http://medicalxpress.com/ en-us Medical Xpress provides the latest news from University of Montreal A new Montréal study conducted by Dr. May Faraj, associate research professor at the Université de Montréal and invited scientist at the IRCM, along with her research team and medical collaborators, shows that the number of particles carrying bad cholesterol in the blood is an important factor in promoting the risk for type 2 diabetes in obese individuals. Their results are published in the May issue of the Journal of Lipid Research. This scientific breakthrough may help prevent diabetes by targeting treatments to higher-risk individuals. http://medicalxpress.com/news/2013-05-mechanism-diabetes-obese-individuals.html Medical research Fri, 17 May 2013 09:00:05 EST news287997845 (Medical Xpress)—A team led by Dr. Alex Parker, a professor of pathology and cellular biology and a researcher at the University of Montreal Hospital Research Centre (CRCHUM), has identified an important therapeutic target for alleviating the symptoms of Lou Gehrig's disease, also known as amyotrophic lateral sclerosis (ALS), and other related neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and Huntington's disease. http://medicalxpress.com/news/2013-04-treatment-possibilities-lou-gehrig-disease.html Neuroscience Wed, 17 Apr 2013 08:46:18 EST news285407131 Canadians and patients around the world with the misfortune to be diagnosed with one of the deadliest forms of leukemia may soon be able to thank a multi-faceted collaboration in Montreal's biopharmaceutical cluster for giving them new hope against their blood cancer. http://medicalxpress.com/news/2013-04-academia-industry-partnership-blueprint-collaboration-cancer.html Cancer Fri, 12 Apr 2013 09:00:03 EST news284975386 Researchers at the University of Montreal have found that the glycated hemoglobin levels of children with type 1 diabetes followed at its affiliated Sainte-Justine Mother and Child University Hospital (CHU Sainte-Justine) is correlated linearly and negatively with household income. Glycated hemoglobin is the binding of sugar to blood molecules – over time, high blood sugar levels lead to high levels of glycated hemoglobin, which means that it can be used to assess whether a patient properly controls his or her blood glucose level. "Our study highlights a marked disparity between the rich and the poor in an important health outcome for children with type 1 diabetes, despite free access to health care", explained Dr. Johnny Deladoëy, who led the study. http://medicalxpress.com/news/2013-04-free-health-household-income-affects.html Diabetes Thu, 04 Apr 2013 04:50:01 EST news284268945 University of Montreal researchers have discovered a novel molecular mechanism that can potentially slows the aging process and may prevent the progression of some cancers. In the March 23 online edition of the prestigious journal Aging Cell, scientists from the University of Montreal explain how they found that the antidiabetic drug metformin reduces the production of inflammatory cytokines that normally activate the immune system, but if overproduced can lead to pathological inflammation, a condition that both damages tissues in aging and favors tumor growth. http://medicalxpress.com/news/2013-03-team-drug-aging-cancer.html Medical research Wed, 27 Mar 2013 05:16:50 EST news283579998 Three myths about sleepwalking – sleepwalkers have no memory of their actions, sleepwalkers' behaviour is without motivation, and sleepwalking has no daytime impact – are dispelled in a recent study led by Antonio Zadra of the University of Montreal and its affiliated Sacré-Coeur Hospital. Working from numerous studies over the last 15 years at the hospital's Centre for Advanced Studies in Sleep Medicine at the Hôpital du Sacré-Cœur de Montréal and a thorough analysis of the literature, Zadra and his colleagues have raised the veil on sleepwalking and clarified the diagnostic criteria for researchers and clinicians. http://medicalxpress.com/news/2013-03-sleepwalkers-theyve.html Neuroscience Thu, 14 Mar 2013 04:45:56 EST news282455141 Researchers at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC) have discovered a new mechanism that allows some cells in our body to move together, in some ways like the tortoise formation used by Roman soldiers depicted in the Asterix series. Collective cell migration is an essential part of our body's growth and defense system, but it is also used by cancerous cells to disseminate efficiently in the body. "We have found a key mechanism that allows cells to coordinate their movement as a group and we believe that this mechanism is used by malignant cells in a number of cancers, including some types of breast, prostate and skin cancers" explained lead researcher Gregory Emery. Roman soldiers formed the tortoise, or testudo formation, by coming closely together and aligning their shields side-by-side in order to defend themselves as they broke their enemy lines. http://medicalxpress.com/news/2013-03-asterix-roman-foes-idea-cancer.html Cancer Tue, 12 Mar 2013 05:06:36 EST news282283586 Families with a child completing elementary school this year are now preparing their registration for high school, a transition that is often stressful for children. A new program has demonstrated that it is possible to significantly reduce stress in some of these children thanks to a new educational tool designed under the leadership of Sonia Lupien, Director of the Centre for Studies on Human Stress (CSHS) and professor at the University of Montreal. http://medicalxpress.com/news/2013-03-stress-teenagers.html Psychology & Psychiatry Mon, 11 Mar 2013 11:45:31 EST news282221092 A single dose of an investigational anti-inflammatory drug called inclacumab considerably reduces damage to heart muscle during angioplasty (the opening of a blocked artery), according to a recent international clinical trial spearheaded by Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, affiliated with the University of Montreal. Presented today in San Francisco at the prestigious American cardiology conference, these findings show great promise. http://medicalxpress.com/news/2013-03-drug-inclacumab-heart.html Cardiology Sun, 10 Mar 2013 14:30:01 EST news282138621 For chronic pain sufferers, such as people who develop back pain after a car accident, avoiding the harmful effects of stress may be key to managing their condition. This is particularly important for people with a smaller-than-average hippocampus, as these individuals seem to be particularly vulnerable to stress. http://medicalxpress.com/news/2013-02-chronic-pain-stress.html Neuroscience Mon, 25 Feb 2013 04:08:10 EST news280987682 Using genome-wide analysis, investigators at the Sainte-Justine University Hospital Research Center and the University of Montreal have potentially eliminated a lifetime drug prescription that two children with a previously unknown type of adrenal insufficiency had been receiving for 14 years. http://medicalxpress.com/news/2013-01-personalized-medicine-drug-children.html Genetics Thu, 31 Jan 2013 12:58:00 EST news278859472 English Premier League soccer players, NHL hockey players, France's Top 14 club rugby players, and even elite amateur athletes have better developed cognitive functions than the average university student, according to a perception study undertaken by Professor Jocelyn Faubert of the University of Montreal's School of Optometry. http://medicalxpress.com/news/2013-01-jocks-bookworms-brain.html Psychology & Psychiatry Thu, 31 Jan 2013 09:00:01 EST news278825968 Lesbians, gays and bisexuals (LGBs) who are out to others have lower stress hormone levels and fewer symptoms of anxiety, depression, and burnout, according to researchers at the Centre for Studies on Human Stress (CSHS) at Louis H. Lafontaine Hospital, affiliated with the University of Montreal. http://medicalxpress.com/news/2013-01-health-benefits-closet.html Psychology & Psychiatry Tue, 29 Jan 2013 00:10:01 EST news278613398 In a study published in the very first issue of the new journal JAMA Psychiatry, researchers from Sainte-Justine University Hospital Center, University of Montreal and King's College London have shown that personality-targeted school interventions delivered to high risk adolescents manage to reduce and postpone problem drinking, which is responsible for 9% of the deaths in young people between the ages of 15 and 29 in developed countries. Furthermore, by delaying alcohol uptake in at-risk youth, low-risk youth apparently gain group immunity due to reduced drinking within their social network. http://medicalxpress.com/news/2013-01-teenagers-early-alcohol-misuse-personality.html Psychology & Psychiatry Wed, 23 Jan 2013 16:41:04 EST news278181489 Older adults who have suffered from aphasia for a long time can nevertheless improve their language function and maintain these improvements in the long term, according to a study by Dr. Ana Inés Ansaldo, PhD, a researcher at the Research Centre of the Institut universitaire de gériatrie de Montréal (University Geriatrics Institute of Montreal) and a professor in the School of Speech-Language Pathology and Audiology at the Faculty of Medicine of Université de Montréal. The study was published in Brain and Language. http://medicalxpress.com/news/2013-01-intensive-aphasia-older-patients.html Neuroscience Wed, 09 Jan 2013 04:33:12 EST news276928315