http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. University of Montreal researchers have discovered a novel molecular mechanism that can potentially slows the aging process and may prevent the progression of some cancers. In the March 23 online edition of the prestigious journal Aging Cell, scientists from the University of Montreal explain how they found that the antidiabetic drug metformin reduces the production of inflammatory cytokines that normally activate the immune system, but if overproduced can lead to pathological inflammation, a condition that both damages tissues in aging and favors tumor growth. http://medicalxpress.com/news/2013-03-team-drug-aging-cancer.html Medical research Wed, 27 Mar 2013 05:16:50 EST news283579998 A drug widely used to treat Parkinson's Disease can help to reverse age-related impairments in decision making in some older people, a study from researchers at the Wellcome Trust Centre for Neuroimaging has shown. http://medicalxpress.com/news/2013-03-parkinsons-drug-older-people-decisions.html Neuroscience Sun, 24 Mar 2013 14:00:13 EST news283334994 (Medical Xpress)—The contrasting nature of facial features is one of the signals that people unconsciously use to decipher how old someone looks, says Psychology Prof. Richard Russell, who has been collaborating with researchers from CE.R.I.E.S. (Epidermal and Sensory Research and Investigation Center), a department of Chanel Research and Technology dedicated to skin related issues and facial appearance. http://medicalxpress.com/news/2013-03-psychology-reveals-aging-perception.html Psychology & Psychiatry Sun, 17 Mar 2013 19:00:01 EST news282764668 Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide energy for muscle contraction, and their fragmentation within muscle cells can lead to muscle wasting. Now, a team of researchers led by Ravi Kambadur at the A*STAR Singapore Institute for Clinical Sciences has identified a key role for mitochondrial E3 ubiquitin protein ligase 1 (Mul1) in mitochondrial fragmentation. Such fragmentation occurs in response to stimuli that cause muscle loss. http://medicalxpress.com/news/2013-03-cell-metabolism-muscle-loss-mitochondrial.html Medical research Wed, 13 Mar 2013 08:00:01 EST news282379201 In the early 1990s, MIT professor Leonard Guarente discovered that sirtuins, a class of proteins found in nearly all animals, protect against the effects of aging in yeast; similar effects have since been seen in many other organisms. In 2003, David Sinclair, who had been a postdoc in Guarente's lab, found that resveratrol, a compound found in grapes and red wine, can also counteract the effects of aging. Since then, many scientists have tried to tease out the exact relationship among sirtuins, resveratrol and aging. http://medicalxpress.com/news/2013-03-mit-biologist-resveratrol.html Medical research Thu, 07 Mar 2013 16:47:20 EST news281897232 Research shows that married people have better mental and physical health than their unmarried peers and are less likely to develop chronic conditions than their widowed or divorced counterparts. A University of Missouri expert says that people who have happy marriages are more likely to rate their health as better as they age; aging adults whose physical health is declining could especially benefit from improving their marriages. http://medicalxpress.com/news/2013-02-happily-couples-healthier-expert.html Psychology & Psychiatry Wed, 13 Feb 2013 14:10:03 EST news279986393 Researchers from Inserm and the Université Lille/Université Lille Nord de France have recently used a neurodegeneration model of Alzheimer's disease to provide experimental evidence of the relationship between obesity and disorders linked to the tau protein. This research was conducted on mice and is published in the Diabetes Review. It corroborates the theory that metabolic anomalies contribute massively to the development of dementia. http://medicalxpress.com/news/2013-01-detrimental-effect-obesity-lesions-alzheimer.html Alzheimer's disease & dementia Mon, 07 Jan 2013 12:30:41 EST news276784231 Scientists at the Gladstone Institutes have identified a novel mechanism by which a type of low-carb, low-calorie diet—called a "ketogenic diet"—could delay the effects of aging. This fundamental discovery reveals how such a diet could slow the aging process and may one day allow scientists to better treat or prevent age-related diseases, including heart disease, Alzheimer's disease and many forms of cancer. http://medicalxpress.com/news/2012-12-gladstone-scientists-mechanism-calorie-restriction.html Medical research Thu, 06 Dec 2012 14:23:32 EST news274026168 Old age comes faster and hits harder for those infected with HIV, a fact aging health activist Ron Swanda knows all too well. http://medicalxpress.com/news/2012-11-activist-discusses-hiv.html HIV & AIDS Fri, 30 Nov 2012 07:04:57 EST news273481483 A simple six-question quiz, typically used to assess disabilities in the elderly, could help doctors determine which kidney dialysis patients of any age are at the greatest risk of death, new Johns Hopkins research suggests. http://medicalxpress.com/news/2012-10-quiz-elderly-death-kidney-dialysis.html Diseases, Conditions, Syndromes Fri, 12 Oct 2012 04:49:33 EST news269236161 Concussions and even lesser head impacts may speed up the brain's natural aging process by causing signaling pathways in the brain to break down more quickly than they would in someone who has never suffered a brain injury or concussion. http://medicalxpress.com/news/2012-07-concussions-impacts-brain-aging.html Neuroscience Tue, 31 Jul 2012 15:01:42 EST news262965696 A new study finds that a drop in testosterone levels over time is more likely to result from a man's behavioral and health changes than by aging. The study results will be presented Monday at The Endocrine Society's 94th Annual Meeting in Houston. http://medicalxpress.com/news/2012-06-declining-testosterone-men-aging.html Health Sat, 23 Jun 2012 13:10:01 EST news259674737 It is well-known that the risks of breast cancer increase dramatically for women over the age of 50, but what takes place at the cellular level to cause this increase has been a mystery. Some answers and the possibility of preventative measures in the future are provided in a new study by researchers at the DOE's Lawrence Berkeley National Laboratory (Berkeley Lab). http://medicalxpress.com/news/2012-06-aging-breast-cancer-uncover-cellular.html Cancer Mon, 04 Jun 2012 11:57:12 EST news258029819 Efforts to understand how the aging process affects the brain and cognition have expanded beyond simply comparing younger and older adults. http://medicalxpress.com/news/2012-05-wsu-genes-vascular-effects-aging.html Neuroscience Wed, 09 May 2012 17:32:07 EST news255803469 (Medical Xpress) -- Researchers from several institutions in the Philadelphia area have banded together to form a team to look into the possible impact a certain type of MicroRNA (miRNA) may have on the neurological aging process in fruit flies. They have, as they report in their paper published in Nature, found that when the miRNA, miR-34 is more active, neuron degradation due to aging is less pronounced than when it is less so or absent. http://medicalxpress.com/news/2012-02-link-microrna-neurological-aging-fruit.html Medical research Thu, 16 Feb 2012 08:30:04 EST news248601098 Henry Ford Hospital researchers have identified for the first time two molecules that hold promise as a biomarker for measuring cartilage damage associated with osteoarthritis. http://medicalxpress.com/news/2012-02-identity-potential-biomarker-osteoarthritis.html Arthritis & Rheumatism Sun, 05 Feb 2012 05:36:53 EST news247642591 Having diabetes may cause women to experience a greater degree of hearing loss as they age, especially if the metabolic disorder is not well controlled with medication, according to a new study from Henry Ford Hospital in Detroit. http://medicalxpress.com/news/2012-01-diabetes-affects-loss-women.html Diabetes Thu, 26 Jan 2012 09:57:06 EST news246794210 Mice bred to age too quickly seemed to have sipped from the fountain of youth after scientists at the University of Pittsburgh School of Medicine injected them with stem cell-like progenitor cells derived from the muscle of young, healthy animals. Instead of becoming infirm and dying early as untreated mice did, animals that got the stem/progenitor cells improved their health and lived two to three times longer than expected, according to findings published in the Jan. 3 edition of Nature Communications. http://medicalxpress.com/news/2012-01-shot-young-stem-cells-rapidly.html Medical research Tue, 03 Jan 2012 11:22:17 EST news244812128 Human stem cells aren't immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that comprise the blood and immune system. Understanding when and how these stem cells begin to falter as the years pass may explain why some diseases, such as acute myeloid leukemia, increase in prevalence with age, and also why elderly people tend to be more vulnerable to infections such as colds and the flu. http://medicalxpress.com/news/2011-11-aging-stem-cells-higher-prevalence.html Medical research Mon, 28 Nov 2011 15:00:06 EST news241713853 After men become fathers for the first time, they show significant decreases in crime, tobacco and alcohol use, according to a new, 19-year study. http://medicalxpress.com/news/2011-11-fatherhood-bad-habits.html Health Mon, 07 Nov 2011 12:48:07 EST news239892478 Researchers have shown they can reverse the aging process for human adult stem cells, which are responsible for helping old or damaged tissues regenerate. The findings could lead to medical treatments that may repair a host of ailments that occur because of tissue damage as people age. A research group led by the Buck Institute for Research on Aging and the Georgia Institute of Technology conducted the study in cell culture, which appears in the September 1, 2011 edition of the journal Cell Cycle. http://medicalxpress.com/news/2011-09-scientists-clock-adult-stem-cells.html Medical research Tue, 20 Sep 2011 15:46:00 EST news235752345 Loss of muscle mass is not only associated with disease, such as HIV and cancer, but also with the normal aging process. Anabolic steroids are sometimes used to reverse loss of lean muscle tissue but they can have unwanted side effects. New research, published in BioMed Central's open access journal Immunity and Aging, shows that nine proteins, isolated from blood, alter with age and that the profile of some of these proteins can be reversed by testosterone treatment. http://medicalxpress.com/news/2011-06-proteins-aging.html Medical research Sun, 19 Jun 2011 20:00:03 EST news227707608 (Medical Xpress) -- In a new study, Yale University researchers have identified a pathway by which reactive oxygen species (ROS) molecules, which are usually implicated in the aging process due to their damage to DNA, can also act as cellular signaling molecules that extend lifespan. The study, which provides insights into the underlying mechanisms of the ROS signaling process, is published in the June issue of Cell Metabolism. http://medicalxpress.com/news/2011-06-blamed-aging-ros-molecules-life.html Medical research Wed, 08 Jun 2011 05:16:41 EST news226728970 A new research report appearing online in the FASEB Journal shows that what someone drinks after exercise plays a critical role in maximizing the effects of exercise. Specifically, the report shows that protein drinks after aerobic activity increases the training effect after six weeks, when compared to carbohydrate drinks. Additionally, this study suggests that this effect can be seen using as little as 20 grams of protein. http://medicalxpress.com/news/2011-05-protein-aging-muscles.html Health Wed, 25 May 2011 16:15:59 EST news225558943