http://medicalxpress.com/ en-us Medical Xpress provides the latest news from Salk Institute A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, published May 14 in the journal Alzheimer's Research and Therapy, may pave the way to a new treatment for Alzheimer's disease in humans. http://medicalxpress.com/news/2013-05-scientists-drug-alzheimer-mice.html Alzheimer's disease & dementia Mon, 13 May 2013 20:00:01 EST news287689272 Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this potentially life-threatening disorder. http://medicalxpress.com/news/2013-05-scientists-potential-therapeutic-cushing-disease.html Diseases, Conditions, Syndromes Tue, 07 May 2013 16:11:18 EST news287161860 Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading to fibrosis include chronic hepatitis virus infection, excess alcohol consumption and, increasingly, nonalcoholic steatohepatitis (NASH). http://medicalxpress.com/news/2013-04-sunshine-hormone-vitamin-d-liver.html Medical research Thu, 25 Apr 2013 14:55:15 EST news286120272 The irony of getting away to a remote place is you usually have to fight traffic to get there. After hours of dodging dangerous drivers, you finally arrive at that quiet mountain retreat, stare at the gentle waters of a pristine lake, and congratulate your tired self on having "turned off your brain." http://medicalxpress.com/news/2013-04-brain-mathematical-genius.html Neuroscience Thu, 11 Apr 2013 10:49:11 EST news284896135 Ever find yourself racking your brain on a Monday morning to remember where you put your car keys? When you do find those keys, you can thank the hippocampus, a brain region responsible for storing and retrieving memories of different environments-such as that room where your keys were hiding in an unusual spot. http://medicalxpress.com/news/2013-03-neuroscience-lost-keys.html Neuroscience Thu, 21 Mar 2013 09:26:00 EST news283076722 Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer. http://medicalxpress.com/news/2013-01-diabetes-drug-lung-cancer-patients.html Cancer Tue, 29 Jan 2013 10:06:14 EST news278676360 (Medical Xpress)—When it's dark, and we start to fall asleep, most of us think we're tired because our bodies need rest. Yet circadian rhythms affect our bodies not just on a global scale, but at the level of individual organs, and even genes. http://medicalxpress.com/news/2012-12-epigenetic-daily-liver.html Genetics Tue, 11 Dec 2012 08:46:51 EST news274437981 Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's. http://medicalxpress.com/news/2012-10-diabetes-proteins-linked-alzheimer-features.html Alzheimer's disease & dementia Fri, 26 Oct 2012 09:42:42 EST news270463247 Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ally in the fight against cancer. http://medicalxpress.com/news/2012-10-cold-viruses-cancer-therapies.html Cancer Tue, 16 Oct 2012 17:27:26 EST news269627232 Scientists have known for some time that throwing off the body's circadian rhythm can negatively affect body chemistry. In fact, workers whose sleep-wake cycles are disrupted by night shifts are more susceptible to chronic inflammatory diseases such as diabetes, obesity and cancer. http://medicalxpress.com/news/2012-08-molecular-link-circadian-clock-disturbances.html Medical research Wed, 01 Aug 2012 09:19:47 EST news263031580 For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood and metabolic diseases. http://medicalxpress.com/news/2012-07-neurons-derived-cord-blood-cells.html Medical research Mon, 16 Jul 2012 16:22:15 EST news261674525 The hormone oxytocin - often referred to as the "trust" hormone or "love hormone" for its role in stimulating emotional responses - plays an important role in Williams syndrome (WS), according to a study published June 12, 2012, in PLoS One. http://medicalxpress.com/news/2012-06-hormone-oxytocin-heart-rare-genetic.html Neuroscience Fri, 22 Jun 2012 15:05:41 EST news259596331 It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override the adverse health effects of a high-fat diet and prevent obesity, diabetes and liver disease in mice. http://medicalxpress.com/news/2012-05-drug-free-intervention-obesity-diabetes.html Medical research Thu, 17 May 2012 12:00:19 EST news256474173 Humans are built to hunger for fat, packing it on during times of feast and burning it during periods of famine. But when deluged by foods rich in fat and sugar, the modern waistline often far exceeds the need to store energy for lean times, and the result has been an epidemic of diabetes, heart disease and other obesity-related problems. http://medicalxpress.com/news/2012-04-feast-famine-metabolic-diabetes-treatment.html Medical research Wed, 25 Apr 2012 09:19:06 EST news254564308 In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose -- the simple sugar that is the source of energy in human cells and the central player in diabetes. http://medicalxpress.com/news/2012-04-molecular-liver-glucose-production-ii.html Medical research Sun, 08 Apr 2012 13:00:29 EST news253084650