http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain access to oxygen and nutrients, necessitating an expansion of the cardiac vasculature. http://medicalxpress.com/news/2013-03-response-cardiac-stress.html Cardiology Fri, 01 Mar 2013 12:16:43 EST news281362596 Pancreatic cancer is a deadly disease with increased incidences in the recent years. According to NDSU researchers, epidemiological data show chronic stress in a negative social and psychological state such as depression might serve as a risk factor for cancer development and progression. However, the underlying biological mechanisms are not well understood.  http://medicalxpress.com/news/2013-02-link-stress-pancreatic-cancer-paper.html Cancer Fri, 15 Feb 2013 10:40:02 EST news280143750 Korean researchers believe that the 'DJ-1 protein' can be used to promote the formation of new bone tissue in patients suffering from osteoporosis by improving communication between bone making cells (osteoblasts) and blood vessel (endothelial) cells. The research was published in Nature Communications. http://medicalxpress.com/news/2013-01-uncovers-protein-bones.html Medical research Thu, 10 Jan 2013 06:27:44 EST news277021658 An Inserm team in Dijon directed by François Ghiringhelli is to publish an article this week in the Nature Medicine review. The article suggests that two chemotherapy drugs frequently used to treat digestive and breast cancers may encourage the development of tumors by modulating the anti-tumoral immune response. http://medicalxpress.com/news/2012-12-chemotherapy-effectiveness-immune.html Immunology Tue, 04 Dec 2012 13:02:28 EST news273848532 Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, Massachusetts General Hospital (MGH) investigators report the first preclinical study combining antiangiogenic and anti-HER2 drugs in an animal model of brain metastatic breast cancer. http://medicalxpress.com/news/2012-11-combination-treatment-survival-breast-cancer.html Cancer Thu, 01 Nov 2012 16:56:02 EST news271007751 There are many factors that affect tumor invasion, the process where a tumor grows beyond the tissue where it first developed. While factors like genetics, tissue type and environmental exposure affect tumor metastasis and invasion, physical forces like fluid flow remain a poorly understood component of tumor invasion. http://medicalxpress.com/news/2012-07-fluid-cells-affects-tumors.html Cancer Wed, 25 Jul 2012 12:36:51 EST news262438606 Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step in understanding the molecular mechanisms of liver cancer progression and could lead to novel therapies for the disease. http://medicalxpress.com/news/2012-07-scientists-mouse-therapies-liver-cancer.html Cancer Fri, 06 Jul 2012 18:46:54 EST news260819209 (Medical Xpress) -- Stem cells often used in reconstructive surgery following mastectomies and other cancer-removal treatments may pose a danger: Cornell biomedical scientists have discovered that these cells, in contact with even trace amounts of cancer cells, can create a microenvironment suitable for more tumors to grow. http://medicalxpress.com/news/2012-06-stem-cells-trigger-tumors.html Cancer Tue, 05 Jun 2012 05:46:10 EST news258093894 Apigenin, a natural substance found in grocery store produce aisles, shows promise as a non-toxic treatment for an aggressive form of human breast cancer, following a new study at the University of Missouri. MU researchers found apigenin shrank a type of breast cancer tumor that is stimulated by progestin, a synthetic hormone given to women to ease symptoms related to menopause. http://medicalxpress.com/news/2012-05-breast-cancer-effectively-chemical-celery.html Cancer Wed, 16 May 2012 09:20:14 EST news256378808 Scientists from the MIRA and MESA+ research institutes at the University of Twente (The Netherlands) have discovered an ‘on/off switch’ for angiogenesis in human tissue. Their research has shown that the growth of new blood vessels can be controlled by using mechanical forces in cells. This discovery is an important step towards making the cultivation of new tissue, or even organs, possible. The researchers recently published their results in the leading scientific journal PNAS. http://medicalxpress.com/news/2012-04-on-off-angiogenesis.html Medical research Fri, 27 Apr 2012 07:52:34 EST news254731943 Researchers have combined bioactive peptides to successfully stimulate wound healing. The in vitro and in vivo study, published today in PLoS ONE, demonstrates that the combination of two peptides stimulates the growth of blood vessels and promotes re-growth of tissue. Further development of these peptides could lead to a new treatment for chronic and acute wounds. http://medicalxpress.com/news/2012-02-bioactive-peptides-wound-vivo.html Medical research Fri, 24 Feb 2012 09:55:53 EST news249299746 New research explains how cells regulate their bonds during the development of new blood vessels. For the first time, the role of the protein Raf-1 in determining the strength of the bond between cells has been shown. If Raf-1 is not present, the cells cannot stick together and the formation of new blood vessels is inhibited. This discovery may one day lead to new approaches to cancer treatment. http://medicalxpress.com/news/2012-01-essential-protein-formation-blood-vessels.html Medical research Tue, 17 Jan 2012 07:40:01 EST news246007679 Researchers at the Swedish medical university Karolinska Institutet have demonstrated that a growth hormone, PDGF-BB, and the blood protein EPO are involved in the development of cancer tumours and that they combine to help the tumours proliferate in the body. These new preclinical findings offer new potential for inhibiting tumour growth and bypassing problems of resistance that exist with many drugs in current use. The results are published in the scientific journal Nature Medicine. http://medicalxpress.com/news/2011-12-blood-protein-epo-involved-cancer.html Cancer Mon, 05 Dec 2011 11:20:54 EST news242306441 Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, held Nov. 12-16, 2011. http://medicalxpress.com/news/2011-11-combination-therapy-potent-tumor-growth.html Cancer Sun, 13 Nov 2011 14:14:57 EST news240416091 A new and better understanding of blood vessel growth and vascular development (angiogenesis) in cancer has been made possible by research carried out by a team of scientists from Moffitt Cancer Center, the University of Florida, Harvard University, Yale University and the Children's Hospital of Los Angeles. http://medicalxpress.com/news/2011-09-scientists-key-molecule-blocks-abnormal.html Medical research Wed, 21 Sep 2011 13:43:55 EST news235831424 A team of researchers from Spain and Switzerland have developed a new model for studying the development of testicular germ cell tumors by transplanting embryonic stem cells into the seminiferous tubules in mouse models, resulting in the development of testicular germ cell tumors (TGCT) that mimic the early stages of TGCT development. The study, published in Cell Transplantation (20:5), is now freely available on-line. http://medicalxpress.com/news/2011-07-germ-cell-tumors-embryonic-stem.html Cancer Mon, 11 Jul 2011 12:14:41 EST news229605253 Scientists identify in the journal Nature a new molecular pathway used to suppress blood vessel branching in the developing retina – a finding with potential therapeutic value for fighting diseases of the retina and a variety of cancers. http://medicalxpress.com/news/2011-05-molecular-pathway-angiogenesis-retinal-disease.html Medical research Sun, 29 May 2011 13:00:18 EST news225887427 Parsley is usually used as a decorative accent to a scrumptious meal, but don't set it aside just yet. In a new study, a University of Missouri researcher has found that a compound in parsley and other plant products, including fruits and nuts, can stop certain breast cancer tumor cells from multiplying and growing. The study was published recently in Cancer Prevention Research. http://medicalxpress.com/news/2011-05-parsley-celery-crucial-component-breast.html Cancer Mon, 09 May 2011 12:30:30 EST news224162997