http://medicalxpress.com/ en-us Medical Xpress provides the latest news from University of California, Irvine UC Irvine Health urologists and health policy experts report in a new study that two written assessments that identify existing comorbidities – the patient-reported Total Illness Burden Index for Prostate Cancer (TIBI-Cap) and the physician-reported Charlson Comorbidity Index – can successfully target prostate patients who would not benefit from biopsy to discover possible cancer. http://medicalxpress.com/news/2013-05-comorbidities-factor-prostate-biopsy-choice.html Cancer Wed, 15 May 2013 09:18:45 EST news287828319 UC Irvine neurobiologists have found a novel molecular mechanism that helps trigger the formation of long-term memory. The researchers believe the discovery of this mechanism adds another piece to the puzzle in the ongoing effort to uncover the mysteries of memory and, potentially, certain intellectual disabilities. http://medicalxpress.com/news/2013-03-mechanism-long-term-memory-formation.html Neuroscience Mon, 25 Mar 2013 12:35:44 EST news283433738 (Medical Xpress)—Positive emotions are known to play a role in physical well-being, and stress is strongly linked to poor health, but is this strictly a "First World" phenomenon? In developing nations, is the fulfillment of basic needs more critical to health than how one feels? A UC Irvine researcher has found that emotions do affect health around the world and may, in fact, be more important to wellness in low-income countries. http://medicalxpress.com/news/2013-03-emotion-health-limited-wealthy-nations.html Psychology & Psychiatry Fri, 08 Mar 2013 09:19:32 EST news281956766 (Medical Xpress)—UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment approach, as mutant forms of this protein are implicated in nearly 40 percent of diagnosed cases of cancer, which kills more than half a million Americans each year. http://medicalxpress.com/news/2013-01-wide-spectrum-cancers.html Cancer Thu, 31 Jan 2013 08:40:04 EST news278842249 Exposing pregnant mice to low doses of the chemical tributyltin (TBT) – which was used in marine antifouling paints and is used as an antifungal agent in some paints, certain plastics and a variety of consumer products – can lead to obesity for multiple generations without subsequent exposure, a UC Irvine study has found. http://medicalxpress.com/news/2013-01-fetal-exposure-tributyltin-linked-obesity.html Overweight and Obesity Thu, 24 Jan 2013 16:42:02 EST news278268114 UC Irvine neuroscientists have developed a way to stop epileptic seizures with fiber-optic light signals, heralding a novel opportunity to treat the most severe manifestations of the brain disorder. http://medicalxpress.com/news/2013-01-neuroscientists-fiber-optic-method-epileptic-seizures.html Neuroscience Thu, 24 Jan 2013 12:54:51 EST news278254478 (Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control this action. The findings point to potential treatments for disorders triggered by circadian rhythm dysfunction, ranging from insomnia and obesity to diabetes and cancer. http://medicalxpress.com/news/2013-01-circadian-rhythms-potential-treatment-disorders.html Cardiology Tue, 22 Jan 2013 15:12:20 EST news278089921 Exposing pregnant mice to low doses of the chemical tributyltin – which is used in marine hull paint and PVC plastic – can lead to obesity for multiple generations without subsequent exposure, a UC Irvine study has found. http://medicalxpress.com/news/2013-01-fetal-exposure-pvc-plastic-chemical.html Health Tue, 15 Jan 2013 00:00:08 EST news277404251 A study led by UC Irvine researchers has revealed some of the underlying neural factors that explain why people with Down syndrome are more susceptible to Alzheimer's disease, diabetes and autistic spectrum disorders. http://medicalxpress.com/news/2013-01-uci-reveals-syndrome-boosts-susceptibility.html Alzheimer's disease & dementia Fri, 11 Jan 2013 09:13:07 EST news277117981 (Medical Xpress)—A variant of a gene associated with active personality traits in humans seems to also be involved with living a longer life, UC Irvine and other researchers have found. http://medicalxpress.com/news/2013-01-dopamine-receptor-gene-variant-linked-human.html Neuroscience Thu, 03 Jan 2013 15:05:41 EST news276447934 A UC Irvine researcher is part of a NASA effort to understand more about bone density loss during astronauts' lengthy stays aboard the International Space Station. http://medicalxpress.com/news/2012-12-uci-radiology-aid-nasa-bone.html Diseases, Conditions, Syndromes Mon, 10 Dec 2012 15:59:56 EST news274377587 (Medical Xpress)—A short burst of moderate exercise enhances the consolidation of memories in both healthy older adults and those with mild cognitive impairment, scientists with UC Irvine's Center for the Neurobiology of Learning & Memory have discovered. http://medicalxpress.com/news/2012-11-immediately-memory.html Neuroscience Tue, 27 Nov 2012 07:34:20 EST news273224053 UC Irvine oncologists are looking for new ways to treat glioblastoma multiforme, the deadliest type of brain cancer. While surgery followed by chemotherapy and radiation is the current standard of care, it doesn't fully eliminate the cancer. The goal is to develop an additional therapy that seeks out and destroys the cancer cells that inevitably remain. http://medicalxpress.com/news/2012-11-brain-cancer-breakthrough-experimental-vaccine.html Cancer Wed, 14 Nov 2012 08:22:21 EST news272103731 (Medical Xpress)—Ask most people to describe a telescope and they might imagine a large device in an observatory training its penetrating gaze into outer space. http://medicalxpress.com/news/2012-11-year-old-implant-vision-lost-macular.html Ophthalmology Fri, 09 Nov 2012 06:48:53 EST news271666095 (Medical Xpress)—UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer's. http://medicalxpress.com/news/2012-11-cell-treatment-alzheimer-brain-diseases.html Neuroscience Wed, 07 Nov 2012 12:54:18 EST news271515250