http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. HIV-positive patients have a higher incidence of non-melanoma skin cancers, according to a Kaiser Permanente study that appears in the current online issue of the Journal of the National Cancer Institute. Specifically, basal cell and squamous cell carcinomas occur more than twice as often among HIV-positive individuals compared to those who are HIV-negative. http://medicalxpress.com/news/2013-01-reveals-two-fold-higher-incidence-non-melanoma.html Cancer Tue, 29 Jan 2013 10:28:30 EST news278677701 Nearly the entire genetic landscape of the most common form of brain tumor can be explained by abnormalities in just five genes, an international team of researchers led by Yale School of Medicine scientists report online in the Jan. 24 edition of the journal Science. Knowledge of the genomic profile of the tumors and their location in the brain make it possible for the first time to develop personalized medical therapies for meningiomas, which currently are only managed surgically. http://medicalxpress.com/news/2013-01-genetic-landscape-common-brain-tumors.html Cancer Thu, 24 Jan 2013 14:00:23 EST news278257450 For years researchers have been trying to identify the molecular changes that occur in tumour-initiating cells from the very first oncogenic mutation to the development of invasive tumors. The most frequently diagnosed skin cancer in humans is basal cell carcinoma, with over a million such cases reported each year. An EU-funded team of researchers led by Prof. Cédric Blanpain of the Université libre de Bruxelles (ULB) has identified the molecular events that occur during basal cell carcinoma initiation. This study was recently published in the journal Nature Cell Biology and it was partially supported by the European Research Council (ERC) Starting Grant worth EUR 1.6 million awarded to Prof. Blanpain. http://medicalxpress.com/news/2012-12-scientists-uncover-cells-basal-cell.html Cancer Fri, 21 Dec 2012 06:36:54 EST news275294208 One of the most outstanding and unresolved questions in cancer biology is the identification of cells at the origin of cancer and the understanding of the molecular changes that occur in tumor initiating cells from the first oncogenic mutation to the development of invasive cancer. Basal cell carcinoma (BCC) is the most frequent cancer in human with more than million of new patients diagnosed each year with BCCs. Recently, the group of Pr. Cédric Blanpain uncovered the cells at the origin of BCC (Youssef et al, Nature Cell Biology, 2010). http://medicalxpress.com/news/2012-11-uncover-molecular-mechanisms-basal-cell.html Cancer Mon, 26 Nov 2012 09:40:01 EST news273144152 Taxpayers will be spending over $700m annually to treat Australia's most common skin cancers by the year 2015, with over-65s making up the bulk of patients, a new study has found. http://medicalxpress.com/news/2012-11-skin-cancer-bill-skyrocket-australian.html Cancer Mon, 19 Nov 2012 08:40:02 EST news272533556 (Medical Xpress)—Researchers at Moffitt Cancer Center, the University of South Florida and the International Agency for Research on Cancer in France have studied the patterns and timing of sunlight exposure and how each is related to two nonmelanoma skin cancers – basal cell carcinoma and squamous cell carcinoma. http://medicalxpress.com/news/2012-10-patterns-sunlight-exposure-contribute-skin.html Cancer Tue, 23 Oct 2012 11:39:58 EST news270210804 (Medical Xpress)—In a series of a half-dozen operations spanning 20 months, surgeons at Johns Hopkins have successfully reconstructed the entire ear and part of the skull of a 42-year-old woman from Bel Air, Md. http://medicalxpress.com/news/2012-09-surgeons-woman-tissue-rebuild-ear.html Surgery Thu, 27 Sep 2012 08:36:14 EST news267953758 (HealthDay)—Nonmelanoma skin cancers (NMSCs) commonly occur after pancreas transplantation (PT), particularly in those who have a history of skin cancer, according to a study published in the October issue of the Journal of the American Academy of Dermatology. http://medicalxpress.com/news/2012-09-skin-cancer-incidence-pancreas-transplantation.html Cancer Fri, 21 Sep 2012 14:20:01 EST news267452035 (HealthDay) -- Superficial X-ray therapy remains a viable treatment for primary basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in select patients, according to a study published online July 23 in the Journal of the American Academy of Dermatology. http://medicalxpress.com/news/2012-08-superficial-x-ray-viable-basal-squamous.html Cancer Mon, 06 Aug 2012 19:00:01 EST news263492832 In the powerful sunlight of July, newly published results from a large study of people at high risk for basal cell carcinoma support the emerging view of the nation's most common cancer as a chronic ailment that often repeatedly afflicts older people but for which the seeds may be planted in youth. The research also found a new association with eczema. http://medicalxpress.com/news/2012-07-basal-cell-carcinoma-chronic.html Cancer Wed, 25 Jul 2012 16:54:05 EST news262454038 Increasing the number of cups of caffeinated coffee you drink could lower your risk of developing the most common form of skin cancer, basal cell carcinoma, according to a study published in Cancer Research, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2012-07-coffee-consumption-inversely-common-skin.html Cancer Mon, 02 Jul 2012 04:20:01 EST news260420802 Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and the German Cancer Research Center in Heidelberg have found that having antibodies for cutaneous types of human papillomavirus (HPV), coupled with sun exposure (ultraviolet radiation) or poor tanning ability, can act "synergistically" in the development of non-melanoma skin cancers such as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). http://medicalxpress.com/news/2012-06-sun-exposure-cutaneous-hpv-infection.html Cancer Mon, 25 Jun 2012 12:10:04 EST news259844681 Combining a new targeted therapy with standard chemotherapy may help defeat pancreatic cancer, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, held here June 18-21. http://medicalxpress.com/news/2012-06-inhibiting-hedgehog-pathway-pancreatic-cancer.html Cancer Tue, 19 Jun 2012 11:09:35 EST news259322966 A customized patch treatment for basal cell carcinoma completely destroys facial tumors without surgery or major radiation therapy in 80 percent of patients studied, say researchers at the Society of Nuclear Medicine's 2012 Annual Meeting. http://medicalxpress.com/news/2012-06-skin-patch-treatment-common-cancer.html Cancer Mon, 11 Jun 2012 13:22:22 EST news258639737 A new drug has been shown to be effective in treating and preventing the most common cancer in the United States: basal cell carcinoma skin cancer, according to a new study in the New England Journal of Medicine to be published June 7. http://medicalxpress.com/news/2012-06-drug-effective-skin-cancer.html Cancer Wed, 06 Jun 2012 17:00:42 EST news258217778 Skin cancer patients whose childhood included periods of neglect or maltreatment are at a much greater risk for their cancers to return when they face a major stressful event, based on a new study. http://medicalxpress.com/news/2012-06-early-childhood-neglect-adult-skin.html Psychology & Psychiatry Mon, 04 Jun 2012 16:01:39 EST news258037117 (HealthDay) -- For patients with superficial basal cell carcinoma (sBCC), treatment with imiquimod or photodynamic therapy (PDT) results in similar long-term tumor-free survival, according to a review published online May 21 in the British Journal of Dermatology. http://medicalxpress.com/news/2012-05-common-therapies-basal-cell-carcinoma.html Cancer Fri, 25 May 2012 13:20:01 EST news257166747 (HealthDay) -- Basal cell carcinoma (BCC) on the ear is significantly more likely to be aggressive, and occurs more frequently in men, according to a study published in the May issue of the Journal of the American Academy of Dermatology. http://medicalxpress.com/news/2012-04-basal-cell-carcinoma-ear-significantly.html Diseases, Conditions, Syndromes Wed, 18 Apr 2012 14:30:01 EST news253976610 (HealthDay) -- The long-term risk of squamous cell carcinoma (SCC) is significantly increased for patients with severe psoriasis who receive more than 350 psoralen and ultraviolet A (PUVA) treatments compared with those who receive fewer than 50 treatments, according to research published in the April issue of the Journal of the American Academy of Dermatology. http://medicalxpress.com/news/2012-03-psoriasis-treatment-skin-cancer.html Cancer Thu, 29 Mar 2012 13:12:00 EST news252245484 These days, most of us don't head to the doctor until we are already ill. What if you could see disease approaching just as it starts to head your way? A study in a special March 16th issue of Cell focused on human biology shows that this futuristic notion is already in reach. Scientists have combined a complete personal genome sequence with analyses of disease risks and an array of dynamic molecular measures, capturing important changes in the way the human body works. The study is the first to apply "integrative Personal Omics Profiling" (iPOP for short) to observe healthy and diseased states, the researchers say. http://medicalxpress.com/news/2012-03-disease-unprecedented.html Genetics Thu, 15 Mar 2012 12:02:29 EST news251031731 (HealthDay) -- Use of tanning beds, especially in high school and college, is associated with an increased risk of skin cancer, according to a study published online Feb. 27 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-02-dose-response-link-tanning-bed-skin.html Cancer Tue, 28 Feb 2012 16:30:01 EST news249657916 A new skin cancer drug tested for the first time in the world five years ago at the Virginia G. Piper Cancer Center at Scottsdale Healthcare just received expedited approval by the U.S. Food and Drug Administration, a remarkable accomplishment in new drug development. http://medicalxpress.com/news/2012-02-fda-skin-cancer-drug.html Cancer Wed, 01 Feb 2012 13:13:19 EST news247324388 (AP) -- Federal regulators on Monday approved a pill that treats the most common type of skin cancer, basal cell carcinoma. http://medicalxpress.com/news/2012-01-fda-roche-skin-cancer-drug.html Medications Mon, 30 Jan 2012 12:10:01 EST news247146653 (Medical Xpress) -- The genes which contribute to the most frequently occurring life threatening form of skin cancer have been identified for the first time by a research collaboration between the University of Dundee and scientists at Harvard and University of California, San Francisco. http://medicalxpress.com/news/2011-11-skin-cancer-genes.html Cancer Thu, 10 Nov 2011 09:30:01 EST news240136164 Researchers confirmed an association between tanning bed use and an increased risk for three common skin cancers — basal cell carcinoma, squamous cell carcinoma and melanoma, according to results presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011. http://medicalxpress.com/news/2011-10-tanning-bed-deadly-skin-cancers.html Cancer Mon, 24 Oct 2011 17:59:20 EST news238697918 Caffeine could be related to an inverse association between basal cell carcinoma risk and consumption of coffee, a study found. http://medicalxpress.com/news/2011-10-coffee-consumption-decreased-basal-cell.html Cancer Mon, 24 Oct 2011 17:55:48 EST news238697731 Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome associated with risk of developing basal cell carcinoma of the skin (BCC), as well as prostate cancer and glioma, the most serious form of brain cancer. The study was done in collaboration with Illumina, Inc., and is published today in the online edition of Nature Genetics. http://medicalxpress.com/news/2011-09-genetic-factor-skin-prostate-brain.html Genetics Sun, 25 Sep 2011 17:15:41 EST news236187587 As an individual's level of vitamin D increases, the risk of nonmelanoma skin cancer (NMSC) seems to increase as well, although factors such as ultraviolet (UV) radiation exposure may complicate the relationship, according to a report published Online First by Archives of Dermatology. http://medicalxpress.com/news/2011-08-vitamin-d-skin-cancer-relationship.html Health Mon, 15 Aug 2011 17:37:47 EST news232648650 (PhysOrg.com) -- People with a genetic condition called basal cell nevus syndrome develop hundreds or even thousands of skin cancers, or basal cell carcinomas, each year. Now Jean Tang, MD, PhD, assistant professor of dermatology, is reporting that a drug produced by Genentech called GDC-0449 significantly slowed or stopped the development of tumors in each of 24 patients who received the drug, and caused existing tumors to shrink in size. http://medicalxpress.com/news/2011-04-basal-cell-carcinoma.html Cancer Mon, 11 Apr 2011 09:19:19 EST news221732335