http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—Using the fruit fly as a model organism, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have identified the L1-type CAM neuroglian as an important regulator for synapse growth, function and stability. They show that the interaction of neuroglian with ankyrin provides a regulatory module to locally control synaptic connectivity and function. http://medicalxpress.com/news/2013-04-scientists-important-synapse-stability-plasticity.html Neuroscience Thu, 25 Apr 2013 07:59:47 EST news286095579 Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor College of Medicine in a report that appears online in the journal Science Translational Medicine. http://medicalxpress.com/news/2013-04-signature-circulating-breast-tumor-cells.html Cancer Wed, 10 Apr 2013 14:00:02 EST news284818141 (HealthDay)—For patients with type 1 diabetes mellitus, elevated levels of high-sensitivity C-reactive protein (hsCRP) are associated with an increased risk of clinically significant macular edema (CSME) and with the development of retinal hard exudates, according to a study published online Feb. 7 in JAMA Ophthalmology. http://medicalxpress.com/news/2013-02-high-hscrp-macular-edema-t1dm.html Ophthalmology Fri, 08 Feb 2013 14:10:01 EST news279552940 A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of the protein with monoclonal antibodies reduced the size of tumors, lowered the occurrence of metastases and substantially lengthened survival time. The findings will be published in the November issue of Cancer Research. http://medicalxpress.com/news/2012-11-scientists-lung-cancer-treatment.html Cancer Thu, 01 Nov 2012 15:11:39 EST news271001442 The 7.5 millilitres of blood contained in a standard sample tube is not nearly enough to detect circulating tumour cells (CTCs) in the blood of patients with metastatic breast cancer, prostate cancer, or colorectal cancer with a high enough degree of reliability. These CTCs are the cause of metastases in cancer patients. If they can be effectively characterized, it is possible to arrive at a prognosis and to determine the most effective course of treatment. However, the only way to detect "that one particular cell" is to subject the patient's entire blood volume to a kind of dialysis. This was the conclusion reached by Dr Frank Coumans in an article published in the journal Clinical Cancer Research. Dr Coumans works at the University of Twente's MIRA Institute for Biomedical Technology and Technical Medicine. He was recently awarded a PhD (with distinction) on this topic. http://medicalxpress.com/news/2012-10-tumour-cell.html Cancer Mon, 29 Oct 2012 10:10:03 EST news270723176 (HealthDay)—The cell surface marker carcinoembryonic antigen-related cell adhesion molecule 6 (CD66c) is a novel marker for colorectal cancer stem cell isolation, which halts tumor growth when silenced, according to research published online Oct. 1 in Cancer. http://medicalxpress.com/news/2012-10-potential-colorectal-cancer-treatment.html Cancer Sun, 07 Oct 2012 14:14:26 EST news268838053 New research could clarify how inflammatory bowel diseases (IBD), conditions that include ulcerative colitis and Crohn's disease, are triggered and develop. http://medicalxpress.com/news/2012-09-immune-compensates-leaky-gut-inflammatory.html Immunology Thu, 13 Sep 2012 12:56:26 EST news266759776 (Medical Xpress)—By administering a simple behavioral test, Yale researchers were able to predict which mice would later exhibit alcoholism-related behaviors such as the inability to stop seeking alcohol and a tendency to relapse, the scientists report in the Aug. 26 issue of the journal Nature Neuroscience. http://medicalxpress.com/news/2012-08-behavioral-future-problems-alcohol.html Neuroscience Mon, 27 Aug 2012 08:29:22 EST news265274950 those disc-shaped cells circulating in your blood -- rush to the scene, clumping together to plug the leak. http://medicalxpress.com/news/2012-05-jam-a-protein-blood-clots.html Medical research Thu, 03 May 2012 11:00:01 EST news255260481 (Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller percentage of people with almost every other type of cancer. Beta-catenin plays a dual role in the cell: it promotes adhesion, or stickiness, between cells, and regulates the expression of genes in the nucleus. http://medicalxpress.com/news/2012-05-outwitting-brainy-gene.html Cancer Tue, 01 May 2012 10:40:01 EST news255084489 Creating a radioactive antibody fragment may allow scientists to identify fat and debris deposits in artery walls that are most likely to rupture and cause heart attacks, according to a new study in Circulation: Research, an American Heart Association journal. http://medicalxpress.com/news/2012-03-radioactive-antibody-fragment-scientists-artery.html Cardiology Thu, 29 Mar 2012 16:38:22 EST news252257877 A new study by University of Kentucky researchers provides insight into developing new treatment strategies for basal-like breast cancer, commonly known as triple-negative breast cancer. This cancer is associated with early metastasis and resistance to chemotherapy and occurs at women at a younger age. http://medicalxpress.com/news/2012-03-treatments-breast-cancer.html Cancer Wed, 14 Mar 2012 11:23:53 EST news250943025 Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed Central's open access journal Cell Communication and Signaling demonstrates how IBC cells use IL-8, secreted as part of the anti-inflammatory response by a specific set of white blood cells (monocytes), to increase fibronectin expression. http://medicalxpress.com/news/2012-02-metastatic-breast-cancer-hitches-free.html Immunology Fri, 10 Feb 2012 05:30:01 EST news248073643