Medical research Wed, 10 Oct 2012 14:00:06 EST news269095269 Nearly 20 percent of people who underwent low back fusion surgery developed post-traumatic stress disorder symptoms associated with that surgery, according to a recent Oregon Health & Science University study published in the journal Spine. http://medicalxpress.com/news/2012-09-one-fifth-spine-surgery-patients-ptsd.html Psychology & Psychiatry Fri, 28 Sep 2012 10:15:54 EST news268046071 Many people with multiple sclerosis for years have taken the natural supplement Gingko biloba, believing it helps them with cognitive problems associated with the disease. http://medicalxpress.com/news/2012-09-gingko-biloba-cognition-ms-patients.html Neuroscience Fri, 14 Sep 2012 09:42:40 EST news266833934 A novel human liver-chimeric mouse model developed at Oregon Health & Science University and Yecuris Corporation has made possible a research breakthrough at Seattle Biomedical Research Institute that will greatly accelerate studies of the most lethal forms of human malaria. http://medicalxpress.com/news/2012-09-humanized-mice-enable-malaria-breakthrough.html Medical research Mon, 10 Sep 2012 16:22:55 EST news266512883