http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Depression in a group of Medicare recipients ages 65 years and older appears to be associated with prevalent mild cognitive impairment and an increased risk of dementia, according to a report published Online First by Archives of Neurology, a JAMA Network publication. http://medicalxpress.com/news/2012-12-late-life-depression-prevalent-mild-cognitive.html Neuroscience Mon, 31 Dec 2012 16:00:04 EST news276174351 (HealthDay)—In-office eye scans that assess the thinning of the retina may also help doctors determine how fast multiple sclerosis (MS) is progressing in patients with the nervous system disease, a new study suggests. http://medicalxpress.com/news/2012-12-eye-scan-track-multiple-sclerosis.html Neuroscience Mon, 24 Dec 2012 18:07:39 EST news275594846 A new imaging technique developed at MIT offers the first glimpse of the degeneration of two brain structures affected by Parkinson's disease. http://medicalxpress.com/news/2012-11-scientists-image-brain-deteriorate-parkinson.html Neuroscience Mon, 26 Nov 2012 16:26:17 EST news273169560 (HealthDay)—In patients with acute ischemic stroke, aspirin resistance is associated with increased stroke severity and infarct size, according to research published online Nov. 19 in the Archives of Neurology. http://medicalxpress.com/news/2012-11-aspirin-resistance-ups-severity-acute.html Cardiology Wed, 21 Nov 2012 15:10:01 EST news272728841 Physical exercise, including treadmill, stretching and resistance exercises, appears to improve gait speed, muscle strength and fitness for patients with Parkinson disease (PD), according to a report of a randomized clinical trial published Online First by Archives of Neurology, a JAMA Network publication. http://medicalxpress.com/news/2012-11-physical-gait-muscle-strength-patients.html Parkinson's & Movement disorders Mon, 05 Nov 2012 16:00:06 EST news271337584 (HealthDay)—Although safe and well tolerated, the experimental small molecule latrepirdine does not improve cognition after six months of treatment in patients with mild-to-moderate Huntington's disease (HD), according to a study published online Oct. 29 in the Archives of Neurology. http://medicalxpress.com/news/2012-11-latrepirdine-effective-huntington-disease.html Neuroscience Thu, 01 Nov 2012 19:40:01 EST news271013882 Poor physical performance on activities including walking was associated with increased odds of dementia in a study of individuals 90 years and older, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2012-10-patients-ages-older-links-poor.html Neuroscience Mon, 22 Oct 2012 16:00:11 EST news270137022 A medical record review study of 97 patients with the fatal, degenerative brain disorder sporadic Jakob-Creutzfeldt disease (sCJD) suggests that a correct diagnosis of the disease was often delayed by a variety of misdiagnoses, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2012-09-misdiagnosis-sporadic-jakob-creutzfeldt-disease.html Neuroscience Mon, 24 Sep 2012 16:00:07 EST news267704801 (HealthDay)—In autopsy findings, patients treated with angiotensin receptor blockers (ARBs) show less Alzheimer's disease (AD)-related pathology, according to a study published online Sept. 10 in the Archives of Neurology. http://medicalxpress.com/news/2012-09-alzheimer-pathology-angiotensin-receptor-blocker.html Alzheimer's disease & dementia Wed, 12 Sep 2012 11:30:03 EST news266666081 (HealthDay)—Levels of five different cerebrospinal fluid (CSF) biomarkers are able to improve differentiation between common dementia and parkinsonian disorders, according to a study published online Aug. 27 in the Archives of Neurology. http://medicalxpress.com/news/2012-08-csf-markers-differentiate-dementia-parkinsonism.html Neuroscience Tue, 28 Aug 2012 12:50:01 EST news265375345 (HealthDay) -- Shortened telomere length (TL) is associated with risks for dementia and mortality in a population of older adults, according to a study published online July 23 in the Archives of Neurology. http://medicalxpress.com/news/2012-07-shortened-telomere-length-tied-dementia.html Neuroscience Wed, 25 Jul 2012 13:30:01 EST news262439857 Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust. http://medicalxpress.com/news/2012-07-strong-brain-muscle-requires-protein.html Neuroscience Wed, 11 Jul 2012 12:44:05 EST news261229404 The medication fingolimod reduced inflammatory lesion activity and reduced brain volume loss in patients with multiple sclerosis who participated in a two-year placebo-controlled clinical trial and were assessed by magnetic resonance imaging (MRI) measures, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2012-07-fingolimod-therapy-patients-multiple-sclerosis.html Neuroscience Mon, 02 Jul 2012 16:00:03 EST news260456972 Among well-functioning older adults without dementia, diabetes mellitus (DM) and poor glucose control among those with DM are associated with worse cognitive function and greater cognitive decline, according to a report published Online First by Archives of Neurology, a JAMA Network publication. http://medicalxpress.com/news/2012-06-diabetes-poor-glucose-greater-cognitive.html Neuroscience Mon, 18 Jun 2012 16:00:18 EST news259250436 A study on a handful of people with suspected mild Alzheimer's disease (AD) suggests that a device that sends continuous electrical impulses to specific "memory" regions of the brain appears to increase neuronal activity. Results of the study using deep brain stimulation, a therapy already used in some patients with Parkinson's disease and depression, may offer hope for at least some with AD, an intractable disease with no cure. http://medicalxpress.com/news/2012-05-deep-brain-mild-alzheimer-disease.html Neuroscience Mon, 07 May 2012 16:00:17 EST news255615020 According to a new study, the neuron-killing pathology of Alzheimer's disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau. http://medicalxpress.com/news/2012-04-clinical-decline-alzheimer-requires-plaque.html Neuroscience Mon, 23 Apr 2012 16:00:10 EST news254397715 Persistent ocular tremors that prevent eye stability during fixation appear to be common among patients with Parkinson disease (PD) suggesting that precise oculomotor testing could provide an early physiological biomarker for diagnosing PD, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2012-04-persistent-ocular-tremors-parkinson-disease.html Parkinson's & Movement disorders Mon, 09 Apr 2012 16:00:01 EST news253189649 Immunotherapy with the antibody bapineuzumab in patients with mild to moderate Alzheimer disease resulted in decreases in a cerebrospinal fluid biomarker, which may indicate downstream effects on the degenerative process, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2012-04-immunotherapy-cerebrospinal-fluid-biomarkers-patients.html Alzheimer's disease & dementia Mon, 02 Apr 2012 16:00:06 EST news252590312 A meta-analysis of previously published studies found that the ratio of blood plasma amyloid-β (Aβ) peptides Aβ42:Aβ40 was significantly associated with development of Alzheimer disease and dementia, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2012-03-link-blood-biomarkers-alzheimer-disease.html Neuroscience Mon, 26 Mar 2012 16:00:14 EST news251985816 (Medical Xpress) -- Knowledge of a disease prevalent among Northern Territory Indigenous communities has been overhauled thanks to research contributed by the University of Sydney's Garth Nicholson. http://medicalxpress.com/news/2012-03-asian-machado-joseph-disease-revealed.html Diseases, Conditions, Syndromes Fri, 09 Mar 2012 06:50:01 EST news250497215 Cognitive loss and brain degeneration currently affect millions of adults, and the number will increase, given the population of aging baby boomers. Today, nearly 20 percent of people age 65 or older suffer from mild cognitive impairment and 10 percent have dementia. http://medicalxpress.com/news/2012-02-brain-imaging-technique-cognitive-decline.html Neuroscience Mon, 13 Feb 2012 16:00:05 EST news248370873 Many patients currently diagnosed with very mild or mild Alzheimer disease dementia could potentially be reclassified as having mild cognitive impairment (MCI) under revised criteria for that condition, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2012-02-criteria-reclassify-mild-alzheimer-dementia.html Alzheimer's disease & dementia Mon, 06 Feb 2012 16:00:06 EST news247756138 A sedentary lifestyle is associated with greater cerebral amyloid deposition, which is characteristic of Alzheimer’s disease (AD), among cognitively normal individuals with the ε4 allele of the apolipoprotein E (APOE) gene, according to a report published Online First by Archives of Neurology, one of the JAMA/Archives journals. http://medicalxpress.com/news/2012-01-lifestyle-alzheimer-disease-related-brain-persons.html Diseases, Conditions, Syndromes Mon, 16 Jan 2012 06:40:01 EST news245916858 Demographics and clinical factors appear to be associated with survival in patients with Parkinson disease (PD), and the presence of dementia is associated with a significant increase in mortality, according to a report in the January issue of Archives of Neurology. http://medicalxpress.com/news/2012-01-demographic-clinical-factors-survival-patients.html Parkinson's & Movement disorders Mon, 02 Jan 2012 16:00:04 EST news244731482 Following a major Northwestern Medicine breakthrough that identified a common converging point for all forms of amyotrophic lateral sclerosis (ALS and Lou Gehrig's disease), a new finding from the same scientists further broadens the understanding of why cells in the brain and spinal cord degenerate in the fatal disease. http://medicalxpress.com/news/2011-11-bad-gene-linked-cell-buildup.html Genetics Mon, 21 Nov 2011 16:20:19 EST news241114788 Although it is a small study and more clinical trials are needed, treatment with the medication gantenerumab appeared to result in a reduction in brain amyloid levels in patients with Alzheimer disease, according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2011-10-small-association-medication-reduction-brain.html Neuroscience Mon, 10 Oct 2011 16:00:11 EST news237468335 A marker for Alzheimer's disease rises and falls in the spinal fluid in a daily pattern that echoes the sleep cycle, researchers at Washington University School of Medicine in St. Louis have found. http://medicalxpress.com/news/2011-09-marker-alzheimer-disease-day-falls.html Alzheimer's disease & dementia Mon, 26 Sep 2011 16:22:03 EST news236272899 Among patients who have had an ischemic stroke, use of cholesterol-lowering statin medications is not associated with subsequent intracerebral hemorrhage (bleeding in the brain), according to a report published Online First by Archives of Neurology. http://medicalxpress.com/news/2011-09-link-intracerebral-hemorrhage-statin-patients.html Neuroscience Mon, 12 Sep 2011 16:51:06 EST news235065048 Intranasal insulin therapy appears to provide some benefit for cognitive function in patients with amnestic mild cognitive impairment and Alzheimer disease, according to a report published Online First today by Archives of Neurology. http://medicalxpress.com/news/2011-09-intranasal-insulin-therapy-adults-mild.html Neuroscience Mon, 12 Sep 2011 16:49:53 EST news235064405 One decade after receiving implants that stimulate areas of their brains, patients with Parkinson's disease (PD) appear to sustain improvement in motor function, although part of the initial benefit wore off mainly because of progressive loss of benefit in other functions, according to a report published Online First by Archives of Neurology, one of the JAMA/Archives journals. http://medicalxpress.com/news/2011-08-deep-brain-effects-years-patients.html Neuroscience Mon, 08 Aug 2011 16:20:01 EST news232031065