http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (HealthDay)—Antibiograms, which are designed to help physicians select appropriate antimicrobials to treat bacterial pathogens, should be specifically tailored for outpatients in primary care settings, according to research published in the May issue of Diagnostic Microbiology & Infectious Disease. http://medicalxpress.com/news/2013-05-specific-antibiograms-outpatients-primary.html Diseases, Conditions, Syndromes Sat, 11 May 2013 04:30:01 EST news287461067 A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs). http://medicalxpress.com/news/2013-03-utis-flagellin-key-body-natural.html Medical research Fri, 15 Mar 2013 03:00:04 EST news282499121 Antibiotic resistance "has the potential to undermine modern health systems," argue health economists Richard Smith and Joanna Coast on bmj.com today. They believe that an increase in resistant organisms coupled with a big fall in the number of new antimicrobial drugs "suggests an apocalyptic scenario may be looming." http://medicalxpress.com/news/2013-03-antibiotic-resistance-potential-undermine-modern.html Diseases, Conditions, Syndromes Mon, 11 Mar 2013 12:59:09 EST news282225543 Treatment with a newer antibiotic, tedizolid phosphate, once daily for 6 days was statistically noninferior (no worse than) in efficacy to the antibiotic linezolid twice daily for 10 days for both early (at day 2 to 3) and sustained (at day 11) clinical responses in patients with acute bacterial skin and skin structure infections, according to a study appearing in the February 13 issue of JAMA. http://medicalxpress.com/news/2013-02-shorter-course-antibiotic-similar-effectiveness-skin.html Diseases, Conditions, Syndromes Tue, 12 Feb 2013 16:30:02 EST news279906626 Nisin, a common food preservative, may slow or stop squamous cell head and neck cancers, a University of Michigan study found. http://medicalxpress.com/news/2012-10-common-food-tumor-growth.html Cancer Wed, 31 Oct 2012 19:10:13 EST news270929405 Microbial infections are becoming unbeatable due to progressive mutations that lead to antimicrobial drug resistance. European scientists exploited the characteristics of novel antimicrobial compounds that mimic the dual activities of natural antimicrobial proteins. http://medicalxpress.com/news/2012-08-immune-antimicrobials.html Medications Thu, 30 Aug 2012 09:24:29 EST news265537460 Many people have probably heard of off-label drug use, but they may not know when that applies to prescriptions they are taking, a Mayo Clinic analysis found. Off-label drug use occurs when a physician prescribes medication to treat a condition before that use has been approved by the Food and Drug Administration. In a newly published article in Mayo Clinic Proceedings, researchers pose and answer 10 questions about off-label drug use. http://medicalxpress.com/news/2012-08-off-label-drug-common-patients-theyre.html Medications Mon, 06 Aug 2012 12:04:10 EST news263473443 A 14-year-old Texas girl was finally cured of an oft-fatal emerging disease when doctors amputated her lower leg, where the infection arose, after various antimicrobials proved ineffective. The culprit was Pythium insidiosum, a fungus-like microbe which rarely causes disease in humans and then primarily in Thailand. The case “clearly highlights the need for clinicians to have the best support possible from the clinical microbiology lab,” says Don Murphey of Cook Children’s Medical Center, who served as attending physician during the case. The case report is published in the April Journal of Clinical Microbiology. http://medicalxpress.com/news/2012-04-rare-emerging-disease-texas-girls.html Diseases, Conditions, Syndromes Tue, 17 Apr 2012 09:30:06 EST news253872978 Infection preventionists and healthcare epidemiologists play key roles in promoting effective antimicrobial stewardship in collaboration with other health professionals, according to a joint position paper published today by the Association for Professionals in Infection Control and Epidemiology (APIC) and the Society for Healthcare Epidemiology of America (SHEA) in their respective peer-review journals, the American Journal of Infection Control and Infection Control and Hospital Epidemiology. http://medicalxpress.com/news/2012-03-infection-groups-outline-antibiotics.html Diseases, Conditions, Syndromes Mon, 19 Mar 2012 11:44:51 EST news251376282 Curbing unnecessary use of antibiotics is our best defense against the spread of drug-resistant infections. A new study suggests another benefit to antimicrobial stewardship: a potential cost savings of millions of dollars now wasted on therapies that don't help patients. http://medicalxpress.com/news/2012-03-antibiotic-millions.html Diseases, Conditions, Syndromes Thu, 15 Mar 2012 05:14:09 EST news251007206 Ongoing research at the Institute of Food Research, which is strategically funded by BBSRC, is exploring the use of virus-produced proteins that destroy bacterial cells to combat potentially dangerous microbial infections. Bacteriophages produce endolysin proteins that specifically target certain bacteria, and IFR has been studying one that destroys Clostridium difficile, a common and dangerous source of hospital-acquired infections. New research is showing that it is possible to 'tune' these endolysin properties to increase their effectiveness and aid their development as a new weapon in the battle against superbugs. http://medicalxpress.com/news/2011-08-tuning-natural-antimicrobials-effectiveness-superbugs.html Diseases, Conditions, Syndromes Mon, 22 Aug 2011 12:12:34 EST news233233927 Excessive use of antimicrobials in livestock promotes resistance and risks the future health of both animals and humans, warn experts in an editorial published by Student BMJ today. http://medicalxpress.com/news/2011-06-overuse-antimicrobials-livestock-human-health.html Diseases, Conditions, Syndromes Thu, 02 Jun 2011 06:40:27 EST news226215614