http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (HealthDay)—People who have type 1 diabetes are more likely than others to develop an autoimmune thyroid condition. http://medicalxpress.com/news/2013-03-people-diabetes-thyroid-disease.html Diabetes Fri, 15 Mar 2013 13:03:59 EST news282571430 In type 1 diabetes, the immune system destroys insulin-producing cells in the pancreas, but the precise cause has not been clear. A study published by Cell Press on March 5th in Cell Metabolism reveals that a single mutation in the "longevity gene" SIRT1 can cause type 1 diabetes in humans. The findings unearth the role this gene plays in human autoimmunity and disease and also offer new avenues for treating a range of autoimmune disorders. http://medicalxpress.com/news/2013-03-discovery-human-genetic-mutation-treatments.html Genetics Tue, 05 Mar 2013 12:00:05 EST news281706639 Regular exposure to sunlight—specifically ultraviolet B (UVB)—may reduce the risk of developing rheumatoid arthritis, indicates a large long term study published online in the Annals of the Rheumatic Diseases. http://medicalxpress.com/news/2013-02-sunlight-ward-rheumatoid-arthritis-women.html Arthritis & Rheumatism Mon, 04 Feb 2013 18:30:05 EST news279198648 A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The findings suggest that blocking this pathway in lupus-triggering cells could be a potent weapon against the disease. http://medicalxpress.com/news/2013-02-scientists-key-element-lupus-drug.html Medical research Mon, 04 Feb 2013 17:43:05 EST news279222177 B cells can generate different 'classes' of antibodies, each of which carries a specific type of protein chain that triggers a specific downstream cascade of immune responses. Immunoglobulin M (IgM) antibodies, which are the first on the scene, play a particularly important role in fighting off pathogen infection. http://medicalxpress.com/news/2013-02-receptor-trigger-immune-response.html Immunology Fri, 01 Feb 2013 10:17:17 EST news278936230 When a virus such as influenza invades our bodies, interferon proteins are among the first immune molecules produced to fight off the attack. Interferon can also play a role in suppressing tumor growth and the effects of autoimmune diseases, and doctors may use an artificial form of interferon to treat patients with certain cancers or multiple sclerosis. But even this approach sometimes fails when patients' bodies reject the foreign interferon or growing resistant to its effects. http://medicalxpress.com/news/2012-11-medicine-approach-combat-viral-infections.html Medical research Fri, 09 Nov 2012 16:32:43 EST news271701151 Scientists affiliated with VIB and UGent have discovered a mechanism used by the protein A20 to combat inflammation. This could be a very important point of focus in the search for a treatment for autoimmune diseases such as Rheumatoid Arthritis, in which the patient suffers from chronic, uncontrolled inflammation. http://medicalxpress.com/news/2012-10-focus-treatment-rheumatoid-arthritis-autoimmune.html Arthritis & Rheumatism Tue, 09 Oct 2012 11:07:42 EST news268999655 Researchers at the Walter and Eliza Hall Institute have discovered that a pair of molecules work together to kill so-called 'self-reactive' immune cells that are programmed to attack the body's own organs. The finding is helping to explain how autoimmune diseases develop. http://medicalxpress.com/news/2012-09-immune-cell-death-safeguards-autoimmune.html Immunology Thu, 06 Sep 2012 12:00:05 EST news266148082 (Medical Xpress) -- A large, RIKEN-led, international team of genome researchers has found nine new associations of gene regions or loci with the autoimmune disease rheumatoid arthritis. The loci, found in ethnically Japanese populations, had been undetected in previous European studies. Three of the loci are also associated with other autoimmune conditions in the Japanese, one with systemic lupus and two with Graves’ disease. http://medicalxpress.com/news/2012-08-arthritis.html Genetics Fri, 17 Aug 2012 08:37:40 EST news264411438 Researchers at Mount Sinai School of Medicine in New York have found new clues in the pathogenesis of skull and skin birth defects associated with a rare genetic disorder, Beare-Stevenson cutis gyrata syndrome (BSS). Using a mouse model, investigators found that by inhibiting the protein p38, previously associated with cancer and certain autoimmune conditions, they were able to interrupt development of specific birth defects associated with it: craniosynostosis, or the premature fusion of certain bones of the skull, and acanthosis nigricans, a hyperpigmentation skin disorder that often makes the skin look dirty and rough. http://medicalxpress.com/news/2012-05-protein-inhibitor-potential-medical-treatments.html Pediatrics Tue, 15 May 2012 12:00:07 EST news256299828 In the limited time of an office visit, how can a primary care physician make the case to parents that their child should be vaccinated? During National Infant Immunization Week, a Mayo Clinic vaccine expert and a pediatrician offer suggestions for refuting three of the most common myths about child vaccine safety. Their article, The Clinician's Guide to the Anti-Vaccinationists' Galaxy, is published online this month in the journal Human Immunology. http://medicalxpress.com/news/2012-04-physician-anti-vaccine-parents.html Immunology Mon, 23 Apr 2012 17:11:34 EST news254419883 Gardasil, the human papillomavirus vaccine that is now recommended for male and female adolescents and young adults, does not trigger autoimmune conditions such as lupus, rheumatoid arthritis, type 1 diabetes or multiple sclerosis after vaccination in young women, according to a new study in the Journal of Internal Medicine. http://medicalxpress.com/news/2012-01-gardasil-trigger-autoimmune-conditions-vaccination.html Immunology Wed, 25 Jan 2012 09:29:21 EST news246706145 Vitamin D levels are significantly lower in patients with recurrent inflammatory spinal cord disease, according to a study published Online First by Archives of Neurology. http://medicalxpress.com/news/2011-11-vitamin-d-recurrent-inflammatory-spinal.html Neuroscience Mon, 14 Nov 2011 16:29:42 EST news240510574 Scientists at Mount Sinai Hospital, in collaboration with researchers at the University of Toronto, University Health Network and McGill University have obtained significant new insights into the causes of rheumatoid arthritis (RA) and other autoimmune disorders including type 1 diabetes, lupus and Graves disease. http://medicalxpress.com/news/2011-08-genetic-clue-rheumatoid-arthritis.html Genetics Sun, 14 Aug 2011 13:00:08 EST news232545414 The human body incorporates multiple fail-safe mechanisms to protect it against the "friendly fire" from its immune system known as autoimmune disease, Charis Teh and colleagues at the John Curtin School of Medical Research (JCSMR) at the Australian National University have found. http://medicalxpress.com/news/2011-07-multi-layered-armor-body-immune-failure.html Medical research Wed, 06 Jul 2011 13:45:52 EST news229178742 (Medical Xpress) -- Scientists at the University of Birmingham have discovered a 'molecular hoover' with the potential to prevent autoimmune conditions. http://medicalxpress.com/news/2011-05-scientists-immune.html Medical research Tue, 03 May 2011 15:10:01 EST news223652641