http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—How's this for big data: A whole-slide image of a tumor section can be ten billion pixels. There can be thousands of such images in the tumor cohorts maintained by The Cancer Genome Atlas project, which are collected from a large pool of patients. http://medicalxpress.com/news/2013-02-pipeline-tumor-images-response-cancer.html Cancer Fri, 01 Feb 2013 06:22:14 EST news278922122 Cancer arises from the accumulation of mutations and structural changes in chromosomes, which in some cases give rise to combinations that favour the growth or expansion of the disease. In this context, chromosomes tend to lose or duplicate entire regions, although, the mechanisms that initiate these chromosomal abnormalities are not fully understood. http://medicalxpress.com/news/2013-01-mechanism-contributes-evolution-cancer.html Cancer Thu, 31 Jan 2013 12:59:19 EST news278859506 Facebook activity provided a window into the psychological health of participants in a study at the University of Missouri. Social media profiles could eventually be used as tools for psychologists and therapists, according to study leader Elizabeth Martin, doctoral student in MU's psychological science department in the College of Arts and Science. http://medicalxpress.com/news/2013-01-analysis-social-media-therapists-view.html Psychology & Psychiatry Fri, 25 Jan 2013 09:12:51 EST news278327553 Fusion genes are common chromosomal aberrations in many cancers, and can be used as prognostic markers and drug targets in clinical practice. http://medicalxpress.com/news/2013-01-fusion-gene-contributes-glioblastoma.html Cancer Wed, 09 Jan 2013 13:07:49 EST news276959258 Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients are highly responsive to ALK-specific kinase inhibitors such as crizotinib. However, current diagnostic tests have limitations. Researchers have now developed and tested a promising new method for screening ALK fusions in NSCLC. This new diagnostic assay offers a cost-effective and easy-to-perform alternative to existing tests. The study is published in The Journal of Molecular Diagnostics. http://medicalxpress.com/news/2012-12-patients-benefit-alk-inhibition-therapy.html Medical research Wed, 12 Dec 2012 12:04:53 EST news274536268 Cancer patients with mutations or variations in two genes -– PIK3CA and PTEN -– who have failed to respond to several, standard treatments, respond significantly better to anti-cancer drugs that inhibit these genes' pathways of action, according to research presented at the 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland, today. http://medicalxpress.com/news/2012-11-patients-aberrations-genes-drugs-blocking.html Cancer Wed, 07 Nov 2012 18:27:28 EST news271535236 Two different genetic mutations cooperate to induce adrenal cancer, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center and University of Sao Paulo in Brazil. http://medicalxpress.com/news/2012-09-gene-mutations-adrenal-cancer.html Cancer Mon, 10 Sep 2012 16:32:44 EST news266513523 Prostate cancer is generally treated as if it's a single disease. But researchers have discovered a new type of the cancer that appears to affect 15 percent of patients, a finding that paves the way for better diagnosis and more targeted therapies down the road. http://medicalxpress.com/news/2012-09-gene-mutation-proteins-tumor-growth.html Cancer Fri, 07 Sep 2012 13:47:08 EST news266244418 Scientists have successfully sequenced the genome of a baby in the womb without tapping its protective fluid sac. This non-invasive approach to obtaining the fetal genome is reported in the June 6 issue of Science Translational Medicine. http://medicalxpress.com/news/2012-06-baby-genome-deciphered-prenatally-parents.html Genetics Wed, 06 Jun 2012 14:00:02 EST news258208291 According to a new study, children exposed to high levels of the common air pollutant naphthalene are at increased risk for chromosomal aberrations (CAs), which have been previously associated with cancer. These include chromosomal translocations, a potentially more harmful and long-lasting subtype of CAs. http://medicalxpress.com/news/2012-05-children-exposed-common-pollutant-naphthalene.html Health Tue, 29 May 2012 13:06:31 EST news257515517 A healthy genome is characterized by 23 pairs of chromosomes, and even a small change in this structure — such as an extra copy of a single chromosome — can lead to severe physical impairment. So it's no surprise that when it comes to cancer, chromosomal structure is frequently a contributing factor, says Prof. Ron Shamir of the Blavatnik School of Computer Science at Tel Aviv University. http://medicalxpress.com/news/2012-01-patterns-chromosome-abnormality-key-cancer.html Cancer Mon, 23 Jan 2012 12:35:39 EST news246544470 Despite advances in both the diagnosis and treatment of breast cancer, the disease remains a leading worldwide health concern. http://medicalxpress.com/news/2012-01-cell-ct-dimension-breast-cancer.html Cancer Thu, 05 Jan 2012 17:29:18 EST news245006944 The founder of the French breast implant maker at the centre of a global health scare said Thursday much of the information emerging in the scandal was untrue but refused further comment. http://medicalxpress.com/news/2012-01-french-breast-implant-maker-denounces.html Other Thu, 05 Jan 2012 13:19:15 EST news244991950 Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry and the Silver Child Development Center. http://medicalxpress.com/news/2012-01-autism-linked-abnormal-immune-characteristics.html Immunology Tue, 03 Jan 2012 14:16:17 EST news244822569 As cancer researchers continue to identify genetic mutations driving different cancer subtypes, they are also creating a catalog of possible targets for new treatments. http://medicalxpress.com/news/2011-11-genetic-sequencing-patients-biomarker-driven-cancer.html Cancer Wed, 30 Nov 2011 14:00:02 EST news241880763