http://medicalxpress.com/ en-us Medical Xpress provides the latest news from University Health Network A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant. http://medicalxpress.com/news/2013-04-breast-cancer-drug-companion-prognostic.html Cancer Mon, 01 Apr 2013 15:00:01 EST news284032748 A team of Canadian and international cancer researchers led by Dr. Brenda Gallie at the Princess Margaret Cancer Centre, University Health Network (UHN), has discovered a new type of retinoblastoma, a rapidly developing eye cancer that affects very young babies– a finding that can immediately change clinical practice and optimize care for these children. http://medicalxpress.com/news/2013-03-cancer-retinoblastoma-babies.html Cancer Tue, 12 Mar 2013 20:20:01 EST news282333102 In a world first, a team of researchers at the Krembil Neuroscience Centre and the University Health Network have shown that Deep Brain Stimulation (DBS) in patients with chronic, severe and treatment-resistant Anorexia Nervosa (anorexia) helps some patients achieve and maintain improvements in body weight, mood, and anxiety. http://medicalxpress.com/news/2013-03-deep-brain-patients-chronic-treatment.html Psychology & Psychiatry Wed, 06 Mar 2013 18:30:01 EST news281808694 An international team of tropical medicine researchers have discovered a potential method for preventing low birth weight in babies born to pregnant women who are exposed to malaria. Low birth weight is the leading cause of infant death globally. http://medicalxpress.com/news/2013-02-infant-deaths.html Medical research Wed, 13 Feb 2013 12:00:02 EST news279977753 In recent weeks the intensive critical care units at University Health Network's Toronto General Hospital have used Extra Corporeal Lung Support (ECLS) to support five influenza (flu) patients in their recovery from severe respiratory problems. http://medicalxpress.com/news/2013-01-critically-ill-flu-patients-artificial.html Diseases, Conditions, Syndromes Thu, 17 Jan 2013 12:57:59 EST news277649196 Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumour cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal cancer, they found that genetic mutations, regarded by many as the chief suspect driving cancer growth, are only one piece of the puzzle. The team discovered that biological factors and cell behaviour – not only genes – drive tumour growth, contributing to therapy failure and relapse. http://medicalxpress.com/news/2012-12-scientists-layer-complexity-colon-cancer.html Cancer Thu, 13 Dec 2012 14:00:12 EST news274621789 A team of Canadian scientists and clinicians, led by Dr. Michael Hill of the Calgary Stroke Program at Foothills Medical Centre and University of Calgary's Hotchkiss Brain Institute (HBI), have demonstrated that a neuroprotectant drug, developed by Dr. Michael Tymianski at the Krembil Neuroscience Centre, located at the Toronto Western Hospital, protects the human brain against the damaging effects of stroke. http://medicalxpress.com/news/2012-10-world-successful-clinical-trial-brain.html Neuroscience Tue, 09 Oct 2012 10:10:01 EST news268994722 A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme and the onset of acute myeloid leukemia (AML), one of the most common types of leukemia in adults. http://medicalxpress.com/news/2012-07-scientists-link-oncometabolite-onset-acute.html Cancer Wed, 04 Jul 2012 13:09:40 EST news260626161 Physicians can reduce the number of heart failure deaths and unnecessary hospital admissions by using a new computer-based algorithm developed at the Institute for Clinical Evaluative Sciences (ICES) that calculates each patient's individual risk of death. Published in the Annals of Internal Medicine, the algorithm improves upon clinical decision-making and determines whether or not a patient with heart failure should be admitted to hospital. To bring this tool into the emergency departments, Peter Munk Cardiac Centre cardiologists are developing smartphone and web-based applications to assist physicians in the emergency department to determine patients' numerical risk score in real time. http://medicalxpress.com/news/2012-06-emergency-department-algorithm-death-heart.html Cardiology Mon, 04 Jun 2012 17:00:10 EST news258044648