http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published in the print edition of the journal Human Molecular Genetics. The research indicates that these genetic changes come in the form of an excess of duplicated DNA segments in hotspot regions and may affect the chances that a child will develop autism—a behavioral disorder that affects about 1 of every 88 children in the United States, according to the Centers for Disease Control. http://medicalxpress.com/news/2013-04-autism-linked-genetic-regions-genome.html Autism spectrum disorders Wed, 03 Apr 2013 09:59:49 EST news284201977 After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked the disease's reemergence to specific genetic anomalies. http://medicalxpress.com/news/2013-02-mutations-linked-relapse-childhood-leukemia.html Genetics Sun, 03 Feb 2013 13:00:04 EST news279114848 Mutations in single genes can cause catastrophic diseases, such as Huntington's Disease or sickle cell anemia. However, many conditions, including cancer, diabetes and birth defects are multigenic, arising from the collective failure of the function of more than one gene. http://medicalxpress.com/news/2013-01-deficiencies-genes-synergize-halt-formation.html Genetics Thu, 31 Jan 2013 10:51:08 EST news278851794 Researchers from Inserm and the Université Lille/Université Lille Nord de France have recently used a neurodegeneration model of Alzheimer's disease to provide experimental evidence of the relationship between obesity and disorders linked to the tau protein. This research was conducted on mice and is published in the Diabetes Review. It corroborates the theory that metabolic anomalies contribute massively to the development of dementia. http://medicalxpress.com/news/2013-01-detrimental-effect-obesity-lesions-alzheimer.html Alzheimer's disease & dementia Mon, 07 Jan 2013 12:30:41 EST news276784231 (HealthDay)—Improved understanding of the pathogenesis of infantile hemangiomas (IHs) is leading to better treatment options, according to a review published online Dec. 24 in Pediatrics. http://medicalxpress.com/news/2012-12-infantile-hemangiomas.html Pediatrics Thu, 27 Dec 2012 15:00:01 EST news275838784 Far from processing every word we read or hear, our brains often do not even notice key words that can change the whole meaning of a sentence, according to new research from the Economic and Social Research Council (ESRC). http://medicalxpress.com/news/2012-07-message.html Psychology & Psychiatry Mon, 16 Jul 2012 09:56:34 EST news261651381 Noah Jackson was born without a voice. Because of a rare genetic disease, his airway was so narrow he couldn't cry at birth. In fact, he could scarcely breathe, and had surgery when he was 5 days old to implant a tracheostomy tube that let air pass through a hole in his throat. Cuddling their newborn, parents KC and Rebecca knew Noah's only hope for someday speaking and breathing normally lay in the possibility that his voice box could be surgically reconstructed later on. http://medicalxpress.com/news/2012-07-surgery-packard-children-boy-airway.html Surgery Mon, 16 Jul 2012 09:47:19 EST news261650818 (HealthDay) -- Sperm with higher motility have increased mitochondrial respiratory capacity, according to a study published in the April issue of Urology. http://medicalxpress.com/news/2012-04-mitochondrial-respiratory-capacity-sperm-motility.html Other Tue, 10 Apr 2012 15:40:01 EST news253286549 Armed with a new ability to find retinal anomalies at the cellular level, neurobiologists at St. Jude Children's Research Hospital have made a discovery they hope will ultimately lead to a treatment for cancer of the retina. http://medicalxpress.com/news/2011-12-ornl-image-analysis-prowess-advances.html Medical research Wed, 21 Dec 2011 16:47:21 EST news243708428 Using magnetic resonance imaging (MRI) and nanoparticle technology, researchers from Yale have devised a way to monitor the growth of laboratory-engineered blood vessels after they have been implanted in patients. This advance represents an important step toward ensuring that blood vessels, and possibly other tissues engineered from a patient's own biological material, are taking hold and working as expected. Until now, there has been no way to monitor the growth and progress of engineered tissues once they were implanted. This research was published in the December 2011 issue of the FASEB Journal. http://medicalxpress.com/news/2011-11-blood-vessels-patients.html Medical research Wed, 30 Nov 2011 13:14:23 EST news241881255 Swiss technological university EPFL said Tuesday it created an electronic system that detects cardiac problems instantly and passes on the data through a mobile phone to medical personnel. http://medicalxpress.com/news/2011-10-swiss-university-cardiac-issues-detector.html Cardiology Tue, 18 Oct 2011 09:54:15 EST news238150425 Researchers have described a new, recessively inherited human syndrome featuring craniosynostosis, maxillary hyperplasia, delayed tooth eruption and extra teeth. They also identified causative mutations in a gene IL11RA. http://medicalxpress.com/news/2011-07-craniosynostosis-tooth-eruption-supernumerary-teeth.html Medical research Thu, 07 Jul 2011 12:44:57 EST news229261478 A clinically extensive and mathematically powerful study of 1000 families with one autistic child and one unaffected sibling has validated a controversial theory of autism's complex genetic causation. The study for the first time estimates the minimum number of locations in the human genome -- 250 to 300 -- where gene copy number variation (CNV) can give rise to autism spectrum disorder (ASD). It also sheds new light on the long observed but little understood "gender bias" of autism, an illness that typically manifests by age 3 and affects about four times more boys than girls. http://medicalxpress.com/news/2011-06-autism-validates-importance-spontaneous-causal.html Genetics Wed, 08 Jun 2011 13:11:23 EST news226757464